Cas no 3773-07-7 (Glutathionesulfonic acid)

Glutathionesulfonic acid is a sulfonated derivative of glutathione, a tripeptide composed of glutamate, cysteine, and glycine. This modified compound exhibits enhanced solubility and stability compared to its parent molecule, making it particularly useful in biochemical and pharmaceutical research. Its sulfonic acid group introduces improved reactivity, facilitating applications in redox studies, enzyme inhibition, and as a precursor for advanced thiol-based conjugates. The compound retains the antioxidant properties of glutathione while offering greater versatility in aqueous systems. Researchers value glutathionesulfonic acid for its precise reactivity profile and utility in probing thiol-disulfide exchange mechanisms, making it a valuable tool in oxidative stress and cellular signaling studies.
Glutathionesulfonic acid structure
Glutathionesulfonic acid structure
Product Name:Glutathionesulfonic acid
CAS No:3773-07-7
MF:C10H17N3O9S
MW:355.3216817379
MDL:MFCD00057929
CID:296442
PubChem ID:24895366
Update Time:2025-10-29

Glutathionesulfonic acid Chemical and Physical Properties

Names and Identifiers

    • Glycine, L-g-glutamyl-3-sulfo-L-alanyl-
    • Glutathionesulfonic acid
    • N-(N-L-gamma-Glutamyl-3-sulfo-L-alanyl)glycine
    • MDL: MFCD00057929
    • Inchi: 1S/C10H17N3O9S/c11-5(10(18)19)1-2-7(14)13-6(4-23(20,21)22)9(17)12-3-8(15)16/h5-6H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)(H,20,21,22)/t5-,6-/m0/s1
    • InChI Key: QGWRMTHFAZVWAM-WDSKDSINSA-N
    • SMILES: S(C[C@@H](C(NCC(=O)O)=O)NC(CC[C@@H](C(=O)O)N)=O)(=O)(=O)O

Computed Properties

  • Exact Mass: 355.06861
  • Hydrogen Bond Donor Count: 6
  • Hydrogen Bond Acceptor Count: 12
  • Heavy Atom Count: 23
  • Rotatable Bond Count: 12

Experimental Properties

  • Density: 1.632±0.06 g/cm3 (20 oC 760 Torr),
  • Melting Point: 190 oC
  • Solubility: Soluble (998 g/l) (25 o C),
  • PSA: 213.19

Glutathionesulfonic acid Security Information

  • WGK Germany:3

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Glutathionesulfonic acid Suppliers

Amadis Chemical Company Limited
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(CAS:3773-07-7)Glutathionesulfonic acid
Order Number:A1025609
Stock Status:in Stock
Quantity:1g/250mg/100mg
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 15:32
Price ($):614.0/248.0/166.0

Additional information on Glutathionesulfonic acid

Introduction to Glutathionesulfonic acid (CAS No. 3773-07-7)

Glutathionesulfonic acid, with the chemical formula C5H9NO6S, is a compound that has garnered significant attention in the field of pharmaceutical and biochemical research due to its unique structural and functional properties. This compound, identified by its CAS number 3773-07-7, is a derivative of glutathione, a well-known tripeptide with immense biological significance. The introduction of a sulfonic acid group in Glutathionesulfonic acid imparts distinct chemical characteristics that make it a valuable intermediate in synthetic chemistry and a potential candidate for various therapeutic applications.

The molecular structure of Glutathionesulfonic acid features a glutathione backbone, which consists of glutamic acid, cysteine, and glycine residues. The addition of a sulfonic acid group at the terminal carboxyl group enhances the solubility and reactivity of the molecule, making it particularly useful in aqueous-based systems. This property is particularly advantageous in pharmaceutical formulations where solubility is a critical factor for drug delivery and bioavailability.

In recent years, Glutathionesulfonic acid has been explored for its potential role in modulating oxidative stress and inflammation. Glutathione itself is renowned as a major intracellular antioxidant, playing a pivotal role in protecting cells from oxidative damage caused by reactive oxygen species (ROS). The sulfonic acid derivative appears to retain these antioxidant properties while also offering additional functionalities due to the presence of the sulfonic acid moiety.

One of the most compelling areas of research involving Glutathionesulfonic acid is its application in drug development. The compound's ability to act as a precursor or intermediate in synthesizing more complex molecules has made it valuable in the production of novel therapeutic agents. For instance, researchers have investigated its use in generating derivatives that exhibit enhanced bioavailability or targeted delivery mechanisms. These advancements are particularly relevant in the context of oncology, where efficient drug delivery systems can significantly improve treatment outcomes.

Recent studies have also highlighted the potential of Glutathionesulfonic acid in managing neurological disorders. Oxidative stress and inflammation are key pathological features in conditions such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By leveraging the antioxidant and anti-inflammatory properties of Glutathionesulfonic acid, researchers aim to develop therapeutic strategies that can mitigate these pathological processes. Preliminary findings suggest that this compound may help protect neuronal cells from damage and promote neuroprotection.

The pharmacokinetic profile of Glutathionesulfonic acid is another area of active investigation. Due to its sulfonic acid group, the compound exhibits good water solubility, which facilitates its absorption and distribution throughout the body. This characteristic makes it an attractive candidate for intravenous or oral administration. Additionally, the compound's stability under various physiological conditions enhances its suitability for clinical applications.

In conclusion, Glutathionesulfonic acid (CAS No. 3773-07-7) represents a promising compound with diverse applications in pharmaceutical and biochemical research. Its unique structural features, combined with its biological activities, position it as a valuable tool for developing novel therapeutic agents. As research continues to uncover new insights into its mechanisms of action and potential benefits, Glutathionesulfonic acid is poised to play an increasingly significant role in addressing various health challenges.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:3773-07-7)Glutathionesulfonic acid
A1025609
Purity:99%/99%/99%
Quantity:1g/250mg/100mg
Price ($):614.0/248.0/166.0
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