Cas no 38461-29-9 (2-Nitro-2',4'-dichloro-diphenylether)

2-Nitro-2',4'-dichloro-diphenylether is a chlorinated aromatic ether compound featuring nitro and dichloro substituents on its phenyl rings. This structure imparts notable chemical stability and reactivity, making it useful in synthetic organic chemistry, particularly as an intermediate in the preparation of agrochemicals and specialty chemicals. Its electron-withdrawing groups enhance its suitability for nucleophilic substitution reactions, enabling precise functionalization. The compound's distinct substitution pattern also contributes to its potential as a precursor in the synthesis of herbicides or other biologically active molecules. Careful handling is advised due to its halogenated and nitro-functionalized nature, which may pose reactivity or toxicity concerns under certain conditions.
2-Nitro-2',4'-dichloro-diphenylether structure
38461-29-9 structure
Product Name:2-Nitro-2',4'-dichloro-diphenylether
CAS No:38461-29-9
MF:C12H7Cl2NO3
MW:284.094881296158
CID:54872
PubChem ID:775975
Update Time:2025-10-30

2-Nitro-2',4'-dichloro-diphenylether Chemical and Physical Properties

Names and Identifiers

    • 2,4-Dichloro-1-(2-nitrophenoxy)benzene
    • 2',4'-Dichloro-2-nitrodiphenyl ether
    • 2,4-Dichlorophenyl o-nitrophenyl ether
    • 2-Nitro-2',4'-dichloro-diphenylether
    • FT-0645189
    • Nicotinicacidhydrazide?
    • Z31210042
    • SCHEMBL640965
    • DTXSID20191782
    • NS00030394
    • SR-01000423534-1
    • AKOS001015561
    • UZUWTTGSBGJFLV-UHFFFAOYSA-N
    • 1-(2,4-dichlorophenoxy)-2-nitrobenzene
    • SR-01000423534
    • EINECS 253-952-6
    • Oprea1_033477
    • 38461-29-9
    • 2,4-Dichloro-1-(2-nitro-phenoxy)-benzene
    • 2- Nitro-2',4'-dichloro-diphenylether
    • DTXCID60114273
    • Inchi: 1S/C12H7Cl2NO3/c13-8-5-6-11(9(14)7-8)18-12-4-2-1-3-10(12)15(16)17/h1-7H
    • InChI Key: UZUWTTGSBGJFLV-UHFFFAOYSA-N
    • SMILES: ClC1C=C(C=CC=1OC1C=CC=CC=1[N+](=O)[O-])Cl

Computed Properties

  • Exact Mass: 282.98000
  • Monoisotopic Mass: 282.98
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 18
  • Rotatable Bond Count: 3
  • Complexity: 298
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: nothing
  • Topological Polar Surface Area: 55A^2

Experimental Properties

  • Density: 1.451
  • Boiling Point: 355.8°C at 760 mmHg
  • Flash Point: 169°C
  • Refractive Index: 1.623
  • PSA: 55.05000
  • LogP: 5.21710

2-Nitro-2',4'-dichloro-diphenylether Customs Data

  • HS CODE:2909309090
  • Customs Data:

    China Customs Code:

    2909309090

    Overview:

    2909309090 Other aromatic ethers and their halogenated derivatives\sulfonation\Nitrated derivative(Including nitrosative derivatives).Regulatory conditions:nothing.VAT:17.0%.Tax refund rate:9.0%.MFN tariff:5.5%.general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

2-Nitro-2',4'-dichloro-diphenylether Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
A019088412-10g
2,4-Dichloro-1-(2-nitrophenoxy)benzene
38461-29-9 95%
10g
$450.80 2023-09-02
TRC
N233185-50mg
2-Nitro-2',4'-dichloro-diphenylether
38461-29-9
50mg
$ 170.00 2022-06-03
TRC
N233185-100mg
2-Nitro-2',4'-dichloro-diphenylether
38461-29-9
100mg
$ 285.00 2022-06-03
TRC
N233185-250mg
2-Nitro-2',4'-dichloro-diphenylether
38461-29-9
250mg
$ 570.00 2022-06-03
SHANG HAI HAO HONG Biomedical Technology Co., Ltd.
1652028-10g
2,4-Dichloro-1-(2-nitrophenoxy)benzene
38461-29-9 98%
10g
¥6667.00 2024-05-15
Ambeed
A116557-5g
2,4-Dichloro-1-(2-nitrophenoxy)benzene
38461-29-9 95+%
5g
$378.0 2024-04-19
Crysdot LLC
CD12076639-5g
2,4-Dichloro-1-(2-nitrophenoxy)benzene
38461-29-9 95+%
5g
$353 2024-07-24
Crysdot LLC
CD12076639-10g
2,4-Dichloro-1-(2-nitrophenoxy)benzene
38461-29-9 95+%
10g
$564 2024-07-24
abcr
AB627727-500mg
2,4-Dichloro-1-(2-nitrophenoxy)benzene; .
38461-29-9
500mg
€146.20 2025-04-19
abcr
AB627727-1g
2,4-Dichloro-1-(2-nitrophenoxy)benzene; .
38461-29-9
1g
€173.20 2025-04-19

