Cas no 37308-75-1 (Flavokawain C)
Flavokawain C is a naturally occurring chalcone derivative found in kava (Piper methysticum). It exhibits notable biological activity, including potential anti-cancer, anti-inflammatory, and anti-oxidative properties. Research suggests it may induce apoptosis in certain cancer cell lines by modulating signaling pathways such as NF-κB and STAT3. Its molecular structure (C18H16O4) allows for interaction with cellular targets, making it a subject of interest in pharmacological studies. Flavokawain C is also investigated for its role in inhibiting tumor proliferation and metastasis. As a research compound, it is valued for its purity and stability, suitable for in vitro and in vivo studies. Handling requires standard laboratory precautions.
Flavokawain C structure
Product Name:Flavokawain C
CAS No:37308-75-1
MF:C17H16O5
MW:300.305945396423
MDL:MFCD00016489
CID:1482568
PubChem ID:6293081
Update Time:2025-06-06
Flavokawain C Chemical and Physical Properties
Names and Identifiers
-
- (E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
- SureCN144230
- Flavokavain C
- flavokawin
- AC1O3VJI
- Flavokawain C
- 4',6'-dimethoxy-2',4-dihydroxychalcone
- 4',6'-di-O-methylchalconaringenin
- 1-(2-hydroxy-4,6-dimethoxy)phenyl-3-(4-hydroxy)phenyl-2-propen-1-one
- 2'-hydroxy-4,6'-dimethoxychalcone
- 2',4-dihydroxy-4',6'-dimethoxychalcone
- Flavokawin C
- AQ-358
- 2',4-Dihydroxy-4',6'-dimethoxy-trans-chalcone
- 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
- Flavokavin C
- 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one
- UXUFMIJZNYXWDX-VMPITWQZSA-N
- LMPK12120320
- 4,2'-Dihydroxy-4',6'-dimethoxychalcone
- ST50308956
- Q5458168
- 2-Propen-1-one, 1-(2-hydroxy-4,6-dimeth
- (2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one
- 2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-, (2E)-
- 5LE8KTR6G2
- FLAVOKAWAINC
- AC-34389
- 37308-75-1
- AKOS024306997
- 56798-34-6
- CHEBI:157718
- (E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one (flavokawain C)
- CHEMBL251958
- 4-Hydroxyflavokawain B
- 4,2'-DIHYDROXY-4',6'-DIMETHYLCHALCONE
- MFCD00016489
- AQ-358/42003063
- 2,4-DIHYDROXY-4,6-DIMETHOXYCHALCONE
- SCHEMBL144230
- 2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-
- DTXSID60958437
- MS-24327
- 2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-, (E)-
- 2',4-Dihydroxy 4',6'-dimethoxy trans-chalcone
- CS-0034278
- Flavokawain C; 4-Hydroxyflavokavain B
- HY-N6582
-
- MDL： MFCD00016489
- Inchi： 1S/C17H16O5/c1-21-13-9-15(20)17(16(10-13)22-2)14(19)8-5-11-3-6-12(18)7-4-11/h3-10,18,20H,1-2H3/b8-5+
- InChI Key： UXUFMIJZNYXWDX-VMPITWQZSA-N
- SMILES： O(C)C1C=C(C=C(C=1C(/C=C/C1C=CC(=CC=1)O)=O)O)OC
Computed Properties
- Exact Mass: 300.10000
- Monoisotopic Mass: 300.09977361 g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 22
- Rotatable Bond Count: 5
- Complexity: 387
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 1
- Undefined Bond Stereocenter Count: 0
- Molecular Weight: 300.30
- XLogP3: 3.5
- Topological Polar Surface Area: 76
Experimental Properties
- Density: 1.279±0.06 g/cm3 (20 oC 760 Torr),
- Melting Point: 179-182 oC
- Solubility: Almost insoluble (0.018 g/l) (25 o C),
- PSA: 75.99000
- LogP: 3.01110
Flavokawain C Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| MedChemExpress | HY-N2445-5mg |
Flavokawain C |
37308-75-1 | 99.53% | 5mg |
￥800 | 2025-04-16 | |
| MedChemExpress | HY-N2445-10mg |
Flavokawain C |
37308-75-1 | 99.53% | 10mg |
￥1280 | 2025-04-16 | |
| MedChemExpress | HY-N2445-20mg |
Flavokawain C |
37308-75-1 | 99.79% | 20mg |
￥2050 | 2024-05-24 | |
| Chengdu Biopurify Phytochemicals Ltd | BP3147-20mg |
Flavokawain C |
37308-75-1 | 98% | 20mg |
$120 | 2023-09-20 | |
| Chengdu Biopurify Phytochemicals Ltd | BP3147-100mg |
Flavokawain C |
37308-75-1 | 98% | 100mg |
$420 | 2023-09-20 | |
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | T5753-1 mg |
Flavokawain C |
37308-75-1 | 98.00% | 1mg |
￥756.00 | 2022-04-26 | |
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | T5753-5 mg |
Flavokawain C |
37308-75-1 | 98.00% | 5mg |
￥1815.00 | 2022-04-26 | |
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | T5753-10 mg |
Flavokawain C |
37308-75-1 | 98.00% | 10mg |
￥3055.00 | 2022-04-26 | |
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | T5753-25 mg |
Flavokawain C |
37308-75-1 | 98.00% | 25mg |
￥5687.00 | 2022-04-26 | |
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | T5753-1 mL * 10 mM (in DMSO) |
Flavokawain C |
37308-75-1 | 98.00% | 1 mL * 10 mM (in DMSO) |
￥1815.00 | 2022-04-26 |
Flavokawain C Related Literature
-
Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
-
Zhixia Liu,Tingjian Chen,Floyd E. Romesberg Chem. Sci., 2017,8, 8179-8182
-
Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
-
J. Xu,T. J. Carrocci,A. A. Hoskins Chem. Commun., 2016,52, 549-552
Related Categories
- Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Linear 1,3-diarylpropanoids 2'-Hydroxychalcones
- Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Linear 1,3-diarylpropanoids Chalcones and dihydrochalcones 2'-Hydroxychalcones
- Chalcones
37308-75-1 (Flavokawain C) Related Products
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- 3420-72-2(Flavokawain A)
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- 65349-31-7(2-Propen-1-one,1-(2,4-dihydroxy-6-methoxy-3,5-dimethylphenyl)-3-phenyl-)
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