Cas no 387350-79-0 (Benzenesulfonamide,N-cyclopropyl-N-4-piperidinyl-3-(trifluoromethyl)-)

Benzenesulfonamide, N-cyclopropyl-N-4-piperidinyl-3-(trifluoromethyl)-, is a specialized sulfonamide derivative featuring a cyclopropyl-piperidinyl substitution pattern and a trifluoromethyl group at the 3-position of the benzene ring. This structural configuration imparts unique physicochemical properties, including enhanced lipophilicity and metabolic stability, making it a valuable intermediate in medicinal chemistry and pharmaceutical research. The trifluoromethyl group contributes to improved binding affinity and selectivity in target interactions, while the cyclopropyl and piperidinyl moieties offer steric and electronic modulation. Its well-defined synthesis and high purity make it suitable for applications in drug discovery, particularly in the development of enzyme inhibitors and receptor modulators.
Benzenesulfonamide,N-cyclopropyl-N-4-piperidinyl-3-(trifluoromethyl)- structure
387350-79-0 structure
Product Name:Benzenesulfonamide,N-cyclopropyl-N-4-piperidinyl-3-(trifluoromethyl)-
CAS No:387350-79-0
MF:C15H19F3N2O2S
MW:348.383773088455
MDL:MFCD01568000
CID:298726
PubChem ID:2773944
Update Time:2025-05-27

Benzenesulfonamide,N-cyclopropyl-N-4-piperidinyl-3-(trifluoromethyl)- Chemical and Physical Properties

Names and Identifiers

    • Benzenesulfonamide,N-cyclopropyl-N-4-piperidinyl-3-(trifluoromethyl)-
    • N-Cyclopropyl-N-(4-piperidinyl)-3-(trifluoromethyl)benzenesulfonamide
    • N-Cyclopropyl-N-(piperidin-4-yl)-3-(trifluoromethyl)benzenesulphonamide
    • AC1MCNP4
    • AC1Q4ISX
    • N-cyclopropyl-N-(piperidin-4-yl)-3-(trifluoromethyl)benzenesulfonamide
    • N-cyclopropyl-N-piperidin-4-yl-3-trifluoromethyl-benzenesulfonamide
    • Peakdale1_001258
    • SureCN3485825
    • 387350-79-0
    • Z1741960470
    • SR-01000387773
    • HMS521J04
    • A824256
    • MFCD01568000
    • N-cyclopropyl-N-piperidin-4-yl-3-(trifluoromethyl)benzenesulfonamide
    • N-cyclopropyl-N-piperidin-4-yl-3-trifluoromethyl-benzene sulfonamide
    • SCHEMBL3485825
    • SR-01000387773-1
    • N-cyclopropyl-N-(piperidin-4-yl)-3-(trifluoromethyl)benzene-1-sulfonamide
    • PS-7000
    • DTXSID30378789
    • AKOS015840782
    • N-cyclopropyl-N-(piperidin-4-yl)-3-trifluoromethylbenzenesulfonamide
    • N-cyclopropyl-N-piperidin-4-yl-3-trifluoromethylbenzenesulfonamide
    • MDL： MFCD01568000
    • Inchi： 1S/C15H19F3N2O2S/c16-15(17,18)11-2-1-3-14(10-11)23(21,22)20(12-4-5-12)13-6-8-19-9-7-13/h1-3,10,12-13,19H,4-9H2
    • InChI Key： NQBHDSLGAKITFX-UHFFFAOYSA-N
    • SMILES： S(C1C=CC=C(C(F)(F)F)C=1)(N(C1CCNCC1)C1CC1)(=O)=O

Computed Properties

  • Exact Mass: 348.11207
  • Monoisotopic Mass: 348.112
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 23
  • Rotatable Bond Count: 5
  • Complexity: 508
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 2.6
  • Topological Polar Surface Area: 57.8?2

Experimental Properties

  • Density: 1.39
  • Melting Point: >195°C
  • Boiling Point: 437.9°Cat760mmHg
  • Flash Point: 218.6°C
  • Refractive Index: 1.561
  • PSA: 49.41

Benzenesulfonamide,N-cyclopropyl-N-4-piperidinyl-3-(trifluoromethyl)- Security Information

  • Hazardous Material Identification： Xi

Benzenesulfonamide,N-cyclopropyl-N-4-piperidinyl-3-(trifluoromethyl)- Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Fluorochem
010570-1g
N-Cyclopropyl-N-(4-piperidinyl)-3-(trifluoromethyl)benzenesulfonamide
 387350-79-0 97%
1g
 ￡45.00 2022-03-01
Fluorochem
010570-5g
N-Cyclopropyl-N-(4-piperidinyl)-3-(trifluoromethyl)benzenesulfonamide
 387350-79-0 97%
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 ￡215.00 2022-03-01
Apollo Scientific
PC9239-1g
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 387350-79-0 95+%
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 ￡120.00 2025-02-22
SHANG HAI XIAN DING Biotechnology Co., Ltd.
006958-1g
N-Cyclopropyl-N-(4-piperidinyl)-3-(trifluoromethyl)benzenesulfonamide
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 1283.0CNY 2021-07-13
SHANG HAI XIAN DING Biotechnology Co., Ltd.
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SHANG HAI XIAN DING Biotechnology Co., Ltd.
006958-1g
N-Cyclopropyl-N-(4-piperidinyl)-3-(trifluoromethyl)benzenesulfonamide
 387350-79-0
1g
 1283CNY 2021-05-07
SHANG HAI XIAN DING Biotechnology Co., Ltd.
006958-5g
N-Cyclopropyl-N-(4-piperidinyl)-3-(trifluoromethyl)benzenesulfonamide
 387350-79-0
5g
 4551CNY 2021-05-07
Chemenu
CM519435-1g
N-Cyclopropyl-N-(piperidin-4-yl)-3-(trifluoromethyl)benzenesulfonamide
 387350-79-0 95%
1g
 $61 2022-09-01
Chemenu
CM519435-5g
N-Cyclopropyl-N-(piperidin-4-yl)-3-(trifluoromethyl)benzenesulfonamide
 387350-79-0 95%
5g
 $251 2022-09-01
abcr
AB170005-1 g
N-Cyclopropyl-N-piperidin-4-yl-3-(trifluoromethyl)benzenesulfonamide; .
 387350-79-0
1g
 €120.10 2023-05-07

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