Cas no 39743-20-9 (1-(3-Chloropropyl)pyrrolidine)

1-(3-Chloropropyl)pyrrolidine is a versatile organic compound featuring a pyrrolidine ring linked to a chloropropyl group. This structure makes it a valuable intermediate in organic synthesis, particularly for the preparation of pharmaceuticals, agrochemicals, and specialty chemicals. The reactive chloropropyl moiety allows for further functionalization, enabling the introduction of the pyrrolidine scaffold into more complex molecules. Its stability and compatibility with a range of reaction conditions enhance its utility in multi-step synthetic routes. The compound is commonly employed in nucleophilic substitution reactions, cyclizations, and as a building block for heterocyclic systems. Proper handling is advised due to its potential reactivity.
1-(3-Chloropropyl)pyrrolidine structure
1-(3-Chloropropyl)pyrrolidine structure
Product Name:1-(3-Chloropropyl)pyrrolidine
CAS No:39743-20-9
MF:C7H14ClN
MW:147.645761013031
MDL:MFCD09864848
CID:55086
PubChem ID:11321028
Update Time:2025-10-29

1-(3-Chloropropyl)pyrrolidine Chemical and Physical Properties

Names and Identifiers

    • 1-(3-Chloropropyl)pyrrolidine
    • 1-(3-Chloropropyl)-pyrrolidine
    • (3-Chloropropyl)pyrrolidine, HCl
    • 3-pyrrolidino-n-propyl chloride
    • Pyrrolidine, 1-(3-chloropropyl)-
    • (3-chloropropyl)pyrrolidine
    • (3-pyrrolidinopropyl)chloride
    • 3-pyrrolidino-propyl chloride
    • 1-chloro-3-pyrrolidinopropane
    • N-(3-chloropropyl)pyrrolidine
    • 1-(3-chloropropanyl)pyrrolidine
    • 1-(3-chloro-propyl)pyrrolidine
    • 1-(3-Chloro-propyl)-pyrrolidine
    • SPRTXTPFQKHSBG-UHFFFAOYSA-N
    • Pyrrolidine,1-(3-chloropropyl)-
    • 3-(pyrrolidin-1-yl)propyl chlo
    • BB 0254512
    • AC-17193
    • DS-12350
    • SCHEMBL73078
    • AKOS000265259
    • 39743-20-9
    • EN300-55017
    • A23158
    • p-cyanophenyltrans-4-propylcyclohexanecarboxylate
    • D70826
    • FT-0649341
    • CS-0155277
    • DTXSID70462191
    • 3-(pyrrolidin-1-yl)propyl chloride
    • CHEMBL4597564
    • N-chloropropyl pyrrolidine
    • ALBB-007086
    • DB-012758
    • STK504284
    • MDL: MFCD09864848
    • Inchi: 1S/C7H14ClN/c8-4-3-7-9-5-1-2-6-9/h1-7H2
    • InChI Key: SPRTXTPFQKHSBG-UHFFFAOYSA-N
    • SMILES: ClCCCN1CCCC1

Computed Properties

  • Exact Mass: 147.08100
  • Monoisotopic Mass: 147.0814771g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 9
  • Rotatable Bond Count: 3
  • Complexity: 69.3
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 3.2
  • XLogP3: 1.7

Experimental Properties

  • Color/Form: No data available
  • Density: 1.016
  • Melting Point: No data available
  • Boiling Point: 194.5℃ at 760 mmHg
  • Flash Point: 71.4°C
  • Refractive Index: 1.474
  • PSA: 3.24000
  • LogP: 1.64900

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1-(3-Chloropropyl)pyrrolidine Production Method

1-(3-Chloropropyl)pyrrolidine Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:39743-20-9)1-(3-Chloropropyl)pyrrolidine
Order Number:A23158
Stock Status:in Stock
Quantity:100g/25g
Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 16:02
Price ($):652.0/191.0

Additional information on 1-(3-Chloropropyl)pyrrolidine

Comprehensive Guide to 1-(3-Chloropropyl)pyrrolidine (CAS No. 39743-20-9): Properties, Applications, and Industry Insights

1-(3-Chloropropyl)pyrrolidine (CAS 39743-20-9) is a versatile organic intermediate widely utilized in pharmaceutical synthesis, agrochemical production, and specialty chemical manufacturing. This compound, characterized by its pyrrolidine ring and reactive 3-chloropropyl side chain, has garnered significant attention due to its role in constructing complex molecular architectures. As researchers and industries increasingly focus on sustainable chemistry and high-efficiency synthesis, understanding this compound's properties becomes essential.

The molecular structure of 1-(3-Chloropropyl)pyrrolidine combines a heterocyclic amine with an alkyl chloride moiety, making it a valuable building block for N-alkylation reactions. Recent trends in green chemistry have driven innovations in its synthesis, with studies exploring catalyst-free methods and solvent optimization to reduce environmental impact. These advancements align with global demands for eco-friendly chemical processes, a topic frequently searched in academic and industrial forums.

In pharmaceutical applications, CAS 39743-20-9 serves as a precursor for bioactive molecules, particularly those targeting central nervous system disorders. Its pyrrolidine scaffold is a privileged structure in drug design, often associated with improved blood-brain barrier permeability. This relevance connects to trending searches about neuropharmaceutical development and drug delivery optimization, making it a compound of interest for researchers worldwide.

The compound's stability and reactivity profile have also made it valuable in material science, particularly for modifying polymer surfaces and creating functionalized nanomaterials. With the growing emphasis on smart materials in electronics and coatings, 1-(3-Chloropropyl)pyrrolidine offers unique opportunities for surface engineering – a subject frequently queried in material science databases and patent literature.

Analytical characterization of 39743-20-9 typically involves GC-MS, NMR spectroscopy, and HPLC purity testing, reflecting the compound's importance in quality-controlled synthesis. These techniques align with current industry priorities for analytical method validation, a hot topic in regulatory compliance discussions. Proper handling requires standard laboratory safety protocols, though it doesn't fall under restricted categories.

Market analyses indicate rising demand for 1-(3-Chloropropyl)pyrrolidine across Asia-Pacific regions, driven by expanding pharmaceutical R&D and contract manufacturing activities. This correlates with increased search volumes for specialty chemical suppliers and custom synthesis services. The compound's cost-effectiveness compared to similar intermediates further enhances its commercial appeal.

Future research directions may explore its potential in catalysis and asymmetric synthesis, areas gaining traction in academic publications. The compound's bifunctional nature makes it suitable for developing chiral auxiliaries – a subject frequently appearing in organic chemistry search queries. Such applications position CAS 39743-20-9 as a compound with untapped potential in advanced synthetic methodologies.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:39743-20-9)1-(3-Chloropropyl)pyrrolidine
A23158
Purity:99%/99%
Quantity:100g/25g
Price ($):652.0/191.0
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