• 1. Evidence of pre-micellar aggregates in aqueous solution of amphiphilic PDMS–PEO block copolymer?
  Domenico Lombardo,Gianmarco Munaò,Pietro Calandra,Luigi Pasqua,Maria Teresa Caccamo Phys. Chem. Chem. Phys., 2019,21, 11983-11991
• 2. Excimer and exciplex formation in a pair of bright phosphorescent isomers constructed from Cu3(pyrazolate)3 and Cu3I3 coordination luminophores?
  Shun-Ze Zhan,Mian Li,Xiao-Ping Zhou,Dan Li,Seik Weng Ng RSC Adv., 2011,1, 1457-1459
• 3. Examination of ammonia–poly(pyrrole) interactions by piezoelectric and conductivity measurements
  Analyst, 1991,116, 1125-1130
• 4. Fast-pulsing NMR techniques for the detection of weak interactions: successful natural abundance probe of hydrogen bonds in peptides?
  Amandine Altmayer-Henzien,Valérie Declerck,David J. Aitken,Ewen Lescop,Denis Merlet,Jonathan Farjon Org. Biomol. Chem., 2013,11, 7611-7615
• 5. Excited state dynamics of symmetric and asymmetric Cr3(dpa)4Cl2 measured using femtosecond transient absorption spectroscopy?
  Chao-Han Cheng,Wen-Zhen Wang,Shie-Ming Peng,I-Chia Chen Phys. Chem. Chem. Phys., 2017,19, 25471-25477

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Keto acids and derivatives Gamma-keto acids and derivatives

Comprehensive Guide to 4-(3-methyl-2-thienyl)-4-oxo-butanoic acid (CAS No. 39712-64-6): Properties, Applications, and Market Insights

4-(3-methyl-2-thienyl)-4-oxo-butanoic acid (CAS No. 39712-64-6) is a specialized organic compound that has garnered significant attention in pharmaceutical and chemical research. This compound, characterized by its unique thiophene ring structure and carboxylic acid functionality, serves as a versatile intermediate in synthetic chemistry. Its molecular formula, C9H10O3S, reflects a balance of reactivity and stability, making it valuable for diverse applications.

The growing interest in heterocyclic compounds like 4-(3-methyl-2-thienyl)-4-oxo-butanoic acid is driven by their role in drug discovery. Researchers frequently search for "thiophene derivatives in medicine" or "CAS 39712-64-6 applications," highlighting its relevance in developing anti-inflammatory agents and central nervous system (CNS) drugs. The compound’s keto-acid moiety enables facile derivatization, aligning with trends in structure-activity relationship (SAR) studies.

From a synthetic perspective, 4-(3-methyl-2-thienyl)-4-oxo-butanoic acid is synthesized via Friedel-Crafts acylation of 3-methylthiophene, followed by oxidation. Its melting point (～120–125°C) and solubility in polar solvents like ethanol or DMSO are critical for laboratory handling. These properties are often queried as "39712-64-6 solubility" or "thermal stability of thienyl keto acids," reflecting practical user concerns.

In industrial contexts, this compound is pivotal for producing high-value fine chemicals. Market reports indicate rising demand for thiophene-based intermediates, with applications spanning agrochemicals, material science, and flavor/fragrance synthesis. SEO-optimized queries such as "buy 4-(3-methyl-2-thienyl)-4-oxo-butanoic acid" or "suppliers of CAS 39712-64-6" underscore its commercial significance.

Environmental and regulatory aspects of 4-(3-methyl-2-thienyl)-4-oxo-butanoic acid are also trending topics. While not classified as hazardous, its handling requires standard laboratory safety protocols. Users often seek "CAS 39712-64-6 SDS" or "biodegradability of thiophene derivatives," emphasizing the need for sustainable chemistry practices.

Future research directions for 39712-64-6 include exploring its potential in catalysis and polymeric materials. Innovations in green chemistry may further enhance its synthesis efficiency, addressing queries like "eco-friendly production of keto acids." As the pharmaceutical industry expands, this compound’s role in precision medicine and bioconjugation is expected to grow.

In summary, 4-(3-methyl-2-thienyl)-4-oxo-butanoic acid exemplifies the intersection of synthetic utility and industrial relevance. Its adaptability to evolving scientific needs ensures sustained interest, mirrored in frequent searches for "thienyl keto acid derivatives" and "CAS 39712-64-6 price trends." This guide aims to equip researchers and industry professionals with actionable insights into this multifaceted compound.

• 20905-96-8(8H-Cyclohepta[b]thiophen-8-one,4,5,6,7-tetrahydro-)
• 1468-84-4(5,6-Dihydrobenzobthiophen-7(4H)-one)
• 71308-22-0(1-Dodecanone, 1-(3-methyl-2-thienyl)-)
• 1379312-51-2(Methyl 3-(3-methylthiophen-2-yl)-3-oxopropanoate)
• 70704-06-2(1-Pentanone, 1-(3-methyl-2-thienyl)-)
• 5650-52-2(4,5-dihydrocyclopenta[b]thiophen-6-one)
• 59303-03-6(1-Propanone,1-(3-methyl-2-thienyl)-)
• 59782-63-7(1-Decanone, 1-(4-methyl-5-tridecyl-2-thienyl)-)
• 60089-61-4(1-Eicosanone, 1-(4-methyl-5-tridecyl-2-thienyl)-)
• 67839-03-6(6H-CYCLOPENTA[B]THIOPHEN-6-ONE, 4,5-DIHYDRO-2-METHYL-)