Cas no 380482-31-5 (3,4-Diethoxybenzohydrazide)

3,4-Diethoxybenzohydrazide is a hydrazide derivative characterized by its diethoxy-substituted aromatic ring, which enhances its reactivity and solubility in organic solvents. This compound is commonly employed as an intermediate in organic synthesis, particularly in the preparation of heterocyclic compounds, pharmaceuticals, and agrochemicals. Its hydrazide functional group allows for versatile transformations, including condensation reactions to form hydrazones or further derivatization into active pharmacophores. The ethoxy substituents contribute to improved stability and electronic properties, making it a valuable building block in medicinal chemistry. Suitable for controlled reactions, it offers consistent purity and reliable performance in synthetic applications.
3,4-Diethoxybenzohydrazide structure
3,4-Diethoxybenzohydrazide structure
Product Name:3,4-Diethoxybenzohydrazide
CAS No:380482-31-5
MF:C11H16N2O3
MW:224.256342887878
MDL:MFCD01310808
CID:303926
PubChem ID:2758233
Update Time:2025-10-28

3,4-Diethoxybenzohydrazide Chemical and Physical Properties

Names and Identifiers

    • Benzoicacid, 3,4-diethoxy-, hydrazide
    • 3,4-DIETHOXYBENZHYDRAZIDE
    • 3,4-diethoxybenzohydrazide
    • DTXSID80374231
    • VS-06315
    • AKOS000150797
    • FT-0676389
    • SCHEMBL17141817
    • MFCD01310808
    • 380482-31-5
    • A823992
    • CS-0314062
    • 3,4-Diethoxybenzohydrazide, AldrichCPR
    • STK463044
    • BBL017598
    • DB-021877
    • ALBB-002699
    • 3,4-Diethoxybenzohydrazide
    • MDL: MFCD01310808
    • Inchi: 1S/C11H16N2O3/c1-3-15-9-6-5-8(11(14)13-12)7-10(9)16-4-2/h5-7H,3-4,12H2,1-2H3,(H,13,14)
    • InChI Key: UXWHTJPMGMMDNV-UHFFFAOYSA-N
    • SMILES: O(CC)C1C=C(C(NN)=O)C=CC=1OCC

Computed Properties

  • Exact Mass: 224.11600
  • Monoisotopic Mass: 224.11609238g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 6
  • Complexity: 223
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.4
  • Topological Polar Surface Area: 73.6?2

Experimental Properties

  • Melting Point: 164-166°C
  • PSA: 73.58000
  • LogP: 2.17870

3,4-Diethoxybenzohydrazide Security Information

  • Hazard Category Code: 20/21/22-36-22
  • Safety Instruction: 36-26
  • Hazardous Material Identification: Xi
  • HazardClass:IRRITANT
  • Risk Phrases:R20/21/22
  • Safety Term:S36

3,4-Diethoxybenzohydrazide Customs Data

  • HS CODE:2928000090
  • Customs Data:

    China Customs Code:

    2928000090

    Overview:

    2928000090 Other hydrazine(Hydrazine)And chlorhexidine(hydroxylamine)Organic derivatives of.Regulatory conditions:nothing.VAT:17.0%.Tax refund rate:9.0%.MFN tariff:6.5%.general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

3,4-Diethoxybenzohydrazide Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
SHANG HAI XIAN DING Biotechnology Co., Ltd.
005654-1g
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TRC
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abcr
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1g
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abcr
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€174.00 2025-02-27

Additional information on 3,4-Diethoxybenzohydrazide

Professional Introduction to 3,4-Diethoxybenzohydrazide (CAS No. 380482-31-5)

3,4-Diethoxybenzohydrazide, a compound with the chemical formula C10H14N2O2, is a significant intermediate in organic synthesis and pharmaceutical research. This compound is characterized by its 3,4-diethoxybenzohydrazide structure, which makes it a valuable building block for various pharmacologically active molecules. The CAS no. 380482-31-5 uniquely identifies this substance, ensuring precise classification and handling in laboratory and industrial settings.

The 3,4-diethoxybenzohydrazide moiety is particularly interesting due to its potential applications in the synthesis of heterocyclic compounds and bioactive molecules. Recent advancements in medicinal chemistry have highlighted its role in developing novel therapeutic agents. For instance, derivatives of this compound have been explored for their antimicrobial and anti-inflammatory properties. The presence of two ethoxy groups enhances the compound's solubility and reactivity, making it a versatile precursor in synthetic pathways.

In the realm of drug discovery, the 3,4-diethoxybenzohydrazide scaffold has been utilized to create molecules that interact with specific biological targets. Studies have demonstrated its efficacy in modulating enzyme activity and receptor binding. One notable area of research involves its application in the development of kinase inhibitors, which are crucial for treating cancers and inflammatory diseases. The structural flexibility of 3,4-diethoxybenzohydrazide allows chemists to modify its core framework, leading to a diverse array of pharmacophores.

The synthesis of 3,4-diethoxybenzohydrazide typically involves multi-step reactions starting from readily available aromatic precursors. Advanced synthetic techniques, such as palladium-catalyzed cross-coupling reactions, have improved the efficiency and yield of its production. These methods align with the growing emphasis on sustainable chemistry practices, reducing waste and energy consumption without compromising purity.

Recent research has also explored the role of 3,4-diethoxybenzohydrazide in material science. Its ability to form stable complexes with metal ions has led to innovative applications in catalysis and sensor technology. The compound's unique electronic properties make it suitable for use in organic semiconductors and light-emitting diodes (LEDs). Such applications underscore the broad utility of 3,4-diethoxybenzohydrazide, extending beyond traditional pharmaceuticals into cutting-edge technological domains.

The safety profile of 3,4-diethoxybenzohydrazide is another critical aspect that has been thoroughly investigated. While it is not classified as a hazardous substance under standard regulatory guidelines, proper handling procedures must be followed to ensure worker safety. Laboratory protocols emphasize controlled environments and personal protective equipment (PPE) to mitigate any potential risks associated with its handling.

In conclusion, 3,4-Diethoxybenzohydrazide (CAS no. 380482-31-5) represents a fascinating compound with extensive applications in pharmaceuticals and material science. Its structural features enable diverse chemical modifications, making it a cornerstone in synthetic chemistry research. As scientific understanding progresses, the potential uses of this compound are likely to expand further, driving innovation across multiple scientific disciplines.

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