Cas no 39262-22-1 ((1R)-(-)-10-Camphorsulfonyl Chloride)

(1R)-(-)-10-Camphorsulfonyl Chloride is a chiral sulfonylating agent widely used in asymmetric synthesis and pharmaceutical applications. Its rigid camphor-derived structure imparts high stereoselectivity, making it valuable for the preparation of enantiomerically pure compounds. The compound reacts efficiently with nucleophiles, enabling the introduction of the camphorsulfonyl (Camsyl) group, which serves as a versatile protecting or directing group in organic transformations. Its high reactivity and optical purity (>98%) ensure reliable performance in stereocontrolled reactions. Additionally, the (1R)-(-) enantiomer is particularly useful for resolving racemic mixtures and synthesizing chiral intermediates. The product is typically handled under anhydrous conditions due to its moisture sensitivity.

(1R)-(-)-10-Camphorsulfonyl Chloride structure

39262-22-1 structure

Product Name:(1R)-(-)-10-Camphorsulfonyl Chloride

CAS No:39262-22-1

MF:C₁₀H₁₅ClO₃S

MW:250.742301225662

MDL:MFCD00064155

CID:55003

PubChem ID:24858220

Update Time:2025-10-20

(1R)-(-)-10-Camphorsulfonyl Chloride Chemical and Physical Properties

Names and Identifiers

- ((1R,4S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride
- (1R)-(-)-10-CAMPHORSULFONYL CHLORIDE
- (1R)-(-)-CAMPHOR-10-SULFONIC ACID CHLORIDE
- (1R)-CAMPHOR-10-SULFONIC ACID CHLORIDE
- (1R)-(-)-CAMPHOR-10-SULFONYL CHLORIDE
- (1R)-(-)-CAMPHOR-10-SULPHONYL CHLORIDE
- (-)-CAMPHOR-10-SULFONYL CHLORIDE
- L(-)-10-CAMPHORSULFONYL CHLORIDE
- 6,(1R)-(-)-10-Camphorsulfonylchloride
- Bicyclo2.2.1heptane-1-methanesulfonyl chloride, 7,7-dimethyl-2-oxo-, (1R,4S)-
- (-)-Camphor-10-sulphonyl chloride
- (-)-Camphor-10-sulfonyl chloride, (1R)-Camphor-10-sulfonic acid chloride
- (7,7-Dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl)methanesulfonyl chloride
- (1R,4S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfochloride
- [1R,4R,(-)]-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid chloride
- (-)-10-Camphorsulfonyl Chloride
- ((1R,4S)-7,7-Dimethyl-2-oxobicyclo-[2.2.1]heptan-1-yl)methanesulfonyl chloride
- L-10-Camphorsulfonyl chloride
- (?)-Camphor-10-sulfonyl chloride,(1R)-Camphor-10-sulfonic acid chloride
- [(1S,4R)-7,7-dimethyl-3-oxo-4-bicyclo[2.2.1]heptanyl]methanesulfonyl chloride
- L-(-)-10-Camphorsulfonyl chloride
- 10-Camphorsulfonyl chloride
- (7,7-Dimethyl-2-Oxo-Bicyclo[2.2.1]Hept-1-Yl)-Methanesulfonyl Chloride
- C10H15ClO3S
- [(1R,4S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl]methanesulfonyl chloride
- PubChem8092
- KSC914S0B
- D-(?)-Camphorsulfonyl chl
- AS-19113
- D-Camphor-10-sulfonyl chloride
- [(1R,4S)-7,7-dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl]methanesulfonyl chloride
- DTXSID10431225
- 10-Camphorsulfonyl chloride, 98%
- SCHEMBL12706679
- CS-W014100
- (1r,4s)-camphor-10-sulfonic acid chloride
- FD1220
- (1R)-(-)-10-Camphorsulfonyl chloride, for chiral derivatization, 97.0-103.0% (AT)
- MFCD00064155
- F0001-2351
- 39262-22-1
- L-10-Camphorsulfonylchloride
- A824492
- (1R)-(-)-10-Camphorsulfonyl chloride, 97%
- AKOS005146490
- BGABKEVTHIJBIW-XVKPBYJWSA-N
- (1R)-(-)-10-Camphorsulfonyl Chloride
- MDL： MFCD00064155
- Inchi： 1S/C10H15ClO3S/c1-9(2)7-3-4-10(9,8(12)5-7)6-15(11,13)14/h7H,3-6H2,1-2H3/t7-,10-/m0/s1
- InChI Key： BGABKEVTHIJBIW-XVKPBYJWSA-N
- SMILES： ClS(C[C@]12C(C[C@H](CC1)C2(C)C)=O)(=O)=O
- BRN： 3205975

