Cas no 379254-61-2 (3-(hydrazinecarbonyl)-N-3-(trifluoromethyl)phenylbenzene-1-sulfonamide)

3-(Hydrazinecarbonyl)-N-3-(trifluoromethyl)phenylbenzene-1-sulfonamide is a specialized sulfonamide derivative featuring a hydrazinecarbonyl moiety and a trifluoromethylphenyl group. This compound is of interest in medicinal and agrochemical research due to its potential as a versatile intermediate in the synthesis of bioactive molecules. The presence of the trifluoromethyl group enhances lipophilicity and metabolic stability, while the hydrazinecarbonyl functionality offers reactivity for further derivatization. Its sulfonamide core provides a stable scaffold, making it suitable for applications in drug discovery and chemical biology. The compound’s structural features suggest utility in the development of enzyme inhibitors or receptor modulators, particularly in contexts requiring fluorine-containing pharmacophores.
3-(hydrazinecarbonyl)-N-3-(trifluoromethyl)phenylbenzene-1-sulfonamide structure
379254-61-2 structure
Product Name:3-(hydrazinecarbonyl)-N-3-(trifluoromethyl)phenylbenzene-1-sulfonamide
CAS No:379254-61-2
MF:C14H12F3N3O3S
MW:359.323592185974
CID:843421
PubChem ID:4464464
Update Time:2025-05-22

3-(hydrazinecarbonyl)-N-3-(trifluoromethyl)phenylbenzene-1-sulfonamide Chemical and Physical Properties

Names and Identifiers

    • 3-HYDRAZINOCARBONYL-N-(3-TRIFLUOROMETHYL-PHENYL)-BENZENESULFONAMIDE
    • 3-(hydrazinecarbonyl)-N-3-(trifluoromethyl)phenylbenzene-1-sulfonamide
    • G76235
    • Z71422216
    • CHEMBL1420902
    • 3-(hydrazinecarbonyl)-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide
    • 3-(hydrazinecarbonyl)-N-[3-(trifluoromethyl)phenyl]benzene-1-sulfonamide
    • HMS2764I21
    • C14H12F3N3O3S
    • SMR000364671
    • EN300-03756
    • J-512600
    • AKOS000116147
    • SR-01000068790-1
    • HMS1728E10
    • MLS000773838
    • SR-01000068790
    • 379254-61-2
    • 3-(Hydrazinecarbonyl)-N-(3-(trifluoromethyl)phenyl)benzenesulfonamide
    • MDL: MFCD03147276
    • Inchi: 1S/C14H12F3N3O3S/c15-14(16,17)10-4-2-5-11(8-10)20-24(22,23)12-6-1-3-9(7-12)13(21)19-18/h1-8,20H,18H2,(H,19,21)
    • InChI Key: KBKSVBWSGSNEDL-UHFFFAOYSA-N
    • SMILES: S(C1C=CC=C(C(NN)=O)C=1)(NC1C=CC=C(C(F)(F)F)C=1)(=O)=O

Computed Properties

  • Exact Mass: 359.05514691g/mol
  • Monoisotopic Mass: 359.05514691g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 24
  • Rotatable Bond Count: 6
  • Complexity: 548
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.9
  • Topological Polar Surface Area: 110?2

3-(hydrazinecarbonyl)-N-3-(trifluoromethyl)phenylbenzene-1-sulfonamide Pricemore >>

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Additional information on 3-(hydrazinecarbonyl)-N-3-(trifluoromethyl)phenylbenzene-1-sulfonamide

Comprehensive Overview of 3-(hydrazinecarbonyl)-N-3-(trifluoromethyl)phenylbenzene-1-sulfonamide (CAS No. 379254-61-2)

The compound 3-(hydrazinecarbonyl)-N-3-(trifluoromethyl)phenylbenzene-1-sulfonamide (CAS No. 379254-61-2) is a specialized organic molecule that has garnered significant attention in pharmaceutical and agrochemical research. Its unique structure, featuring a hydrazinecarbonyl moiety and a trifluoromethylphenyl group, makes it a valuable intermediate in the synthesis of bioactive compounds. Researchers are particularly interested in its potential applications due to the increasing demand for novel sulfonamide derivatives in drug discovery and material science.

In recent years, the scientific community has focused on the role of sulfonamide-based compounds in addressing global health challenges, such as antimicrobial resistance and chronic diseases. The presence of the trifluoromethyl group in 3-(hydrazinecarbonyl)-N-3-(trifluoromethyl)phenylbenzene-1-sulfonamide enhances its metabolic stability and bioavailability, making it a promising candidate for further development. This aligns with the growing trend of incorporating fluorinated compounds into modern therapeutics, as highlighted by recent advancements in medicinal chemistry.

The synthesis and characterization of CAS No. 379254-61-2 involve sophisticated techniques such as nuclear magnetic resonance (NMR) spectroscopy and high-performance liquid chromatography (HPLC). These methods ensure the purity and consistency of the compound, which is critical for its application in high-value industries. Additionally, the compound's hydrazinecarbonyl functionality offers versatility in chemical modifications, enabling researchers to explore its potential in creating targeted drug delivery systems and biocompatible materials.

From an industrial perspective, 3-(hydrazinecarbonyl)-N-3-(trifluoromethyl)phenylbenzene-1-sulfonamide is often discussed in the context of green chemistry and sustainable manufacturing. Companies are increasingly adopting eco-friendly synthesis routes to minimize environmental impact, and this compound's modular structure allows for optimization in this regard. Furthermore, its compatibility with catalytic processes and microwave-assisted reactions positions it as a forward-thinking solution for scalable production.

As the demand for high-performance chemicals continues to rise, CAS No. 379254-61-2 stands out due to its balanced properties of reactivity and stability. Its potential applications span across pharmaceutical intermediates, agrochemical formulations, and even advanced material science. For instance, its sulfonamide core is being investigated for its role in developing enzyme inhibitors and receptor modulators, which are pivotal in treating complex diseases.

In conclusion, 3-(hydrazinecarbonyl)-N-3-(trifluoromethyl)phenylbenzene-1-sulfonamide represents a fascinating area of research with broad implications. Its structural features and functional groups make it a versatile building block for innovation in multiple scientific disciplines. As researchers continue to explore its capabilities, this compound is likely to play a key role in shaping the future of specialty chemicals and life sciences.

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