Cas no 359860-27-8 (Amine-PEG3-Biotin)
Amine-PEG3-Biotin is a heterobifunctional crosslinker featuring a primary amine group and a biotin moiety connected by a triethylene glycol (PEG3) spacer. The amine group enables conjugation with carboxyls, carbonyls, or other reactive groups, while the biotin tag facilitates strong, specific binding to streptavidin or avidin for detection or purification. The PEG3 spacer enhances solubility, reduces steric hindrance, and improves biocompatibility. This reagent is particularly useful for bioconjugation in applications such as protein labeling, surface modification, and affinity-based assays. Its well-defined structure and reliable reactivity make it a valuable tool for researchers in biochemistry, molecular biology, and diagnostics.
Amine-PEG3-Biotin structure
Product Name:Amine-PEG3-Biotin
CAS No:359860-27-8
MF:C18H34N4O5S
MW:418.5514
MDL:MFCD09952640
CID:920914
PubChem ID:125307160
Update Time:2025-06-07
Amine-PEG3-Biotin Chemical and Physical Properties
Names and Identifiers
-
- N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE
- Biotin-PEG3-Amine
- (+)-BIOTIN-(PEO)4-AMINE
- (+)-Biotin-PEG3-amine
- (+)-Biotin-PEG3-CH2CH2NH2
- (+)-Biotinyl 3,6,9-Trioxaundecanediamine
- N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-5-[(4S)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanamide
- (+)-biotin-(PEO)4-NH2
- (+)-Biotin-PEG<SUB>3<
- 1H-Thieno[3,4-d]imidazole-4-pentanamide,N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]
- amine-PEG3-biotin
- amine-PEO3-biotin
- Biotin-LC-PEO-Amine
- Biotin-LC-PEO-NH2
- biotin-PEO-LC-amine
- N-(2-[2-{2-(2-aminoethoxy)ethoxy}ethoxy]ethyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide
- SUB>-amine
- N-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethyl]biotinamide
- (+)-Biotin-PEG3-NH2
- BIPG1208
- C18H34N4O5S
- 7525AH
- 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethyl)pentanamide
- (3aS,4S,6aR)-N-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide; EZ-Link Amine-PEO3-Biotin; EZ-Link Biotin-PEO-LC Amine
- (+)-Biotinyl3,6,9-trioxaundecanediamine
- UNII-IAF990JL4X
- PD078472
- Biotin-PEG3-CH2CH2NH2
- H10311
- N-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
- DA-50400
- IAF990JL4X
- 359860-27-8
- HY-111377
- CS-0040256
- LCZC2665
- MFCD09952640
- EZ-LINK Biotin-PEG3-amine
- BP-22826
- (+)-Biotin-PEG?-amine
- AKOS005166837
- 5-[(3AS,4S,6AR)-2-OXO-HEXAHYDROTHIENO[3,4-D]IMIDAZOL-4-YL]-N-(2-{2-[2-(2-AMINOETHOXY)ETHOXY]ETHOXY}ETHYL)PENTANAMIDE
- 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]pentanamide
- SCHEMBL4334915
- amine-PEG-3-biotin
- Biotin-PEG3-NH2
- EX-A4438
- AS-66192
- (3aS,4S,6aR)-N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)hexahydro-2-oxo-1H-thieno(3,4-d)imidazole-4-pentanamide
- Amine-PEG3-Biotin
-
- MDL： MFCD09952640
- Inchi： 1S/C18H34N4O5S/c19-5-7-25-9-11-27-12-10-26-8-6-20-16(23)4-2-1-3-15-17-14(13-28-15)21-18(24)22-17/h14-15,17H,1-13,19H2,(H,20,23)(H2,21,22,24)/t14-,15-,17-/m0/s1
- InChI Key： KIJSBKNJFAUJFV-ZOBUZTSGSA-N
- SMILES： S1C([H])([H])[C@@]2([H])[C@@]([H])([C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(N([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])[H])=O)N([H])C(N2[H])=O
Computed Properties
