Cas no 365413-16-7 (Ethyl 6-(Methylamino)pyridazine-3-carboxylate)

Ethyl 6-(Methylamino)pyridazine-3-carboxylate is a versatile pyridazine derivative widely utilized in pharmaceutical and agrochemical research. This compound features a methylamino substituent at the 6-position and an ethyl ester group at the 3-position, offering a reactive scaffold for further functionalization. Its pyridazine core contributes to strong hydrogen bonding and π-stacking interactions, enhancing binding affinity in target applications. The ethyl ester moiety provides synthetic flexibility, enabling easy hydrolysis or transesterification for downstream modifications. With high purity and stability, it serves as a key intermediate in the synthesis of bioactive molecules, particularly in developing kinase inhibitors and antimicrobial agents. Its well-defined structure and reactivity make it valuable for structure-activity relationship (SAR) studies in medicinal chemistry.
Ethyl 6-(Methylamino)pyridazine-3-carboxylate structure
365413-16-7 structure
Product Name:Ethyl 6-(Methylamino)pyridazine-3-carboxylate
CAS No:365413-16-7
MF:C8H11N3O2
MW:181.191841363907
MDL:MFCD28014556
CID:2083837
PubChem ID:22271465
Update Time:2025-07-02

Ethyl 6-(Methylamino)pyridazine-3-carboxylate Chemical and Physical Properties

Names and Identifiers

    • Ethyl 6-(Methylamino)pyridazine-3-carboxylate
    • DB-230441
    • EN300-6509933
    • AKOS027256944
    • AC6007
    • MBRXPNIOOHRVMY-UHFFFAOYSA-N
    • DTXSID301254463
    • Ethyl 6-(methylamino)-3-pyridazinecarboxylate
    • ethyl6-(methylamino)pyridazine-3-carboxylate
    • BS-50730
    • SY028791
    • Ethyl 3-methylaminopyridazine-6-carboxylate
    • SCHEMBL4041873
    • 365413-16-7
    • CS-0151653
    • MFCD28014556
    • MDL: MFCD28014556
    • Inchi: 1S/C8H11N3O2/c1-3-13-8(12)6-4-5-7(9-2)11-10-6/h4-5H,3H2,1-2H3,(H,9,11)
    • InChI Key: MBRXPNIOOHRVMY-UHFFFAOYSA-N
    • SMILES: O(C(C1=CC=C(N=N1)NC)=O)CC

Computed Properties

  • Exact Mass: 181.085126602g/mol
  • Monoisotopic Mass: 181.085126602g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 3
  • Complexity: 175
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -0.5
  • Topological Polar Surface Area: 64.1?2

Experimental Properties

  • Density: 1.2±0.0 g/cm3
  • Boiling Point: 379.0±0.0 °C at 760 mmHg
  • Flash Point: 183.0±0.0 °C
  • Vapor Pressure: 0.0±0.0 mmHg at 25°C

Ethyl 6-(Methylamino)pyridazine-3-carboxylate Security Information

Ethyl 6-(Methylamino)pyridazine-3-carboxylate Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
A029185330-5g
Ethyl 6-(Methylamino)pyridazine-3-carboxylate
365413-16-7 95%
5g
$765.60 2023-09-02
Chemenu
CM324655-5g
Ethyl 6-(Methylamino)pyridazine-3-carboxylate
365413-16-7 95%
5g
$651 2021-08-18
ChemScence
CS-0151653-100mg
Ethyl 6-(Methylamino)pyridazine-3-carboxylate
365413-16-7
100mg
$54.0 2022-04-27
ChemScence
CS-0151653-250mg
Ethyl 6-(Methylamino)pyridazine-3-carboxylate
365413-16-7
250mg
$80.0 2022-04-27
ChemScence
CS-0151653-1g
Ethyl 6-(Methylamino)pyridazine-3-carboxylate
365413-16-7
1g
$199.0 2022-04-27
ChemScence
CS-0151653-5g
Ethyl 6-(Methylamino)pyridazine-3-carboxylate
365413-16-7
5g
$700.0 2022-04-27
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
X12325-1g
Ethyl 6-(Methylamino)pyridazine-3-carboxylate
365413-16-7 95%
1g
¥937.0 2024-07-18
Apollo Scientific
OR470978-1g
Ethyl 6-(Methylamino)pyridazine-3-carboxylate
365413-16-7
1g
£343.00 2023-08-31
Chemenu
CM324655-250mg
Ethyl 6-(Methylamino)pyridazine-3-carboxylate
365413-16-7 95%
250mg
$91 2023-03-07
Chemenu
CM324655-1g
Ethyl 6-(Methylamino)pyridazine-3-carboxylate
365413-16-7 95%
1g
$221 2023-03-07

