Cas no 3840-66-2 (2-Chloro-N-2-(4-chlorophenyl)ethylacetamide)

2-Chloro-N-2-(4-chlorophenyl)ethylacetamide is a chloro-substituted acetamide derivative with potential applications in organic synthesis and pharmaceutical research. Its structure features a 4-chlorophenethyl group linked to an acetamide moiety with a chloro substituent at the α-position, enhancing its reactivity in nucleophilic substitution and condensation reactions. This compound is valued for its role as an intermediate in the synthesis of more complex molecules, particularly in agrochemical and medicinal chemistry. Its dual chloro functionality contributes to its stability and selectivity in targeted reactions. Proper handling and storage under inert conditions are recommended due to its sensitivity to moisture and light.
2-Chloro-N-2-(4-chlorophenyl)ethylacetamide structure
3840-66-2 structure
Product Name:2-Chloro-N-2-(4-chlorophenyl)ethylacetamide
CAS No:3840-66-2
MF:C10H11Cl2NO
MW:232.106440782547
MDL:MFCD03966871
CID:296609
PubChem ID:2392274
Update Time:2025-06-14

2-Chloro-N-2-(4-chlorophenyl)ethylacetamide Chemical and Physical Properties

Names and Identifiers

    • 2-Chloro-N-(4-chlorophenethyl)acetamide
    • 2-chloro-N-[2-(4-chlorophenyl)ethyl]acetamide
    • Acetamide,2-chloro-N-[2-(4-chlorophenyl)ethyl]-
    • 2-Chloro-N-[2-(4-chloro-phenyl)-ethyl]-acetamide
    • SCHEMBL5574769
    • EN300-02030
    • CS-0307565
    • RVQXTGCQLPYVQI-UHFFFAOYSA-N
    • DTXSID80368433
    • MFCD03966871
    • LS-06271
    • AKOS005715807
    • 3840-66-2
    • Z56891264
    • 2-Chloro-N-2-(4-chlorophenyl)ethylacetamide
    • MDL: MFCD03966871
    • Inchi: 1S/C10H11Cl2NO/c11-7-10(14)13-6-5-8-1-3-9(12)4-2-8/h1-4H,5-7H2,(H,13,14)
    • InChI Key: RVQXTGCQLPYVQI-UHFFFAOYSA-N
    • SMILES: ClC1C=CC(=CC=1)CCNC(CCl)=O

Computed Properties

  • Exact Mass: 231.02200
  • Monoisotopic Mass: 231.0217694g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 5
  • Complexity: 179
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.7
  • Topological Polar Surface Area: 29.1?2

Experimental Properties

  • PSA: 29.10000
  • LogP: 2.62840

2-Chloro-N-2-(4-chlorophenyl)ethylacetamide Customs Data

  • HS CODE:2924299090
  • Customs Data:

    China Customs Code:

    2924299090

    Overview:

    2924299090. Other cyclic amides(Including cyclic carbamates)(Including their derivatives as well as their salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, packing

    Summary:

    2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

2-Chloro-N-2-(4-chlorophenyl)ethylacetamide Pricemore >>

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2-Chloro-N-2-(4-chlorophenyl)ethylacetamide Related Literature

Additional information on 2-Chloro-N-2-(4-chlorophenyl)ethylacetamide

Comprehensive Overview of 2-Chloro-N-2-(4-chlorophenyl)ethylacetamide (CAS No. 3840-66-2)

2-Chloro-N-2-(4-chlorophenyl)ethylacetamide, identified by its CAS No. 3840-66-2, is a specialized organic compound widely utilized in agrochemical and pharmaceutical research. This chlorinated acetamide derivative has garnered significant attention due to its unique structural properties and potential applications. The compound's molecular formula, C10H11Cl2NO, highlights its dual chloro-functional groups, which contribute to its reactivity and versatility in synthetic chemistry.

In recent years, the demand for chlorinated acetamide derivatives has surged, driven by their role in developing novel crop protection agents. Researchers are particularly interested in 2-Chloro-N-2-(4-chlorophenyl)ethylacetamide for its potential as an intermediate in herbicide formulations. With global agriculture facing challenges like pesticide resistance and environmental sustainability, this compound's relevance continues to grow. Its mechanism of action, often linked to inhibiting weed growth, aligns with the industry's shift toward eco-friendly agrochemicals.

The synthesis of CAS No. 3840-66-2 typically involves the reaction of 4-chlorophenethylamine with chloroacetyl chloride under controlled conditions. This process yields a high-purity product, essential for ensuring consistency in downstream applications. Analytical techniques such as HPLC and GC-MS are commonly employed to verify the compound's purity, addressing the increasing consumer focus on quality control in chemical production.

Beyond agrochemicals, 2-Chloro-N-2-(4-chlorophenyl)ethylacetamide has shown promise in pharmaceutical research. Its structural motif is being explored for designing bioactive molecules targeting neurological and metabolic disorders. This aligns with trending searches like "chloroacetamide drug discovery" and "sustainable chemical intermediates," reflecting broader scientific and industrial interests.

From an environmental standpoint, the biodegradability and toxicity profile of 3840-66-2 are critical considerations. Recent studies emphasize the need for green chemistry alternatives, prompting innovations in catalytic processes to minimize waste. Regulatory frameworks such as REACH and EPA guidelines further underscore the importance of responsible handling and disposal, topics frequently queried by professionals in the field.

In summary, 2-Chloro-N-2-(4-chlorophenyl)ethylacetamide (CAS No. 3840-66-2) represents a multifaceted compound with applications spanning agriculture and medicine. Its synthesis, properties, and evolving uses resonate with contemporary themes like sustainable chemistry and precision agriculture, making it a subject of enduring relevance in scientific discourse.

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