• 1. Fate of single walled carbon nanotubes in wetland ecosystems?
  Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583
• 2. Excellent mechanical performance and enhanced dielectric properties of OBC/SiO2 elastomeric nanocomposites: effect of dispersion of the SiO2 nanoparticles?
  Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
• 3. Fc microparticles can modulate the physical extent and magnitude of complement activity?
  David White,Sean R. Stowell Biomater. Sci., 2017,5, 463-474
• 4. Enabling shape memory and healable effects in a conjugated polymer by incorporating siloxane via dynamic imine bond?
  Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
• 5. Empowering microfluidics by micro-3D printing and solution-based mineral coating?
  Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849

• Solvents and Organic Chemicals Organic Compounds Organosulfur compounds Thioureas Thioureas
• Solvents and Organic Chemicals Organic Compounds Organosulfur compounds Thioureas

Comprehensive Overview of 1,3-Di-tert-butylthiourea (CAS No. 4041-95-6): Properties, Applications, and Industry Insights

1,3-Di-tert-butylthiourea (CAS 4041-95-6), a specialized thiourea derivative, has garnered significant attention in industrial and research sectors due to its unique chemical properties. This compound, characterized by its tert-butyl groups and thiocarbonyl functionality, serves as a versatile intermediate in organic synthesis and material science. With growing interest in sustainable chemistry and high-performance additives, this molecule aligns with modern demands for efficiency and environmental compatibility.

The molecular structure of 1,3-Di-tert-butylthiourea features steric hindrance from its bulky tert-butyl substituents, which influences its reactivity in catalysis and polymer stabilization. Recent studies highlight its role in rubber vulcanization accelerators, where it improves crosslinking efficiency while reducing scorch time—a critical factor for manufacturers optimizing production workflows. This aligns with the industry's focus on energy-efficient processes, a frequently searched topic in material science forums.

In pharmaceutical research, the thiourea moiety of this compound demonstrates potential as a hydrogen bond donor in drug design, particularly for targeting enzyme inhibition. While not an API itself, its structural features contribute to the development of bioactive molecules, a subject trending in medicinal chemistry discussions. Researchers often query about nitrogen-sulfur heterocycles and their applications, making this compound relevant to current explorations.

From an analytical perspective, CAS 4041-95-6 exhibits distinct spectroscopic signatures—its IR spectrum shows characteristic thiourea C=S stretching at 1100-1250 cm?1, while NMR reveals deshielded protons due to steric effects. These properties make it identifiable in quality control protocols, addressing another common search theme among analytical chemists seeking compound characterization techniques.

The compound's thermal stability (decomposition >200°C) suits applications in high-temperature polymers, coinciding with market interest in heat-resistant materials for automotive and aerospace sectors. Its low water solubility but solubility in organic solvents like dichloromethane and THF facilitates its use in non-aqueous systems, a practical consideration for formulators.

Environmental and handling aspects of 1,3-Di-tert-butylthiourea follow standard laboratory safety protocols. While not classified as hazardous under major regulatory frameworks, proper PPE usage (gloves, goggles) is recommended—addressing frequently searched chemical safety guidelines. Storage in amber glass under inert atmosphere preserves stability, a detail often queried by procurement specialists.

Market trends indicate rising demand for specialty thioureas in Asia-Pacific regions, driven by polymer industries and R&D investments. The compound's cost-performance ratio compared to analogous N,N'-dialkylthioureas makes it economically attractive, a point analyzed in recent chemical economics reports. This connects with commercial searches for alternative chemical intermediates.

Future research directions may explore its coordination chemistry with transition metals for catalytic applications, or its potential in supramolecular assemblies—both trending topics in academic literature. Patent analyses reveal incremental innovations utilizing this compound in specialty coatings, suggesting untapped potential in material sciences.

For quality assurance, suppliers typically provide HPLC purity certificates (>98%) and residual solvent analysis, addressing compliance needs in GMP environments. These specifications respond to purchaser concerns about batch-to-batch consistency, a critical factor in industrial applications.

• 13120-05-3(Thiourea, N-butyl-N'-(1,1-dimethylethyl)-)
• 731742-74-8(Thiourea,N-(1,1-dimethylethyl)-N-methyl-)
• 62351-11-5(Thiourea, N-(1-methylethyl)-N'-propyl-)
• 32900-08-6(Thiourea,N-cyclopropyl-N'-ethyl-)
• 2986-17-6(1,3-bis(propan-2-yl)thiourea)
• 7204-48-0(1-tert-Butyl-2-thiourea)
• 13057-37-9(Thiourea,N,N''-1,2-ethanediylbis[N'-(1,1-dimethylethyl)- (9CI))
• 1719-76-2(1-Isopropylthiourea)
• 52599-24-3(3-tert-Butyl-1-(propan-2-yl)thiourea)
• 59814-70-9(1,3-dicyclopropylthiourea)