- Exact Mass: 418.22500
- Monoisotopic Mass: 418.22499137g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 4
- Hydrogen Bond Acceptor Count: 7
- Heavy Atom Count: 28
- Rotatable Bond Count: 16
- Complexity: 471
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 2
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: 6
- XLogP3: -1.3
- Topological Polar Surface Area: 149
Experimental Properties
- Color/Form: Solid
- Density: 1.166±0.06 g/cm3 (20 oC 760 Torr),
- Melting Point: No data available
- Boiling Point: 705.8±60.0 °C at 760 mmHg
- Flash Point: 380.6±32.9 °C
- Solubility: Very slightly soluble (0.75 g/l) (25 o C),
- PSA: 156.22000
- LogP: 1.34630
- Vapor Pressure: 0.0±2.2 mmHg at 25°C
Amine-PEG3-Biotin Security Information
- Signal Word：warning
- Hazard Statement： H303 may be harmful by ingestion +h313 may be harmful by skin contact +h2413 may be harmful by inhalation
-
Warning Statement：
P264 wash thoroughly after treatment
p280 wear protective gloves / wear protective clothing / wear protective eye masks / wear protective masks
p305 if in eyes
p351 rinse carefully with water for a few minutes
p338 remove contact lenses (if any) and easy to operate, continue rinsing
p337 if eye irritation persists
p2393 get medical advice / care - Safety Instruction： H303 may be harmful by ingestion +h313 may be harmful by skin contact +h2413 may be harmful by inhalation
- Storage Condition：Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month
Amine-PEG3-Biotin Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| MedChemExpress | HY-111377-10mM*1mLinDMSO |
Amine-PEG3-Biotin |
359860-27-8 | 98.08% | 10mM*1mLinDMSO |
￥660 | 2023-07-26 | |
| MedChemExpress | HY-111377-5mg |
Amine-PEG3-Biotin |
359860-27-8 | 99.79% | 5mg |
￥100 | 2025-04-16 | |
| MedChemExpress | HY-111377-10mg |
Amine-PEG3-Biotin |
359860-27-8 | 99.79% | 10mg |
￥150 | 2025-04-16 | |
| MedChemExpress | HY-111377-25mg |
Amine-PEG3-Biotin |
359860-27-8 | 99.79% | 25mg |
￥300 | 2025-04-16 | |
| MedChemExpress | HY-111377-50mg |
Amine-PEG3-Biotin |
359860-27-8 | 99.79% | 50mg |
￥484 | 2025-04-16 | |
| MedChemExpress | HY-111377-100mg |
Amine-PEG3-Biotin |
359860-27-8 | 99.79% | 100mg |
￥736 | 2025-04-16 | |
| Alichem | A449039975-1g |
N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide |
359860-27-8 | 95% | 1g |
$785.00 | 2023-09-02 | |
| Ambeed | A444152-50mg |
N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide |
359860-27-8 | 95% | 50mg |
$55.0 | 2025-02-28 | |
| Ambeed | A444152-100mg |
N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide |
359860-27-8 | 95% | 100mg |
$69.0 | 2025-02-28 | |
| Ambeed | A444152-250mg |
N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide |
359860-27-8 | 95% | 250mg |
$109.0 | 2025-02-28 |
Amine-PEG3-Biotin Related Literature
-
Erika A. Cobar,Paul R. Horn,Robert G. Bergman,Martin Head-Gordon Phys. Chem. Chem. Phys., 2012,14, 15328-15339
-
Shaun D. Wong,Edward I. Solomon Dalton Trans., 2014,43, 17567-17577
-
Jacob S. Jordan,Evan R. Williams Analyst, 2021,146, 2617-2625
-
Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
-
Partha Laskar,Christine Dufès Nanoscale Adv., 2021,3, 6007-6026
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