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  Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198
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  Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
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• Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Stilbenes Stilbenes
• Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Stilbenes
• Solvents and Organic Chemicals Organic Compounds Acids/Esters
• Solvents and Organic Chemicals Organic Compounds Hydrocarbons

Comprehensive Guide to 4-(E)-2-Phenylethenylbenzaldehyde (CAS No. 40200-69-9): Properties, Applications, and Market Insights

4-(E)-2-Phenylethenylbenzaldehyde (CAS No. 40200-69-9) is a versatile organic compound widely used in the synthesis of fine chemicals, pharmaceuticals, and advanced materials. This aromatic aldehyde, featuring a trans-stilbene backbone, has garnered significant attention due to its unique photophysical properties and potential applications in organic electronics and fluorescence probes. Researchers and industries are increasingly exploring its derivatives for OLED materials and bioimaging agents, aligning with the growing demand for sustainable technologies.

The compound’s molecular structure consists of a benzaldehyde moiety linked to a styrene group via an ethenyl bridge, which contributes to its conjugated π-system. This conjugation enables 4-(E)-2-Phenylethenylbenzaldehyde to exhibit strong UV-Vis absorption and emissive behavior, making it valuable for optoelectronic applications. Recent studies highlight its role in developing non-linear optical materials, a hot topic in photonics research.

In the pharmaceutical sector, 4-(E)-2-Phenylethenylbenzaldehyde serves as a key intermediate for synthesizing antioxidant and anti-inflammatory agents. Its derivatives are investigated for potential neuroprotective effects, coinciding with the rising interest in neurodegenerative disease therapeutics. Additionally, its Schiff base derivatives are studied for metal ion sensing, addressing environmental concerns about heavy metal detection.

The market for 4-(E)-2-Phenylethenylbenzaldehyde is expanding, driven by demand from material science and life sciences. Suppliers emphasize high-purity grades to meet research and industrial standards, while green synthesis methods gain traction to align with sustainability goals. Analytical techniques like HPLC and NMR ensure quality control, critical for applications in precision medicine and nanotechnology.

For researchers seeking CAS 40200-69-9, understanding its storage conditions (e.g., light-sensitive, under inert atmosphere) and handling protocols is essential. The compound’s solubility in organic solvents like DMSO and ethanol facilitates its use in diverse reactions. FAQs often revolve around its stability, derivatization routes, and scalability—topics frequently searched in chemical databases and AI-driven literature tools.

In summary, 4-(E)-2-Phenylethenylbenzaldehyde bridges gaps between academic research and industrial innovation. Its multifunctionality positions it as a cornerstone in developing next-generation materials and therapeutic candidates, resonating with trends like green chemistry and personalized medicine.

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