Additional information on Ethyl 6-(Methylamino)pyridazine-3-carboxylate

Comprehensive Overview of Ethyl 6-(Methylamino)pyridazine-3-carboxylate (CAS No. 365413-16-7)

Ethyl 6-(Methylamino)pyridazine-3-carboxylate (CAS No. 365413-16-7) is a specialized organic compound that has garnered significant attention in pharmaceutical and agrochemical research. This pyridazine derivative is known for its unique structural properties, making it a valuable intermediate in the synthesis of bioactive molecules. Researchers and industry professionals frequently search for terms like "pyridazine carboxylate synthesis" or "ethyl 6-methylamino pyridazine applications," reflecting its growing relevance in modern chemistry.

The compound's molecular structure features a pyridazine ring substituted with a methylamino group at the 6-position and an ethyl carboxylate moiety at the 3-position. This configuration contributes to its versatility in medicinal chemistry, particularly in the development of kinase inhibitors and antimicrobial agents. Recent studies highlight its potential in addressing antibiotic resistance, a hot topic in drug discovery circles. Searches for "CAS 365413-16-7 solubility" or "pyridazine-based drug candidates" indicate strong interest in its physicochemical properties.

From a synthetic perspective, Ethyl 6-(Methylamino)pyridazine-3-carboxylate serves as a crucial building block for heterocyclic compounds. Its carboxylate ester functionality allows for further derivatization, making it popular in combinatorial chemistry approaches. Laboratory queries often include "365413-16-7 reaction conditions" or "methylamino pyridazine stability," underscoring the need for precise handling protocols. The compound's stability under various pH conditions has been particularly noted in recent pharmaceutical formulation studies.

In agrochemical applications, this pyridazine derivative shows promise as a precursor for crop protection agents. With increasing global focus on sustainable agriculture, researchers are investigating its potential in developing environmentally friendly pesticides. Search trends reveal growing interest in "pyridazine carboxylate mode of action" and "365413-16-7 agricultural uses," aligning with the industry's shift toward green chemistry solutions.

Analytical characterization of CAS 365413-16-7 typically involves advanced techniques like HPLC-MS and NMR spectroscopy. The scientific community frequently searches for "ethyl 6-methylamino pyridazine spectral data" and "365413-16-7 purity analysis," reflecting the compound's importance in quality control processes. Recent advancements in analytical chemistry have enabled more precise quantification of this compound in complex matrices.

The commercial availability of Ethyl 6-(Methylamino)pyridazine-3-carboxylate has expanded significantly, with suppliers offering various purity grades. Procurement-related searches such as "buy 365413-16-7" or "pyridazine carboxylate suppliers" demonstrate its established market presence. Current Good Manufacturing Practice (cGMP) compliant versions are increasingly demanded for pharmaceutical development applications.

Future research directions for this compound include exploration of its structure-activity relationships and potential in targeted drug delivery systems. The scientific literature shows growing citations for "365413-16-7 biological activity" and "pyridazine pharmacokinetics," indicating expanding therapeutic investigations. Its role in precision medicine approaches represents a particularly promising avenue for further study.

From an environmental standpoint, the biodegradation profile of Ethyl 6-(Methylamino)pyridazine-3-carboxylate has become a subject of regulatory interest. Queries about "365413-16-7 ecotoxicity" and "pyridazine environmental fate" reflect compliance concerns in industrial applications. Recent green chemistry initiatives have focused on developing more sustainable synthetic routes for this valuable intermediate.

In conclusion, Ethyl 6-(Methylamino)pyridazine-3-carboxylate (CAS No. 365413-16-7) represents a multifaceted compound with diverse applications across pharmaceutical, agrochemical, and material science domains. Its growing prominence in scientific literature and search engine queries underscores its importance as a versatile chemical building block in contemporary research and industrial applications.

Recommended suppliers
Inner Mongolia Xinhong Biological Technology Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Inner Mongolia Xinhong Biological Technology Co., Ltd
Zhejiang Brunova Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Zhejiang Brunova Technology Co., Ltd.
Suzhou Genelee Bio-Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Suzhou Genelee Bio-Technology Co., Ltd.
Shandong Jing Kun Chemical Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shandong Jing Kun Chemical Co.,Ltd.
Jiangsu Xinsu New Materials Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jiangsu Xinsu New Materials Co., Ltd