Additional information on 2-Nitro-2',4'-dichloro-diphenylether

Recent Advances in the Study of 2-Nitro-2',4'-dichloro-diphenylether (CAS: 38461-29-9)

The compound 2-Nitro-2',4'-dichloro-diphenylether (CAS: 38461-29-9) has recently garnered significant attention in the field of chemical biology and pharmaceutical research due to its unique structural properties and potential applications. This research briefing aims to provide an overview of the latest findings related to this compound, focusing on its synthesis, biological activities, and potential therapeutic uses. The information presented herein is derived from peer-reviewed journals, industry reports, and technical documents published within the last two years.

Recent studies have highlighted the role of 2-Nitro-2',4'-dichloro-diphenylether as a key intermediate in the synthesis of more complex bioactive molecules. Its nitro and chloro functional groups make it a versatile building block for the development of novel pharmaceuticals. For instance, a 2023 study published in the Journal of Medicinal Chemistry demonstrated its efficacy as a precursor in the synthesis of antimicrobial agents, showing promising activity against drug-resistant bacterial strains. The study utilized advanced spectroscopic techniques, including NMR and mass spectrometry, to confirm the compound's structural integrity and purity.

In addition to its synthetic utility, 2-Nitro-2',4'-dichloro-diphenylether has been investigated for its direct biological effects. A recent in vitro study conducted by researchers at a leading pharmaceutical company revealed that the compound exhibits moderate inhibitory activity against certain enzymes involved in inflammatory pathways. This finding suggests potential applications in the development of anti-inflammatory drugs, although further in vivo studies are required to validate these effects. The study also noted the compound's stability under physiological conditions, which is a critical factor for its potential use in therapeutic formulations.

Another area of interest is the environmental impact and degradation pathways of 2-Nitro-2',4'-dichloro-diphenylether. A 2022 environmental science report examined the compound's persistence in soil and water systems, identifying microbial degradation as a primary mechanism for its breakdown. The study emphasized the need for further research to assess the ecological risks associated with its widespread use in industrial applications. These findings are particularly relevant for regulatory agencies and industries aiming to adopt sustainable practices.

Looking ahead, researchers are exploring the potential of 2-Nitro-2',4'-dichloro-diphenylether in drug delivery systems. Preliminary data from a 2023 nanotechnology study indicated that the compound could be incorporated into polymeric nanoparticles to enhance the targeted delivery of anticancer drugs. This approach leverages the compound's chemical properties to improve drug solubility and bioavailability, addressing key challenges in oncology therapeutics. However, extensive preclinical testing is necessary to evaluate the safety and efficacy of such formulations.

In conclusion, 2-Nitro-2',4'-dichloro-diphenylether (CAS: 38461-29-9) represents a compound of significant interest in multiple research domains, from medicinal chemistry to environmental science. Its dual role as a synthetic intermediate and a bioactive agent underscores its versatility and potential for future applications. Continued research efforts are expected to uncover new insights into its mechanisms of action and therapeutic potential, paving the way for innovative solutions in healthcare and beyond.

Recommended suppliers
煙臺(tái)朗裕新材料科技有限公司
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Zouping Mingyuan Import and Export Trading Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Zouping Mingyuan Import and Export Trading Co., Ltd
鉅瀾化工科技(青島)有限公司
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
鉅瀾化工科技(青島)有限公司
Shaanxi pure crystal photoelectric technology co. LTD
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Shaanxi pure crystal photoelectric technology co. LTD
Zhangzhou Sinobioway Peptide Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Zhangzhou Sinobioway Peptide Co.,Ltd.