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• 2. An antioxidative galactomannan extracted from Chinese Sesbania cannabina enhances immune activation of macrophage cells?
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• 3. An arsenic trioxide nanoparticle prodrug (ATONP) potentiates a therapeutic effect on an aggressive hepatocellular carcinoma model via enhancement of intratumoral arsenic accumulation and disturbance of the tumor microenvironment?
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• 4. An asymmetric supercapacitor based on controllable WO3 nanorod bundle and alfalfa-derived porous carbon?
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Comprehensive Overview of 2-(morpholin-3-yl)ethan-1-ol (CAS No. 399580-64-4): Properties, Applications, and Industry Insights

2-(morpholin-3-yl)ethan-1-ol (CAS No. 399580-64-4) is a versatile organic compound gaining traction in pharmaceutical and chemical research. Its unique molecular structure, featuring a morpholine ring and a hydroxyl-terminated ethyl chain, makes it valuable for synthesizing bioactive molecules. Researchers frequently search for "morpholine derivatives in drug discovery" or "CAS 399580-64-4 solubility," reflecting its relevance in modern R&D. This article explores its properties, applications, and answers trending queries like "how to stabilize 2-(morpholin-3-yl)ethanol"—a common concern in lab settings.

The compound’s physicochemical properties include a molecular weight of 131.17 g/mol and a balanced lipophilicity-hydrophilicity profile, ideal for medicinal chemistry. Its boiling point (~250°C) and water solubility (moderate) are frequently queried, as they impact formulation design. Recent studies highlight its role as a building block for kinase inhibitors, aligning with the surge in "targeted cancer therapy" searches. Unlike traditional intermediates, 2-(morpholin-3-yl)ethan-1-ol offers low toxicity, a critical factor given the growing demand for "green chemistry alternatives."

In pharmaceutical applications, this compound serves as a precursor for neuroactive agents and anti-inflammatory drugs. Its morpholine moiety enhances blood-brain barrier permeability, a hot topic in "CNS drug development" forums. Industry reports correlate its use with patents for G-protein-coupled receptor (GPCR) modulators, addressing the rising interest in "orphan receptor targets." Analytical methods like HPLC purification and NMR characterization are often discussed alongside CAS 399580-64-4, as purity (>98%) is crucial for reproducibility.

Beyond pharma, 2-(morpholin-3-yl)ethan-1-ol finds niche roles in agrochemicals and material science. Its derivatization into UV stabilizers responds to the "polymer durability" trend, while queries like "morpholine-based corrosion inhibitors" underscore industrial potential. Storage recommendations (e.g., argon atmosphere to prevent oxidation) are frequently searched, reflecting practical handling challenges. The compound’s stereochemistry also attracts attention, with studies exploring its chiral resolution for asymmetric synthesis.

Emerging applications include bioconjugation for antibody-drug conjugates (ADCs), a field booming due to "next-gen biotherapeutics" demand. Its PEG-like properties enable solubility enhancement, a recurring theme in "formulation optimization" discussions. Regulatory databases list it as non-hazardous under standard conditions, though users often seek "CAS 399580-64-4 safety data"—a testament to evolving lab safety awareness. Future prospects may link to "AI-driven molecular design," where morpholine scaffolds are algorithmically prioritized.

In summary, 2-(morpholin-3-yl)ethan-1-ol bridges academic inquiry and industrial innovation. Its alignment with search trends—from "scalable synthesis" to "structure-activity relationships"—positions it as a compound of enduring interest. As researchers prioritize "fragment-based drug design" and "sustainable intermediates," CAS 399580-64-4 will likely remain a keystone in synthetic chemistry.

• 1432793-78-6((S)-2-(Morpholin-3-yl)ethanol hydrochloride)
• 38711-87-4(3-Ethyl-5-methylmorpholine)
• 1628617-14-0(2-(Morpholin-3-yl)ethanol hydrochloride)
• 1386999-20-7(3-(2-methoxyethyl)morpholine)
• 55265-24-2(3-ethylmorpholine)
• 74572-05-7((3R)-3-ethylmorpholine)
• 761460-05-3((S)-2-(Morpholin-3-yl)ethanol)
• 74811-65-7(Croscarmellose sodium)
• 748117-01-3((3S)-3-ethylmorpholine)
• 917572-32-8((R)-2-(Morpholin-3-yl)ethanol)