Cas no 380378-95-0 (6-Chloro-N-cyclopropyl-3-nitropyridin-2-amine)
6-Chloro-N-cyclopropyl-3-nitropyridin-2-amine is a heterocyclic compound featuring a pyridine core substituted with chloro, nitro, and cyclopropylamino functional groups. Its structural properties make it a valuable intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. The presence of both electron-withdrawing (nitro, chloro) and electron-donating (cyclopropylamino) groups enhances its reactivity in nucleophilic aromatic substitution and cross-coupling reactions. This compound exhibits stability under standard conditions, facilitating handling and storage. Its versatility in derivatization allows for the synthesis of diverse bioactive molecules, making it a useful building block in medicinal chemistry research.
380378-95-0 structure
Product Name:6-Chloro-N-cyclopropyl-3-nitropyridin-2-amine
CAS No:380378-95-0
MF:C8H8ClN3O2
MW:213.621020317078
MDL:MFCD11047134
CID:1035886
PubChem ID:18466602
Update Time:2025-06-07
6-Chloro-N-cyclopropyl-3-nitropyridin-2-amine Chemical and Physical Properties
Names and Identifiers
-
- 6-Chloro-N-cyclopropyl-3-nitropyridin-2-amine
- DB-307106
- G54945
- AKOS009170718
- SCHEMBL5742514
- DTXSID50594121
- 380378-95-0
- 6-chloro-2-(cyclopropylamino)-3-nitropyridine
- FYIAEAAQBSHDPC-UHFFFAOYSA-N
- EN300-26292080
-
- MDL: MFCD11047134
- Inchi: 1S/C8H8ClN3O2/c9-7-4-3-6(12(13)14)8(11-7)10-5-1-2-5/h3-5H,1-2H2,(H,10,11)
- InChI Key: FYIAEAAQBSHDPC-UHFFFAOYSA-N
- SMILES: ClC1=CC=C(C(=N1)NC1CC1)[N+](=O)[O-]
Computed Properties
- Exact Mass: 213.03064
- Monoisotopic Mass: 213.0305042g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 14
- Rotatable Bond Count: 3
- Complexity: 229
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 3.1
- Topological Polar Surface Area: 70.7?2
Experimental Properties
- PSA: 68.06
6-Chloro-N-cyclopropyl-3-nitropyridin-2-amine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Matrix Scientific | 222035-500mg |
6-Chloro-N-cyclopropyl-3-nitropyridin-2-amine, 95% min |
380378-95-0 | 95% | 500mg |
$729.00 | 2023-09-06 | |
| Matrix Scientific | 222035-1g |
6-Chloro-N-cyclopropyl-3-nitropyridin-2-amine, 95% min |
380378-95-0 | 95% | 1g |
$1315.00 | 2023-09-06 | |
| Chemenu | CM171685-1g |
6-chloro-N-cyclopropyl-3-nitropyridin-2-amine |
380378-95-0 | 95% | 1g |
$729 | 2021-08-05 | |
| Alichem | A029184484-1g |
6-Chloro-N-cyclopropyl-3-nitropyridin-2-amine |
380378-95-0 | 95% | 1g |
$678.24 | 2023-09-02 | |
| Chemenu | CM171685-1g |
6-chloro-N-cyclopropyl-3-nitropyridin-2-amine |
380378-95-0 | 95% | 1g |
$609 | 2024-07-17 | |
| Aaron | AR00CSG0-50mg |
6-Chloro-N-cyclopropyl-3-nitropyridin-2-amine |
380378-95-0 | 95% | 50mg |
$179.00 | 2025-02-14 | |
| Aaron | AR00CSG0-100mg |
6-Chloro-N-cyclopropyl-3-nitropyridin-2-amine |
380378-95-0 | 95% | 100mg |
$256.00 | 2025-02-14 | |
| Aaron | AR00CSG0-250mg |
6-Chloro-N-cyclopropyl-3-nitropyridin-2-amine |
380378-95-0 | 95% | 250mg |
$355.00 | 2025-02-14 | |
| Aaron | AR00CSG0-500mg |
6-Chloro-N-cyclopropyl-3-nitropyridin-2-amine |
380378-95-0 | 95% | 500mg |
$636.00 | 2025-02-14 | |
| Aaron | AR00CSG0-1g |
6-Chloro-N-cyclopropyl-3-nitropyridin-2-amine |
380378-95-0 | 95% | 1g |
$811.00 | 2025-02-14 |
6-Chloro-N-cyclopropyl-3-nitropyridin-2-amine Related Literature
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Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
-
Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
-
Tengfei Yu,Yuehan Wu,Wei Li,Bin Li RSC Adv., 2014,4, 34134-34143
-
Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126
-
Liao Xiaoqing,Li Ruiyi,Li Zaijun,Sun Xiulan,Wang Zhouping,Liu Junkang New J. Chem., 2015,39, 5240-5248
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