Computed Properties

Exact Mass: 250.04300
Monoisotopic Mass: 250.043
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Heavy Atom Count: 15
Rotatable Bond Count: 2
Complexity: 407
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 2
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Surface Charge: 0
Tautomer Count: 2
XLogP3: 1.8
Topological Polar Surface Area: 59.6

Experimental Properties

Color/Form: solid
Density: 1.3310
Melting Point: 66.0 to 68.0 deg-C
Boiling Point: 349.408 °C at 760 mmHg
Flash Point: 165.116 °C
Refractive Index: 1.528
Water Partition Coefficient: decomposition
PSA: 59.59000
LogP: 3.03120
Sensitiveness: Moisture Sensitive
Specific Rotation: -33 o (c=3, chloroform)
Optical Activity: [α]18/D ?33°, c =?3 in chloroform
Solubility: React with water

(1R)-(-)-10-Camphorsulfonyl Chloride Security Information

Symbol:
Prompt：dangerous
Signal Word：Danger
Hazard Statement： H314
Warning Statement： P280,P305+P351+P338,P310
Hazardous Material transportation number：UN 3261
WGK Germany：3
Hazard Category Code： 34
Safety Instruction： S26-S36/37/39-S45
FLUKA BRAND F CODES：10-21
Hazardous Material Identification：
HazardClass：8
PackingGroup：III
Packing Group：II
Hazard Level：8
Risk Phrases：R34
Packing Group：II
Safety Term：8
Storage Condition：2-8°C

(1R)-(-)-10-Camphorsulfonyl Chloride Customs Data

HS CODE：29147090
Customs Data：

China Customs Code:
29147090

(1R)-(-)-10-Camphorsulfonyl Chloride Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.	301949-5G	(1R)-(-)-10-Camphorsulfonyl Chloride	39262-22-1	97%	5G	￥670.06	2022-02-24
Fluorochem	212015-1g	1R,4S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride	39262-22-1	95%	1g	￡10.00	2022-03-01
Fluorochem	212015-5g	1R,4S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride	39262-22-1	95%	5g	￡17.00	2022-03-01
Fluorochem	212015-25g	1R,4S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride	39262-22-1	95%	25g	￡60.00	2022-03-01
Fluorochem	212015-100g	1R,4S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride	39262-22-1	95%	100g	￡148.00	2022-03-01
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.	R028706-1g	(1R)-(-)-10-Camphorsulfonyl Chloride	39262-22-1	97%	1g	￥27	2023-09-09
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.	R028706-25g	(1R)-(-)-10-Camphorsulfonyl Chloride	39262-22-1	97%	25g	￥358	2023-09-09
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.	R028706-5g	(1R)-(-)-10-Camphorsulfonyl Chloride	39262-22-1	97%	5g	￥89	2023-09-09
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.	R028706-100g	(1R)-(-)-10-Camphorsulfonyl Chloride	39262-22-1	97%	100g	￥1201	2023-09-09
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.	R84330-25g	((1R,4S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride	39262-22-1		25g	￥808.0	2021-09-08

(1R)-(-)-10-Camphorsulfonyl Chloride Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd

Gold Member

Audited Supplier

(CAS:39262-22-1)(-)-10-樟腦磺酰氯

Order Number:LE1754579

Stock Status:in Stock

Quantity:25KG,200KG,1000KG

Purity:99%

Pricing Information Last Updated:Friday, 20 June 2025 12:36

Price ($):discuss personally

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(1R)-(-)-10-Camphorsulfonyl Chloride Related Literature

