Cas no 389573-45-9 (ent-Paroxol)
ent-Paroxol Chemical and Physical Properties
Names and Identifiers
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- ((3R,4S)-4-(4-Fluorophenyl)-1-methylpiperidin-3-yl)methanol
- ent-Paroxol
- (-)-trans-4-(4'-Fluorophenyl)-3-hydroxymethyl-N-methyl-piperidine
- ent-Paroxo
- [(3R,4S)-4-(4-Fluorophenyl)-1-methylpiperidinyl]methanol
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- Inchi： 1S/C13H18FNO/c1-15-7-6-13(11(8-15)9-16)10-2-4-12(14)5-3-10/h2-5,11,13,16H,6-9H2,1H3/t11-,13-/m1/s1
- InChI Key： CXRHUYYZISIIMT-DGCLKSJQSA-N
- SMILES： FC1C=CC(=CC=1)[C@H]1CCN(C)C[C@@H]1CO
Computed Properties
- Exact Mass: 223.13700
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 16
- Rotatable Bond Count: 2
Experimental Properties
- Melting Point: 98-100°C
- PSA: 23.47000
- LogP: 1.79120
ent-Paroxol Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM179522-1g |
((3R,4S)-4-(4-fluorophenyl)-1-methylpiperidin-3-yl)methanol |
389573-45-9 | 95% | 1g |
$430 | 2021-08-05 | |
| Alichem | A129003704-1g |
((3R,4S)-4-(4-Fluorophenyl)-1-methylpiperidin-3-yl)methanol |
389573-45-9 | 95% | 1g |
$401.76 | 2023-09-02 | |
| TRC | P205805-50mg |
ent-Paroxol |
389573-45-9 | 50mg |
$ 110.00 | 2023-04-15 | ||
| TRC | P205805-100mg |
ent-Paroxol |
389573-45-9 | 100mg |
$ 193.00 | 2023-04-15 | ||
| TRC | P205805-250mg |
ent-Paroxol |
389573-45-9 | 250mg |
$ 391.00 | 2023-04-15 | ||
| TRC | P205805-500mg |
ent-Paroxol |
389573-45-9 | 500mg |
$ 735.00 | 2023-04-15 | ||
| TRC | P205805-1g |
ent-Paroxol |
389573-45-9 | 1g |
$ 1303.00 | 2023-04-15 | ||
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | R854008-50mg |
[(3R,4S)-4-(4-Fluorophenyl)-1-methylpiperidinyl]methanol |
389573-45-9 | ≥95% | 50mg |
￥386.00 | 2022-10-10 | |
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | R854008-250mg |
[(3R,4S)-4-(4-Fluorophenyl)-1-methylpiperidinyl]methanol |
389573-45-9 | ≥95% | 250mg |
￥1,386.00 | 2022-10-10 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | R32480-1g |
(-)-trans-4-(4'-Fluorophenyl)-3-hydroxymethyl-N-methyl-piperidine |
389573-45-9 | 1g |
￥5188.0 | 2021-09-08 |
ent-Paroxol Related Literature
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Sowmyalakshmi Venkataraman RSC Adv., 2015,5, 73807-73813
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Zhixia Liu,Tingjian Chen,Floyd E. Romesberg Chem. Sci., 2017,8, 8179-8182
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Bin Han,Yasuo Shimizu,Gabriele Seguini,Celia Castro,Gérard Ben Assayag,Koji Inoue,Yasuyoshi Nagai,Sylvie Schamm-Chardon,Michele Perego RSC Adv., 2016,6, 3617-3622
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Tao Wang,Yangyang Liu,Yue Deng,Hongbo Fu,Jianmin Chen Environ. Sci.: Nano, 2018,5, 1821-1833
Additional information on ent-Paroxol
Ent-Paroxol: A Comprehensive Overview
Ent-Paroxol, also known by its CAS number 389573-45-9, is a natural product derived from the extraction of various plant species. This compound has garnered significant attention in the biomedical field due to its unique chemical structure and potential applications in pharmacology and medicine.
Recent studies have highlighted the role of ent-Paroxol in anti-inflammatory and antioxidant activities. These properties make it a promising candidate for the development of therapeutic agents against chronic inflammatory diseases such as arthritis, cardiovascular disorders, and neurodegenerative conditions.
Research conducted in 2023 has further elucidated the mechanism by which ent-Paroxol exerts its effects. It was found that this compound modulates key signaling pathways, including the NF-κB pathway and the Nrf2 antioxidant response pathway, thereby providing a robust defense against oxidative stress and inflammation.
Another area of interest is the potential of ent-Paroxol in oncology. Preclinical studies have demonstrated its ability to induce apoptosis in various cancer cell lines, particularly in breast and liver cancer models. This has opened up new avenues for exploring its use as an adjunct or alternative treatment in cancer therapy.
Furthermore, advancements in ent-Paroxol synthesis have enabled researchers to produce this compound in larger quantities, facilitating preclinical trials and paving the way for future clinical studies. The development of efficient extraction methods from natural sources has also contributed to its availability for scientific research.
In summary, ent-Paroxol stands as a remarkable compound with diverse biological activities that hold great promise in biomedical research and therapeutic applications. Ongoing studies aim to further characterize its mechanisms of action and explore its potential in treating a wide range of diseases.
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