Cas no 36507-21-8 (3-Pyridinecarboxamide,6-(dimethylamino)-)

3-Pyridinecarboxamide,6-(dimethylamino)- is a heterocyclic organic compound featuring a pyridine core substituted with a dimethylamino group at the 6-position and a carboxamide functional group at the 3-position. This structure imparts unique electronic and steric properties, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. The dimethylamino group enhances solubility and reactivity, while the carboxamide moiety offers versatility for further derivatization. Its well-defined molecular architecture ensures consistent performance in coupling reactions and as a building block for bioactive molecules. The compound is characterized by high purity and stability, making it suitable for research and industrial applications requiring precise chemical functionality.
3-Pyridinecarboxamide,6-(dimethylamino)- structure
36507-21-8 structure
Product Name:3-Pyridinecarboxamide,6-(dimethylamino)-
CAS No:36507-21-8
MF:C8H11N3O
MW:165.192441225052
CID:316957
PubChem ID:96420
Update Time:2025-08-03

3-Pyridinecarboxamide,6-(dimethylamino)- Chemical and Physical Properties

Names and Identifiers

    • 3-Pyridinecarboxamide,6-(dimethylamino)-
    • 6-(dimethylamino)pyridine-3-carboxamide
    • 6-(dimethylamino)nicotinamide
    • 6-Dimethylaminonicotinamid
    • 6-dimethylamino-nicotinamide
    • 6-Dimethylaminonicotinamide
    • AC1L3WF2
    • AC1Q5FUT
    • CTK4H6555
    • NCIOpen2_000396
    • Nicotinamide, 6-(dimethylamino)-
    • NSC73291
    • SureCN976946
    • DTXSID30190009
    • NCI60_041600
    • NSC 73291
    • 6-(DIMETHYLAMINO)-3-PYRIDINECARBOXAMIDE
    • CHEMBL1997189
    • L7VJ50456Q
    • UNII-L7VJ50456Q
    • BDBM50455077
    • AI3-52721
    • 36507-21-8
    • SCHEMBL976946
    • NSC-73291
    • SB54877
    • 3-Pyridinecarboxamide, 6-(dimethylamino)-
    • Inchi: 1S/C8H11N3O/c1-11(2)7-4-3-6(5-10-7)8(9)12/h3-5H,1-2H3,(H2,9,12)
    • InChI Key: HLUIYGVTAGXCRZ-UHFFFAOYSA-N
    • SMILES: O=C(C1=CN=C(C=C1)N(C)C)N

Computed Properties

  • Exact Mass: 165.09033
  • Monoisotopic Mass: 165.09
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 2
  • Complexity: 170
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.5
  • Topological Polar Surface Area: 59.2?2

Experimental Properties

  • Density: 1.185
  • Boiling Point: 347.5°Cat760mmHg
  • Flash Point: 164°C
  • Refractive Index: 1.598
  • PSA: 59.22

3-Pyridinecarboxamide,6-(dimethylamino)- Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Chemenu
CM519022-1g
6-(Dimethylamino)nicotinamide
36507-21-8 97%
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$505 2022-06-11

Additional information on 3-Pyridinecarboxamide,6-(dimethylamino)-

Comprehensive Overview of 3-Pyridinecarboxamide,6-(dimethylamino)- (CAS No. 36507-21-8)

3-Pyridinecarboxamide,6-(dimethylamino)-, with the CAS number 36507-21-8, is a specialized organic compound that has garnered significant attention in pharmaceutical and chemical research. This compound, often referred to by its systematic name, belongs to the pyridine family, a class of heterocyclic compounds known for their versatility in medicinal chemistry and material science. The presence of the dimethylamino group at the 6-position and the carboxamide functionality at the 3-position makes this molecule a valuable intermediate in the synthesis of more complex structures.

In recent years, the demand for pyridine derivatives has surged due to their applications in drug discovery and agrochemical development. Researchers are particularly interested in 6-(dimethylamino)-3-pyridinecarboxamide for its potential as a building block in the creation of novel therapeutics. Its unique structural features allow for modifications that can enhance bioavailability and target specificity, making it a hotspot in structure-activity relationship (SAR) studies. The compound's CAS registry number 36507-21-8 is frequently searched in scientific databases, reflecting its growing relevance in academic and industrial settings.

The synthesis of 3-Pyridinecarboxamide,6-(dimethylamino)- typically involves multi-step organic reactions, including amidation and alkylation processes. Advanced techniques such as microwave-assisted synthesis and catalyzed cross-coupling reactions have been explored to improve yield and efficiency. These methods align with the broader trend of green chemistry, a topic of high interest among environmentally conscious researchers. Optimizing the production of this compound while minimizing waste and energy consumption is a key focus area, addressing the global push for sustainable chemical practices.

From an analytical perspective, 36507-21-8 is characterized using techniques like nuclear magnetic resonance (NMR), mass spectrometry (MS), and high-performance liquid chromatography (HPLC). These tools ensure purity and confirm structural integrity, which are critical for its application in high-stakes industries. The compound's spectral data is often shared in open-access journals, facilitating collaboration and accelerating research progress. This transparency is part of a larger movement toward open science, another trending topic in the scientific community.

Beyond its pharmaceutical potential, 3-Pyridinecarboxamide,6-(dimethylamino)- has also been investigated for its role in material science. Its ability to form stable complexes with metals and other organic molecules makes it a candidate for developing advanced materials, such as organic semiconductors and catalysts. This dual applicability underscores the compound's versatility and aligns with the increasing interdisciplinary nature of modern research. Searches for pyridine-based materials and functionalized heterocycles often lead to discussions about this compound, highlighting its cross-disciplinary importance.

In conclusion, 3-Pyridinecarboxamide,6-(dimethylamino)- (CAS 36507-21-8) is a compound of significant scientific and industrial interest. Its structural uniqueness, combined with its broad applicability, positions it as a key player in ongoing research efforts. Whether in the context of drug development, green chemistry, or advanced materials, this molecule continues to inspire innovation and collaboration across multiple fields. As the scientific community moves toward more sustainable and efficient practices, compounds like this will undoubtedly remain at the forefront of discovery.

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