Cas no 37153-52-9 (Bromoclenbuterol)
Bromoclenbuterol Chemical and Physical Properties
Names and Identifiers
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- Benzenemethanol,4-amino-3-bromo-5-chloro-a-[[(1,1-dimethylethyl)amino]methyl]-
- 1-(4-amino-3-bromo-5-chlorophenyl)-2-(tert-butylamino)ethanol
- BROMOCLENBUTEROL
- Clenbuterol Impurity F
- Benzenemethanol, 4-amino-3-bromo-5-chloro-alpha-[[(1,1-dimethylethyl)amino]methyl]-
- CLENBUTEROL HYDROCHLORIDE IMPURITY F [EP IMPURITY]
- (1RS)-1-(4-amino-3-bromo-5-chlorophenyl)-2-[(1,1-dimethylethyl)amino]ethanol
- NS00040820
- 4-Amino-3-bromo-5-chloro-alpha-[[(1,1-dimethylethyl)amino]methyl]benzenemethanol
- SCHEMBL10614327
- DTXSID80376770
- 4KJ88YP4R5
- Bromchlorbuterol
- FT-0730841
- 37153-52-9
- Bromoclenbuterol
-
- Inchi: 1S/C12H18BrClN2O/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7/h4-5,10,16-17H,6,15H2,1-3H3
- InChI Key: RBROAKIHDILEQG-UHFFFAOYSA-N
- SMILES: BrC1=C(C(=CC(=C1)C(CNC(C)(C)C)O)Cl)N
Computed Properties
- Exact Mass: 320.02900
- Monoisotopic Mass: 320.029
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 17
- Rotatable Bond Count: 4
- Complexity: 247
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 1
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 58.3A^2
- XLogP3: 2.3
Experimental Properties
- Density: 1.424
- Boiling Point: 430.3°Cat760mmHg
- Flash Point: 214°C
- Refractive Index: 1.59
- PSA: 58.28000
- LogP: 4.07830
Bromoclenbuterol Security Information
- Signal Word:warning
- Hazard Statement: H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement: P264+P280+P305+P351+P338+P337+P313
- Safety Instruction: H303+H313+H333
- Storage Condition:Store at recommended temperature
Bromoclenbuterol Customs Data
- HS CODE:2922199090
- Customs Data:
China Customs Code:
2922199090Overview:
2922199090. Other amino alcohols and their ethers,Esters and their salts(Except those containing more than one oxygen-containing group). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%
Declaration elements:
Product Name, component content, use to, The color of ethanolamine and its salt should be reported, The package of ethanolamine and its salt shall be declared
Summary:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Bromoclenbuterol Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | B606535-2.5mg |
Bromoclenbuterol |
37153-52-9 | 2.5mg |
$ 190.00 | 2023-04-18 | ||
| TRC | B606535-10mg |
Bromoclenbuterol |
37153-52-9 | 10mg |
$ 718.00 | 2023-04-18 | ||
| TRC | B606535-25mg |
Bromoclenbuterol |
37153-52-9 | 25mg |
$ 1499.00 | 2023-04-18 | ||
| TRC | B606535-100mg |
Bromoclenbuterol |
37153-52-9 | 100mg |
$ 4500.00 | 2023-09-08 |
Bromoclenbuterol Suppliers
Bromoclenbuterol Related Literature
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Martin R. Ward,Gary W. Copeland,Andrew J. Alexander Chem. Commun., 2010,46, 7634-7636
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Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
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Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
-
Hui Liu,Deyong Su,Guolin Cheng,Jimin Xu,Xinyan Wang,Yuefei Hu Org. Biomol. Chem., 2010,8, 1899-1904
Additional information on Bromoclenbuterol
Bromoclenbuterol (CAS No. 37153-52-9): A Comprehensive Overview of Its Chemical Profile and Emerging Applications
Bromoclenbuterol, identified by the Chemical Abstracts Service Number (CAS No.) 37153-52-9, is a compound that has garnered significant attention in the field of pharmaceutical research and biochemical studies. As a derivative of the well-known β?-adrenergic receptor agonist clenbuterol, Bromoclenbuterol exhibits distinct pharmacological properties that make it a subject of interest for both therapeutic and experimental purposes. This article provides an in-depth exploration of the chemical characteristics, pharmacological effects, and the latest research findings associated with Bromoclenbuterol.
The molecular structure of Bromoclenbuterol (CAS No. 37153-52-9) incorporates a bromine substituent at the clencainyl group, which is believed to modulate its receptor binding affinity and metabolic stability. This structural modification has been investigated for its potential to enhance selectivity and reduce side effects compared to its parent compound. The compound’s chemical formula is C12H18BrNO3, reflecting its molecular weight and composition.
In recent years, Bromoclenbuterol has been studied for its potential applications in treating respiratory disorders. Unlike clenbuterol, which is primarily used as a bronchodilator in veterinary medicine, Bromoclenbuterol has shown promise in preclinical trials for its ability to stimulate β?-adrenergic receptors with higher specificity. This property could lead to fewer cardiovascular side effects, making it a more suitable candidate for human therapeutic use. Research published in peer-reviewed journals indicates that Bromoclenbuterol may offer improved efficacy in conditions such as asthma and chronic obstructive pulmonary disease (COPD).
The pharmacokinetic profile of Bromoclenbuterol (CAS No. 37153-52-9) has also been a focus of scientific investigation. Studies have demonstrated that the compound exhibits a relatively short half-life, which could influence its dosing regimen and potential for accumulation in biological systems. Additionally, the presence of the bromine atom appears to enhance its lipophilicity, potentially allowing for better penetration across cellular membranes. These characteristics are critical for determining its bioavailability and therapeutic window.
Emerging research suggests that Bromoclenbuterol may have applications beyond respiratory medicine. Preliminary findings indicate that it could possess anabolic properties, making it attractive for studying muscle growth and wasting conditions. The compound’s ability to activate β?-adrenergic receptors might also contribute to its potential use in metabolic disorders, such as obesity and type 2 diabetes. However, further clinical trials are necessary to validate these hypotheses and establish safe dosages.
The synthesis of Bromoclenbuterol (CAS No. 37153-52-9) involves multi-step organic reactions that require precise control over reaction conditions to ensure high yield and purity. The bromination step is particularly critical, as it determines the position and reactivity of the bromine substituent on the molecular framework. Advances in synthetic methodologies have enabled more efficient production processes, which could facilitate broader research applications.
Ethical considerations are paramount when investigating compounds like Bromoclenbuterol. While preclinical studies have provided promising insights into its potential benefits, human trials must be conducted under stringent regulatory frameworks to ensure patient safety and data integrity. Collaborative efforts between academic institutions and pharmaceutical companies are essential for translating laboratory findings into viable therapeutic options.
The future of Bromoclenbuterol research lies in exploring its mechanisms of action and identifying novel therapeutic targets. By leveraging cutting-edge techniques such as computational modeling and high-throughput screening, scientists can uncover new applications for this compound. Additionally, investigating its interactions with other biological pathways may reveal synergistic effects that could enhance its clinical utility.
In conclusion, Bromoclenbuterol, with its CAS Number 37153-52-9, represents a fascinating compound with diverse potential applications in medicine and biotechnology. Its unique chemical properties and pharmacological effects make it a valuable subject for ongoing research. As scientific understanding continues to evolve, the possibilities for utilizing this compound in addressing various health challenges appear promising.
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