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• 2. An amphoteric reactivity of a mixed-valent bis(μ-oxo)dimanganese(iii,iv) complex acting as an electrophile and a nucleophile?
  Muniyandi Sankaralingam,So Hyun Jeon,Yong-Min Lee,Mi Sook Seo,Wonwoo Nam Dalton Trans., 2016,45, 376-383
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• 4. An automatic determination of thoria in thoria-urania mixtures
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• 5. An intermolecular C–H oxidizing strategy to access highly fused carbazole skeletons from simple naphthylamines?
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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Isoindoles and derivatives Isoindolones
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Isoindoles and derivatives Isoindolines Isoindolones

Comprehensive Overview of 4-Methylphthalimide (CAS No. 40314-06-5): Properties, Applications, and Industry Insights

4-Methylphthalimide (CAS No. 40314-06-5) is an organic compound belonging to the phthalimide family, characterized by a methyl group substitution at the 4-position of the phthalimide ring. This structural modification imparts unique chemical and physical properties, making it a valuable intermediate in pharmaceuticals, agrochemicals, and advanced material synthesis. With the growing demand for heterocyclic compounds in drug discovery and high-performance polymers, 4-Methylphthalimide has garnered significant attention from researchers and industrial applications alike.

The compound’s molecular formula, C₉H₇NO₂, and its crystalline solid form under standard conditions make it a stable candidate for various synthetic processes. Its thermal stability and solubility in organic solvents like ethanol and dimethylformamide (DMF) further enhance its utility in laboratory and industrial settings. Recent studies highlight its role as a precursor for fluorescent dyes and photoactive materials, aligning with the surge in demand for organic electronic components and sustainable chemistry solutions.

In the pharmaceutical sector, 4-Methylphthalimide derivatives are explored for their potential bioactive properties, including antimicrobial and anti-inflammatory effects. This aligns with the global trend toward targeted drug delivery systems and small-molecule therapeutics. Additionally, its incorporation into polyimide resins contributes to the development of heat-resistant coatings and adhesives, addressing needs in aerospace and electronics industries.

From an environmental perspective, the compound’s low volatility and minimal ecological toxicity (green chemistry metrics) position it favorably compared to traditional aromatic intermediates. Researchers are also investigating its degradation pathways to ensure compliance with REACH regulations and industrial waste management standards—a critical consideration for manufacturers prioritizing ESG (Environmental, Social, and Governance) compliance.

The synthesis of 4-Methylphthalimide typically involves the condensation of 4-methylphthalic anhydride with urea or ammonia, followed by purification. Innovations in catalytic processes and solvent-free reactions have improved yield efficiency, reducing energy consumption—a response to the industry’s push for carbon footprint reduction. Analytical techniques like HPLC and mass spectrometry ensure high purity (>98%), meeting stringent requirements for fine chemical applications.

Market trends indicate rising demand for 4-Methylphthalimide in Asia-Pacific regions, driven by expansions in pharmaceutical manufacturing and electronic material production. Frequently searched queries such as "4-Methylphthalimide solubility", "CAS 40314-06-5 suppliers", and "phthalimide derivatives in drug design" reflect diverse user interests, from academic research to industrial procurement. Suppliers increasingly emphasize batch-to-batch consistency and regulatory documentation to cater to these needs.

Future research directions may explore 4-Methylphthalimide’s potential in metal-organic frameworks (MOFs) for gas storage or its role in photocatalysis. As industries prioritize circular economy models, recycling protocols for phthalimide-based byproducts could further enhance its sustainability profile. Collaborative efforts between academia and enterprises will likely accelerate innovations, solidifying 4-Methylphthalimide’s position as a versatile building block in modern chemistry.

• 33081-78-6(Sodium phthalimide)
• 66393-65-5(2H-Isoindol-2-yl, 1,3-dihydro-1,3-dioxo-)
• 7251-82-3(4-methylisoindoline-1,3-dione)
• 1074-82-4(potassium 1,3-dioxo-2,3-dihydro-1H-isoindol-2-ide)
• 2550-73-4(Pyromellitic diimide)
• 53510-88-6(Phthalimide-15N Potassium Salt)
• 480-91-1(2,3-dihydro-1H-isoindol-1-one)
• 60161-31-1(Phthalimide-d4)
• 20197-78-8(5,6-dimethyl-1H-Isoindole-1,3(2H)-dione)
• 89292-13-7(1H-Isoindole-1,3(2H)-dione, 5-methyl-, potassium salt)