Cas no 368-87-6 (4-hydroxybenzene-1-sulfonyl fluoride)
4-Hydroxybenzene-1-sulfonyl fluoride is a sulfonyl fluoride derivative of phenol, primarily utilized as a reactive intermediate in organic synthesis and chemical biology. Its key advantage lies in its selective reactivity with serine hydrolases, making it a valuable probe for activity-based protein profiling (ABPP) and covalent inhibitor development. The compound’s sulfonyl fluoride group exhibits high electrophilicity, enabling efficient covalent modification of target proteins under mild conditions. Additionally, the phenolic hydroxyl group provides a handle for further functionalization or conjugation. This compound is particularly useful in medicinal chemistry and proteomics research due to its stability in aqueous environments and compatibility with bioorthogonal reactions.
368-87-6 structure
Product Name:4-hydroxybenzene-1-sulfonyl fluoride
CAS No:368-87-6
MF:C6H5FO3S
MW:176.165504217148
MDL:MFCD23110943
CID:320242
PubChem ID:308444
Update Time:2025-10-29
4-hydroxybenzene-1-sulfonyl fluoride Chemical and Physical Properties
Names and Identifiers
-
- Benzenesulfonylfluoride, 4-hydroxy-
- 4-hydroxybenzenesulfonyl fluoride
- 4-fluorosulfonyl phenol
- 4-hydroxy-benzenesulfonyl fluoride
- 4-Hydroxy-benzolsulfonylfluorid
- AC1L7CW2
- CTK1C6069
- NSC210243
- Phenol-sulfonsaeure-(4)-fluorid
- p-Hydroxybenzolsulfonylfluorid
- DTXSID90308840
- 368-87-6
- EN300-211260
- E85133
- 4-Hydroxybenzene-1-sulfonyl fluoride
- 4-Hydroxybenzene-1-sulfonylfluoride
- Z1513807665
- AKOS037652480
- SCHEMBL6308565
- NSC-210243
- CS-0159343
- ES-2183
- DS-001404
- 4-hydroxybenzene-1-sulfonyl fluoride
-
- MDL： MFCD23110943
- Inchi： 1S/C6H5FO3S/c7-11(9,10)6-3-1-5(8)2-4-6/h1-4,8H
- InChI Key： FYIHSKNNTBQVMV-UHFFFAOYSA-N
- SMILES： S(C1C=CC(=CC=1)O)(=O)(=O)F
Computed Properties
- Exact Mass: 175.99435
- Monoisotopic Mass: 175.99434335g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 11
- Rotatable Bond Count: 1
- Complexity: 211
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 1.3
- Topological Polar Surface Area: 62.8?2
Experimental Properties
- PSA: 54.37
4-hydroxybenzene-1-sulfonyl fluoride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | H829028-10mg |
4-hydroxybenzene-1-sulfonyl fluoride |
368-87-6 | 10mg |
$ 70.00 | 2022-06-04 | ||
| TRC | H829028-50mg |
4-hydroxybenzene-1-sulfonyl fluoride |
368-87-6 | 50mg |
$ 250.00 | 2022-06-04 | ||
| TRC | H829028-100mg |
4-hydroxybenzene-1-sulfonyl fluoride |
368-87-6 | 100mg |
$ 365.00 | 2022-06-04 | ||
| eNovation Chemicals LLC | Y1229821-1g |
4-Hydroxybenzene-1-sulfonyl fluoride |
368-87-6 | 95% | 1g |
$1000 | 2024-06-03 | |
| Enamine | EN300-211260-0.05g |
4-hydroxybenzene-1-sulfonyl fluoride |
368-87-6 | 95% | 0.05g |
$293.0 | 2023-09-16 | |
| Enamine | EN300-211260-0.1g |
4-hydroxybenzene-1-sulfonyl fluoride |
368-87-6 | 95% | 0.1g |
$437.0 | 2023-09-16 | |
| Enamine | EN300-211260-0.25g |
4-hydroxybenzene-1-sulfonyl fluoride |
368-87-6 | 95% | 0.25g |
$623.0 | 2023-09-16 | |
| Enamine | EN300-211260-0.5g |
4-hydroxybenzene-1-sulfonyl fluoride |
368-87-6 | 95% | 0.5g |
$980.0 | 2023-09-16 | |
| Enamine | EN300-211260-1.0g |
4-hydroxybenzene-1-sulfonyl fluoride |
368-87-6 | 95% | 1g |
$1256.0 | 2023-05-26 | |
| Enamine | EN300-211260-2.5g |
4-hydroxybenzene-1-sulfonyl fluoride |
368-87-6 | 95% | 2.5g |
$2464.0 | 2023-09-16 |
4-hydroxybenzene-1-sulfonyl fluoride Suppliers
Amadis Chemical Company Limited
Gold Member
Audited Supplier
(CAS:368-87-6)4-hydroxybenzene-1-sulfonyl fluoride
Order Number:A1024990
Stock Status:in Stock
Quantity:1g
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 15:31
Price ($):183.0
Email:[email protected]
4-hydroxybenzene-1-sulfonyl fluoride Related Literature
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Joo Chuan Yeo,Kenry Lab Chip, 2016,16, 4082-4090
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Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583
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A. B. F. da Silva,K. Capelle Phys. Chem. Chem. Phys., 2009,11, 4564-4569
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Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
-
Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
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Recommended suppliers
Amadis Chemical Company Limited
(CAS:368-87-6)4-hydroxybenzene-1-sulfonyl fluoride
Purity:99%
Quantity:1g
Price ($):183.0