• 1. An analysis of the WTC fires using CIB correlations and simple modeling
  JGQuintiere
• 2. Aggregated-fluorescent detection of PFAS with a simple chip
  Cheng Fang,Jinjian Wu,Zahra Sobhani,Md. Al Amin,Youhong Tang Anal. Methods, 2019,11, 163-170
• 3. An interplay between electronic and structural effects on the photoluminescence decay mechanisms in LaPO4·nH2O:Tb3+ and LaPO4:Tb3+ single-crystal nanorods?
  M. T. Colomer,S. Díaz-Moreno,A. Tamayo,A. L. Ortiz J. Mater. Chem. C, 2018,6, 12643-12651
• 4. An anti-leakage liquid metal thermal interface material
  Kaiyuan Huang,Wangkang Qiu,Meilian Ou,Xiaorui Liu,Zenan Liao,Sheng Chu RSC Adv., 2020,10, 18824-18829
• 5. An amplified fluorescence detection of T4 polynucleotide kinase activity based on coupled exonuclease III reaction and a graphene oxide platform?
  Ni-Na Sun,Fengli Qu,Xiaobing Zhang,Shufang Zhang,Jinmao You Analyst, 2015,140, 1827-1831

Exploring the Properties and Applications of 4-(5-Methoxy-1H-indol-3-yl)-1,3-thiazol-2-amine (CAS No. 36246-11-4)

The compound 4-(5-Methoxy-1H-indol-3-yl)-1,3-thiazol-2-amine, identified by the CAS registry number CAS No. 36246-11-4, is a fascinating molecule with significant potential in various scientific and industrial applications. This compound belongs to the class of heterocyclic compounds, specifically featuring a thiazole ring system and an indole moiety. The presence of these structural elements contributes to its unique chemical properties and biological activities.

Recent studies have highlighted the importance of thiazole derivatives in drug discovery, particularly in the development of anti-inflammatory, antitumor, and neuroprotective agents. The indole group within this compound further enhances its versatility, as indole-containing molecules are known for their role in modulating various cellular processes. For instance, research published in 2023 demonstrated that analogs of this compound exhibit potent inhibitory effects on key enzymes involved in neurodegenerative diseases, such as acetylcholinesterase and butyrylcholinesterase.

The synthesis of 4-(5-Methoxy-1H-indol-3-yl)-1,3-thiazol-2-amine involves a multi-step process that typically includes the formation of the thiazole ring followed by substitution reactions to introduce the indole moiety. This approach ensures high purity and structural integrity, which are critical for downstream applications. Advanced spectroscopic techniques, such as NMR and mass spectrometry, are employed to confirm the molecular structure and ensure compliance with quality standards.

In terms of biological activity, this compound has shown promise in preclinical studies as a potential therapeutic agent for cancer treatment. Specifically, it has been found to induce apoptosis in various cancer cell lines by targeting key signaling pathways. A study conducted in 2023 revealed that this compound selectively inhibits the proliferation of breast cancer cells while exhibiting minimal toxicity to normal cells, making it a promising candidate for further development.

Beyond its pharmacological applications, CAS No. 36246-11-4 is also being explored for its potential in materials science. Its unique electronic properties make it a suitable candidate for use in organic electronics, such as light-emitting diodes (LEDs) and field-effect transistors (FETs). Researchers have reported that incorporating this compound into polymer blends enhances their electrical conductivity without compromising mechanical stability.

The environmental impact of this compound is another area of growing interest. Studies have shown that it exhibits biodegradability under specific conditions, which is crucial for ensuring its safe disposal and minimizing ecological footprint. However, further research is needed to fully understand its long-term effects on ecosystems.

In conclusion, 4-(5-Methoxy-1H-indol-3-yl)-1,3-thiazol-2-amine (CAS No. 36246–11–4) represents a versatile molecule with diverse applications across multiple disciplines. Its unique chemical structure and promising biological activities position it as a valuable asset in both academic research and industrial development. As ongoing studies continue to uncover new insights into its properties and potential uses, this compound is likely to play an increasingly important role in advancing science and technology.

• 22258-56-6(4-(1H-indol-3-yl)-1,3-thiazol-2-amine)
• 105512-82-1(4-(4-phenoxyphenyl)-1,3-thiazol-2-amine)
• 114196-86-0(2-Thiazolamine,4-(4-methoxyphenyl)-, hydriodide (1:1))
• 873311-81-0(2-Thiazolamine, 4-[5-(3-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-)
• 83558-37-6(4-(3-methoxyphenyl)-1,3-thiazol-2-amine)
• 679390-92-2(8-Quinolinol, 5-(2-amino-4-thiazolyl)-)
• 111317-60-3(2-Thiazolamine, 4-(4-methoxyphenyl)-, monohydrobromide)
• 2104-04-3(4-(4-methoxyphenyl)-1,3-thiazol-2-amine)
• 650626-14-5(2-Thiazolamine, 4-(6-methoxy-1-naphthalenyl)-)
• 189011-04-9(4-(1-methyl-1H-indol-3-yl)-1,3-thiazol-2-amine)