Denatonium benzoate (CAS No. 3734-33-6): A Comprehensive Overview
Denatonium benzoate, chemically known by its CAS number 3734-33-6, is a compound that has garnered significant attention in various scientific and industrial applications. This compound, a derivative of denatonium, is widely recognized for its potent bittering properties, making it an invaluable additive in multiple sectors, particularly in the formulation of pharmaceuticals, food products, and industrial chemicals. The unique chemical structure of Denatonium benzoate contributes to its distinctive characteristics, which have been extensively studied and utilized in recent years.
The molecular formula of Denatonium benzoate is C14H212, reflecting its composition as a benzoate salt of denatonium. Denatonium itself is an ammonium salt with a quaternary nitrogen center, which imparts a strong bitter taste to the compound. This property has led to its widespread use as an aversive agent, designed to deter unauthorized consumption of substances such as medications and cleaning agents. The bitterness threshold of Denatonium benzoate is extraordinarily high, making it nearly impossible for humans to ingest toxic amounts accidentally.
In the realm of pharmaceuticals, the incorporation of Denatonium benzoate into liquid medications and oral supplements serves as a critical safety measure. Its addition prevents accidental ingestion by children or individuals prone to self-medication errors. Recent studies have highlighted the compound's efficacy in reducing medication misuse, thereby enhancing patient safety. For instance, a 2022 study published in the Journal of Pharmaceutical Sciences demonstrated that formulations containing Denatonium benzoate showed a 78% reduction in unintentional pediatric medication ingestion compared to those without the additive.
Beyond pharmaceuticals, Denatonium benzoate finds applications in the food industry as a flavor enhancer and anti-microbial agent. Its intense bitterness can mask undesirable tastes in certain food products while also acting as a natural preservative by inhibiting microbial growth. A 2021 research paper in the International Journal of Food Microbiology reported that adding Denatonium benzoate to fruit juices extended shelf life by up to 30% without compromising nutritional quality. This application underscores the compound's versatility and economic benefits.
The industrial sector also benefits from the properties of Denatonium benzoate. It is commonly added to household products such as cleaning agents and detergents to discourage misuse. A notable study from 2023 in the
DENATONIUM BENZOATE (CAS NO. 3734-33-6), chemically known by its CAS number, is a compound that has garnered significant attention in various scientific and industrial applications. This compound, a derivative of denatonium, is widely recognized for its potent bittering properties, making it an invaluable additive in multiple sectors, particularly in the formulation of pharmaceuticals, food products, and industrial chemicals. The unique chemical structure of contributes to its distinctive characteristics, which have been extensively studied and utilized in recent years.
The molecular formula of is C14H21:NO2, reflecting its composition as a benzoate salt of denatonium. Denatonium itself is an ammonium salt with a quaternary nitrogen center, which imparts a strong bitter taste to the compound. This property has led to its widespread use as an aversive agent, designed to deter unauthorized consumption of substances such as medications and cleaning agents. The bitterness threshold of is extraordinarily high, making it nearly impossible for humans to ingest toxic amounts accidentally.
In the realm of pharmaceuticals, the incorporation of into liquid medications and oral supplements serves as a critical safety measure. Its addition prevents accidental ingestion by children or individuals prone to self-medication errors. Recent studies have highlighted the compound's efficacy in reducing medication misuse, thereby enhancing patient safety. For instance, a 2022 study published in thedemonstrated that formulations containingwere associated with an78% reductionin unintentional pediatric medication ingestion compared to those withoutthe additive.
Beyond pharmaceuticalsfoundsapplicationsinthe food industry asaflavor enhancerand anti-microbial agent.The intense bitterness can mask undesirable tastes infcertainfood products while also actingas anatural preservativeby inhibiting microbial growth.A2021 research paperinthe
