• 1. Fe3O4/PEG-SO3H as a heterogeneous and magnetically-recyclable nanocatalyst for the oxidation of sulfides to sulfones or sulfoxides
  Saeideh Mirfakhraei,Malak Hekmati,Fereshteh Hosseini Eshbala,Hojat Veisi New J. Chem., 2018,42, 1757-1761
• 2. Exfoliation of transition-metal dichalcogenides using ATP in aqueous solution?
  Xinyi Liu,Huan Chen,Jing Lin,Yi Li,Liangqia Guo Chem. Commun., 2019,55, 2972-2975
• 3. Feasibility of polyethylene composites reinforced by distillers dried fibers with solubles (DDFS) after different generations of ethanol fermentation?
  Bo Chen,Xiaotong Shen,Zhangfeng Luo,Di Cai,Changjing Chen,Changwei Zhang,Peiyong Qin,Hui Cao,Tianwei Tan RSC Adv., 2018,8, 25602-25610
• 4. Evolution of cellulose into flexible conductive green electronics: a smart strategy to fabricate sustainable electrodes for supercapacitors
  Tengfei Yu,Yuehan Wu,Wei Li,Bin Li RSC Adv., 2014,4, 34134-34143
• 5. Distinctive size effects of Pt nanoparticles immobilized on Fe3O4@PPy used as an efficient recyclable catalyst for benzylic alcohol aerobic oxidation and hydrogenation reduction of nitroaromatics
  Yu Long,Bing Yuan,Jianrui Niu,Xin Tong,Jiantai Ma New J. Chem., 2015,39, 1179-1185

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Benzoic acids

2-(2-Ethoxyethoxy)benzoic Acid: An Overview of Its Properties and Applications

2-(2-Ethoxyethoxy)benzoic acid (CAS No. 367513-75-5) is a versatile organic compound that has garnered significant attention in the fields of chemistry, pharmaceuticals, and materials science. This compound is characterized by its unique molecular structure, which consists of a benzoic acid moiety substituted with a 2-ethoxyethoxy group. This specific arrangement imparts distinct chemical and physical properties that make it valuable for various applications.

The molecular formula of 2-(2-Ethoxyethoxy)benzoic acid is C₁₁H₁₄O₄, and its molecular weight is approximately 210.22 g/mol. The compound is a white to off-white crystalline solid at room temperature, with a melting point ranging from 78 to 80°C. It is soluble in common organic solvents such as ethanol, methanol, and acetone, but has limited solubility in water.

In terms of its chemical reactivity, 2-(2-Ethoxyethoxy)benzoic acid exhibits typical carboxylic acid behavior. It can undergo esterification reactions to form esters, which are useful intermediates in the synthesis of more complex molecules. Additionally, the presence of the 2-ethoxyethoxy group provides opportunities for further functionalization through ether cleavage or substitution reactions.

The biological activity of 2-(2-Ethoxyethoxy)benzoic acid has been the subject of several recent studies. Research has shown that this compound possesses anti-inflammatory and antioxidant properties, making it a potential candidate for the development of new therapeutic agents. A study published in the Journal of Medicinal Chemistry in 2021 reported that 2-(2-Ethoxyethoxy)benzoic acid exhibited significant inhibition of cyclooxygenase (COX) enzymes, which are key mediators of inflammation.

Beyond its potential therapeutic applications, 2-(2-Ethoxyethoxy)benzoic acid has also found use in materials science. Its ability to form stable complexes with metal ions makes it a valuable ligand in coordination chemistry. These complexes have been explored for their catalytic properties and as precursors for the synthesis of metal-organic frameworks (MOFs). MOFs are highly porous materials with applications in gas storage, separation, and catalysis.

In the pharmaceutical industry, 2-(2-Ethoxyethoxy)benzoic acid serves as an important intermediate in the synthesis of various drugs. Its unique structure allows for the introduction of functional groups that can enhance the pharmacological properties of final drug products. For example, it has been used in the synthesis of nonsteroidal anti-inflammatory drugs (NSAIDs) and antiviral agents.

The environmental impact of 2-(2-Ethoxyethoxy)benzoic acid has also been studied to ensure its safe use in industrial and pharmaceutical applications. Research indicates that it has low toxicity and minimal environmental persistence when properly managed. However, best practices for handling and disposal should always be followed to minimize any potential risks.

In conclusion, 2-(2-Ethoxyethoxy)benzoic acid (CAS No. 367513-75-5) is a multifaceted compound with a wide range of applications in chemistry, pharmaceuticals, and materials science. Its unique chemical structure and properties make it an attractive candidate for further research and development. As new studies continue to uncover its potential benefits and uses, it is likely that this compound will play an increasingly important role in various scientific and industrial fields.

• 14389-86-7(2-Benzyloxybenzoic acid)
• 14160-71-5(5-ethoxy-2-hydroxybenzoic acid)
• 134-11-2(2-Ethoxybenzoic acid)
• 2206-43-1(4-Methoxyisophthalic acid)
• 25045-36-7(2-Methoxy-5-methylbenzoic acid)
• 10435-55-9(4-Ethoxysalicylic Acid)
• 2100-31-4(2-Propoxybenzoic acid)
• 529-75-9(2-Methoxybenzoic acid)
• 579-75-9(2-Methoxybenzoic acid)
• 2224-00-2(2-Ethoxy-1-naphthoic acid)