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• 2. Alumina grafted SBA-15 sustainable bifunctional catalysts for direct cross-coupling of benzylic alcohols to diarylmethanes?
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoyl derivatives

Comprehensive Analysis of 3-(3-Bromobenzyl)oxy-4-methoxybenzaldehyde (CAS No. 361465-18-1): Properties, Applications, and Industry Trends

3-(3-Bromobenzyl)oxy-4-methoxybenzaldehyde (CAS No. 361465-18-1) is a specialized organic compound gaining attention in pharmaceutical and material science research. This brominated benzaldehyde derivative features a unique molecular structure combining a methoxybenzaldehyde core with a 3-bromobenzyl ether group, making it valuable for synthetic applications. Researchers frequently search for "3-(3-Bromobenzyl)oxy-4-methoxybenzaldehyde synthesis" or "CAS 361465-18-1 suppliers," reflecting its growing commercial importance.

The compound's electrophilic aldehyde group and aromatic bromine substituent enable diverse chemical transformations, particularly in constructing complex heterocycles. Recent publications highlight its role in developing fluorescent probes and photoactive materials, aligning with the surge in demand for organic electronics. Analytical data shows increasing searches for "3-(3-Bromobenzyl)oxy-4-methoxybenzaldehyde NMR spectrum" and "HPLC purification methods," indicating robust academic interest.

From a commercial perspective, 361465-18-1 serves as a key intermediate in medicinal chemistry, especially for kinase inhibitor development. Its lipophilic nature and hydrogen-bonding capacity make it suitable for drug discovery programs targeting protein-protein interactions. Industry reports note rising queries about "scale-up production" and "regioselective bromination techniques," reflecting manufacturing challenges.

Environmental and regulatory aspects of 3-(3-Bromobenzyl)oxy-4-methoxybenzaldehyde comply with major chemical inventories (REACH, TSCA). The compound's stability profile and low ecotoxicity make it preferable to heavier halogenated analogs, addressing sustainability concerns in green chemistry initiatives. Search trends reveal growing interest in "biodegradable benzaldehyde derivatives" and "halogenated compound alternatives."

Advanced characterization studies using X-ray crystallography and DFT calculations have elucidated the compound's conformational preferences, important for rational drug design. The crystal packing of 361465-18-1 shows interesting π-π stacking interactions, relevant to materials science applications. Researchers increasingly seek "solid-state properties" and "polymorphism studies" related to this compound.

In analytical chemistry, 3-(3-Bromobenzyl)oxy-4-methoxybenzaldehyde serves as a chromatographic standard for method development. Its distinct UV absorption maxima at 254 nm and 310 nm facilitate detection in complex matrices. Laboratory professionals frequently inquire about "HPLC retention time" and "mass spectrometry fragmentation patterns" for this analyte.

The future outlook for CAS 361465-18-1 appears promising, particularly in catalysis research and functional material synthesis. Emerging applications in metal-organic frameworks (MOFs) and covalent organic polymers (COPs) demonstrate its versatility. Patent analysis reveals growing IP activity around "bromobenzyl ether derivatives" and "methoxybenzaldehyde applications," signaling continued commercial relevance.

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• 352455-48-2(4-(4-Bromobenzyl)oxy-3-methoxybenzaldehyde)
• 443292-05-5(4-(4-Bromobenzyl)oxy-3-ethoxybenzaldehyde)
• 168084-97-7(3-(4-Bromobenzyl)oxybenzaldehyde)
• 697302-70-8(Benzaldehyde, 5-bromo-2-hydroxy-3-(phenylmethoxy)-)
• 2556-04-9(4-(Benzyloxy)-3-bromo-5-methoxybenzaldehyde)
• 667437-48-1(2-(3-Bromobenzyl)oxy-3-methoxybenzaldehyde)
• 428476-06-6(4-(BENZYLOXY)-3-BROMO-5-ETHOXYBENZALDEHYDE)
• 137489-76-0(3-(3-Bromobenzyl)oxybenzaldehyde)
• 588676-02-2(4-(3-Bromobenzyl)oxybenzaldehyde)