• 1. Examination of ammonia–poly(pyrrole) interactions by piezoelectric and conductivity measurements
  Analyst, 1991,116, 1125-1130
• 2. Emulsion technologies for multicellular tumour spheroid radiation assays?
  Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
• 3. Emergence of microfluidic wearable technologies
  Joo Chuan Yeo,Kenry Lab Chip, 2016,16, 4082-4090
• 4. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Benzoic acids

Comprehensive Overview of 4-(4-Bromophenoxy)methylbenzoic Acid (CAS No. 364623-84-7): Properties, Applications, and Research Insights

4-(4-Bromophenoxy)methylbenzoic acid (CAS No. 364623-84-7) is a specialized organic compound gaining attention in pharmaceutical and material science research. This brominated aromatic derivative features a unique molecular structure combining a benzoic acid core with a 4-bromophenoxy substituent, making it valuable for drug intermediate synthesis and functional material development. Researchers increasingly explore its potential in targeted drug delivery systems and bioconjugation chemistry, aligning with current trends in precision medicine and green chemistry.

The compound's molecular weight (307.15 g/mol) and lipophilic properties make it particularly useful in designing prodrug formulations, a hot topic in pharmaceutical forums. Its bromine atom provides an excellent handle for cross-coupling reactions, answering frequent search queries about Palladium-catalyzed reactions and Suzuki-Miyaura coupling applications. Recent studies highlight its role in developing fluorescence probes, addressing growing interest in bioimaging techniques and diagnostic tools.

From a synthetic chemistry perspective, 364623-84-7 serves as a versatile building block for creating complex molecular architectures. Its carboxylic acid group enables easy derivatization, frequently discussed in peptide coupling and polymer modification research. The compound's crystalline nature and moderate solubility profile (soluble in DMSO, DMF) make it suitable for high-throughput screening applications, a trending topic in drug discovery communities.

Environmental scientists are investigating 4-(4-bromophenoxy)methylbenzoic acid as a potential biodegradation marker, responding to increased searches about eco-friendly chemical monitoring. Its UV absorption characteristics (λmax ~280 nm) facilitate analytical detection, making it relevant to discussions about HPLC method development and environmental analyte tracking. The compound's thermal stability (decomposition >200°C) also attracts attention in material durability studies.

In regulatory contexts, proper handling of CAS 364623-84-7 requires standard laboratory safety protocols, a frequently searched topic among chemistry professionals. While not classified as hazardous under major chemical inventories, its brominated structure warrants consideration in waste management procedures, aligning with global interest in sustainable chemical practices. The compound's patent landscape shows growing applications in electronic materials and specialty coatings, addressing industry demand for high-performance additives.

Analytical characterization of 4-(4-bromophenoxy)methylbenzoic acid typically involves NMR spectroscopy (1H, 13C), mass spectrometry, and elemental analysis – techniques commonly searched by quality control specialists. Recent publications highlight its potential in metal-organic frameworks (MOFs) construction, tapping into the booming interest in porous materials for gas storage and catalysis. The compound's structure-activity relationships continue to inspire research in medicinal chemistry optimization strategies.

Supply chain data indicates growing availability of 364623-84-7 from specialty chemical suppliers, reflecting increased industrial adoption. Its cost-performance ratio makes it attractive for academic research and small-scale production, addressing common queries about budget-friendly research chemicals. The compound's synthetic versatility positions it as a valuable tool for developing new synthetic methodologies, a perennial focus area in organic chemistry.

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