Cas no 372963-48-9 ((4-Methylpyridin-2-yl)boronic acid)

(4-Methylpyridin-2-yl)boronic acid is a boronic acid derivative featuring a pyridine ring substituted with a methyl group at the 4-position. This compound serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling the synthesis of biaryl and heteroaryl structures with high selectivity. Its stability under mild conditions and compatibility with various functional groups make it a valuable reagent in pharmaceutical and materials science research. The presence of the methyl group enhances steric and electronic properties, facilitating controlled reactivity in complex transformations. Typical applications include the preparation of ligands, catalysts, and bioactive molecules. Proper handling under inert conditions is recommended to preserve its reactivity.
(4-Methylpyridin-2-yl)boronic acid structure
372963-48-9 structure
Product Name:(4-Methylpyridin-2-yl)boronic acid
CAS No:372963-48-9
MF:C6H8BNO2
MW:136.944221496582
MDL:MFCD03093330
CID:303995
PubChem ID:2762744
Update Time:2025-06-09

(4-Methylpyridin-2-yl)boronic acid Chemical and Physical Properties

Names and Identifiers

    • (4-Methylpyridin-2-yl)boronic acid
    • 4-Methylpyridine-2-boronic acid
    • Boronic acid,B-(4-methyl-2-pyridinyl)-
    • 4-Methylpyridin-2-ylboronic acid
    • 4-methylpyridine-2-boronic acid, AldrichCPR
    • AB13221
    • FT-0600766
    • J-515813
    • 372963-48-9
    • BS-25122
    • A823588
    • BORONIC ACID, (4-METHYL-2-PYRIDINYL)-
    • 4-Picoline-2-boronicacid
    • EN300-155111
    • CS-0175834
    • AKOS006220917
    • SCHEMBL1843835
    • (4-methyl-2-pyridinyl)boronic acid
    • MFCD03093330
    • CGRJYCBMVWNLPD-UHFFFAOYSA-N
    • DTXSID40376413
    • 4-Methylpyridin-2-YL boronic acid
    • DB-026256
    • SY300233
    • MDL: MFCD03093330
    • Inchi: 1S/C6H8BNO2/c1-5-2-3-8-6(4-5)7(9)10/h2-4,9-10H,1H3
    • InChI Key: CGRJYCBMVWNLPD-UHFFFAOYSA-N
    • SMILES: OB(C1C=C(C)C=CN=1)O

Computed Properties

  • Exact Mass: 137.06500
  • Monoisotopic Mass: 137.065
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 110
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 53.4A^2

Experimental Properties

  • Density: 1.18
  • Boiling Point: 335.5°Cat760mmHg
  • Flash Point: 156.7°C
  • Refractive Index: 1.527
  • PSA: 53.35000
  • LogP: -0.93020

(4-Methylpyridin-2-yl)boronic acid Security Information

  • Hazard Category Code: 37/38-41
  • Safety Instruction: 26-39
  • Hazardous Material Identification: Xi

(4-Methylpyridin-2-yl)boronic acid Pricemore >>

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(4-Methylpyridin-2-yl)boronic acid Production Method

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