1. Asymmetric induction in the base induced rearrangement of N-(diphenylphosphinoyl)-O-(camphor-10-sulfonyl)hydroxylamine

Martin J. P. Harger,Ramesh Sreedharan-Menon J. Chem. Soc. Chem. Commun. 1994 1619
2. α-Chloronitroso compounds derived from carbohydrate ketones: cycloadditions with cyclic dienes, a synthesis of (–)-physoperuvine and a formal synthesis of (+)-epibatidine

Adrian Hall,Patrick D. Bailey,David C. Rees,Georgina M. Rosair,Richard H. Wightman J. Chem. Soc. Perkin Trans. 1 2000 329
3. Water-soluble arene ruthenium catalysts containing sulfonated diamine ligands for asymmetric transfer hydrogenation of α-aryl ketones and imines in aqueous solution

Jér?me Canivet,Georg Süss-Fink Green Chem. 2007 9 391
4. Post-synthetic modification of metal–organic frameworks for chiral gas chromatography

Wen-Ting Kou,Cheng-Xiong Yang,Xiu-Ping Yan J. Mater. Chem. A 2018 6 17861
5. Diastereoselectivity and assignment of absolute stereochemistry in the aza-Diels–Alder reaction of a sulfonylimino acetate with 1-methoxy-3-trimethylsilyloxybuta-1,3-diene

Andrew K. McFarlane,Gareth Thomas,Andrew Whiting J. Chem. Soc. Perkin Trans. 1 1995 2803

Additional information on (1R)-(-)-10-Camphorsulfonyl Chloride

Comprehensive Guide to (1R)-(-)-10-Camphorsulfonyl Chloride (CAS No. 39262-22-1): Properties, Applications, and Innovations

(1R)-(-)-10-Camphorsulfonyl Chloride (CAS No. 39262-22-1) is a highly specialized chiral reagent widely utilized in asymmetric synthesis and pharmaceutical research. This compound, derived from camphor, exhibits unique stereochemical properties that make it invaluable for constructing enantiomerically pure molecules. Its sulfonyl chloride functional group enables efficient derivatization, particularly in peptide coupling reactions and catalytic transformations. Researchers frequently search for "chiral auxiliaries," "asymmetric catalysis," and "enantioselective synthesis"—key terms where this compound plays a pivotal role.

The growing demand for optically active intermediates in drug development has spotlighted (1R)-(-)-10-Camphorsulfonyl Chloride. With the pharmaceutical industry prioritizing "green chemistry" and "sustainable synthesis," this reagent's recyclability and minimal waste generation align with modern trends. Recent studies highlight its utility in synthesizing biologically active molecules, addressing popular queries like "how to improve enantiomeric excess" and "best reagents for chiral resolution."

From a structural perspective, the compound's camphor backbone provides rigidity, enhancing stereocontrol in reactions. Its CAS No. 39262-22-1 is frequently referenced in patent literature for applications ranging from kinetic resolution to ligand design. Analytical techniques such as HPLC and NMR are commonly employed to verify its purity, a topic often searched alongside "chiral purity analysis."

Innovations in organocatalysis have further expanded the scope of (1R)-(-)-10-Camphorsulfonyl Chloride. For instance, its derivatives are explored in "C-H activation" reactions—a trending research area. The compound's compatibility with flow chemistry systems also answers industry demands for scalable and automated synthesis, addressing searches like "continuous flow chiral synthesis."

Safety and handling protocols for this reagent emphasize its stability under inert conditions, a detail crucial for laboratories focusing on "air-sensitive reagents." Storage recommendations typically include anhydrous environments and low temperatures, topics frequently queried by synthetic chemists.

In summary, (1R)-(-)-10-Camphorsulfonyl Chloride (CAS No. 39262-22-1) bridges fundamental research and industrial applications, driven by its stereoselectivity and adaptability. Its relevance to "drug discovery" and "catalysis" ensures continued interest, while advancements in sustainable methodologies position it as a future-proof tool for chemists worldwide.

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