• 1. Fate of single walled carbon nanotubes in wetland ecosystems?
  Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583
• 2. Establishing new scaling relations on two-dimensional MXenes for CO2 electroreduction?
  Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
• 3. Fc microparticles can modulate the physical extent and magnitude of complement activity?
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Nitrobenzenes

N-(2-nitrophenyl)methylhydroxylamine (CAS No. 37558-77-3): A Comprehensive Overview of Its Properties and Applications

N-(2-nitrophenyl)methylhydroxylamine (CAS No. 37558-77-3) is a specialized organic compound that has garnered significant attention in recent years due to its unique chemical structure and versatile applications. This compound, often referred to in scientific literature as 2-Nitro-N-methylhydroxylamine, belongs to the class of nitrophenyl derivatives and exhibits properties that make it valuable in various research and industrial fields. Its molecular formula, C₇H₈N₂O₃, highlights the presence of both nitro and hydroxylamine functional groups, which contribute to its reactivity and utility.

One of the most frequently searched questions about N-(2-nitrophenyl)methylhydroxylamine revolves around its synthesis and purification methods. Researchers often seek optimized protocols for its preparation, which typically involves the reaction of 2-nitrophenyl derivatives with methylhydroxylamine under controlled conditions. The compound's stability and solubility in organic solvents like ethanol, acetone, and dimethyl sulfoxide (DMSO) are also common topics of interest, as these properties are critical for its handling and application in laboratory settings.

In the context of current scientific trends, N-(2-nitrophenyl)methylhydroxylamine has been explored for its potential role in green chemistry and sustainable synthesis. With the growing emphasis on environmentally friendly processes, this compound's ability to participate in catalytic reactions and its biodegradability profile have made it a subject of study. Additionally, its applications in pharmaceutical intermediates and agrochemical research align with the increasing demand for novel compounds in drug discovery and crop protection.

The compound's spectroscopic characteristics, such as its NMR and IR spectra, are often discussed in academic forums and research papers. These analytical data are essential for identifying and characterizing N-(2-nitrophenyl)methylhydroxylamine in complex mixtures. Furthermore, its mass spectrometry profile provides insights into its fragmentation patterns, which are valuable for quality control and purity assessment in industrial applications.

Another area of interest is the compound's potential role in material science. Recent studies have investigated its use as a building block for functional polymers and coordination complexes. The nitro and hydroxylamine groups in its structure allow for diverse chemical modifications, enabling the design of materials with tailored properties for specific applications, such as sensors or catalysts.

Safety and handling guidelines for N-(2-nitrophenyl)methylhydroxylamine are also a common query among laboratory professionals. While the compound is not classified as hazardous under standard regulations, proper storage conditions—such as protection from light and moisture—are recommended to maintain its stability. Material Safety Data Sheets (MSDS) provide detailed information on its handling, including recommended personal protective equipment (PPE) and first-aid measures.

In summary, N-(2-nitrophenyl)methylhydroxylamine (CAS No. 37558-77-3) is a compound of significant scientific and industrial relevance. Its unique chemical properties, coupled with its applications in green chemistry, pharmaceuticals, and material science, make it a subject of ongoing research. As the scientific community continues to explore its potential, this compound is likely to remain a topic of interest in both academic and industrial circles.

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