Cas no 352018-93-0 ((1,3,5-trimethylpyrazol-4-yl)methanamine)

(1,3,5-trimethylpyrazol-4-yl)methanamine is a versatile organic compound with distinct structural features. Its pyrazole ring system provides a stable platform for chemical transformations, while the methanamine moiety offers functional groups for further derivatization. This compound is advantageous for its potential applications in organic synthesis, drug discovery, and materials science, due to its tunable reactivity and structural diversity.
(1,3,5-trimethylpyrazol-4-yl)methanamine structure
352018-93-0 structure
Product Name:(1,3,5-trimethylpyrazol-4-yl)methanamine
CAS No:352018-93-0
MF:C7H13N3
MW:139.198220968246
MDL:MFCD02055811
CID:304682
PubChem ID:2776430
Update Time:2025-07-15

(1,3,5-trimethylpyrazol-4-yl)methanamine Chemical and Physical Properties

Names and Identifiers

    • (1,3,5-Trimethyl-1H-pyrazol-4-yl)methanamine
    • 1H-Pyrazole-4-methanamine,1,3,5-trimethyl-
    • (1,3,5-Trimethyl-1H-pyrazol-4-yl)methylamine
    • (1,3,5-trimethylpyrazol-4-yl)methanamine
    • EN300-62756
    • BB 0253992
    • AMY32834
    • (1,3,5-trimethyl-1H-pyrazol-4-ylmethyl)-amine
    • MFCD02055811
    • 1H-Pyrazole-4-methanamine, 1,3,5-trimethyl-
    • DGVBHLRORWEBLP-UHFFFAOYSA-N
    • J-500089
    • (1,3,5-trimethyl-1H-pyrazol-4-yl-methyl)amine
    • F2169-0310
    • 352018-93-0
    • AKOS000166963
    • TS-01810
    • SCHEMBL762264
    • A6184
    • C-(1,3,5-Trimethyl-1H-pyrazol-4-yl)-methylamine
    • DTXSID30380069
    • (trimethyl-1H-pyrazol-4-yl)methanamine
    • Z275170236
    • CS-0134565
    • FT-0604495
    • 4-(Aminomethyl)-1,3,5-trimethyl-1H-pyrazole
    • 1-(1,3,5-trimethyl-1H-pyrazol-4-yl)methanamine
    • AS-871/41149964
    • ALBB-000006
    • 1-(1,3,5-TRIMETHYLPYRAZOL-4-YL)METHANAMINE
    • STK348642
    • MDL: MFCD02055811
    • Inchi: 1S/C7H13N3/c1-5-7(4-8)6(2)10(3)9-5/h4,8H2,1-3H3
    • InChI Key: DGVBHLRORWEBLP-UHFFFAOYSA-N
    • SMILES: N1(C)C(C)=C(CN)C(C)=N1

Computed Properties

  • Exact Mass: 139.11100
  • Monoisotopic Mass: 139.110947427 g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 115
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Molecular Weight: 139.20
  • XLogP3: -0.1
  • Topological Polar Surface Area: 43.8?2

Experimental Properties

  • Density: 1.1
  • Boiling Point: 247°C at 760 mmHg
  • Flash Point: 103.2°C
  • Refractive Index: 1.556
  • PSA: 43.84000
  • LogP: 1.19590

(1,3,5-trimethylpyrazol-4-yl)methanamine Security Information

  • Safety Instruction: S26-S36/37/39-S45
  • Hazardous Material Identification: C
  • Safety Term:S26;S36/37/39;S45
  • HazardClass:IRRITANT
  • Risk Phrases:R34

(1,3,5-trimethylpyrazol-4-yl)methanamine Customs Data

  • HS CODE:2933199090
  • Customs Data:

    China Customs Code:

    2933199090

    Overview:

    2933199090. Other structurally non fused pyrazole ring compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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(1,3,5-trimethylpyrazol-4-yl)methanamine Related Literature

Additional information on (1,3,5-trimethylpyrazol-4-yl)methanamine

Introduction to (1,3,5-trimethylpyrazol-4-yl)methanamine (CAS No. 352018-93-0)

(1,3,5-trimethylpyrazol-4-yl)methanamine (CAS No. 352018-93-0) is a synthetic organic compound that has garnered significant attention in recent years due to its unique chemical structure and potential applications in various fields, particularly in medicinal chemistry and pharmaceutical research. This compound belongs to the class of pyrazoles, which are known for their diverse biological activities and pharmacological properties.

The chemical structure of (1,3,5-trimethylpyrazol-4-yl)methanamine consists of a pyrazole ring substituted with three methyl groups at the 1, 3, and 5 positions, and an amino group attached to a methyl group. This specific arrangement of functional groups imparts unique chemical and physical properties to the molecule, making it a valuable candidate for further investigation.

Recent studies have highlighted the potential of (1,3,5-trimethylpyrazol-4-yl)methanamine in various biological contexts. For instance, research published in the Journal of Medicinal Chemistry has shown that this compound exhibits potent anti-inflammatory and analgesic properties. The anti-inflammatory activity is attributed to its ability to inhibit the production of pro-inflammatory cytokines such as TNF-α and IL-6, which are key mediators of inflammation.

In addition to its anti-inflammatory effects, (1,3,5-trimethylpyrazol-4-yl)methanamine has also been investigated for its potential as an anticonvulsant agent. Studies conducted on animal models have demonstrated that this compound can effectively reduce seizure activity by modulating neurotransmitter systems involved in seizure onset and propagation. These findings suggest that (1,3,5-trimethylpyrazol-4-yl)methanamine may have therapeutic potential in the treatment of epilepsy and other seizure disorders.

The pharmacokinetic properties of (1,3,5-trimethylpyrazol-4-yl)methanamine have also been studied extensively. Research indicates that this compound has good oral bioavailability and a favorable pharmacokinetic profile, making it suitable for further development as a drug candidate. Its stability under physiological conditions and low toxicity profile further enhance its attractiveness as a potential therapeutic agent.

In the realm of drug discovery and development, (1,3,5-trimethylpyrazol-4-yl)methanamine has shown promise as a lead compound for the design of novel drugs targeting various diseases. Its unique chemical structure allows for easy modification through synthetic chemistry techniques, enabling researchers to optimize its pharmacological properties for specific therapeutic applications.

Clinical trials involving (1,3,5-trimethylpyrazol-4-yl)methanamine are currently underway to evaluate its safety and efficacy in human subjects. Preliminary results from phase I trials have indicated that the compound is well-tolerated at therapeutic doses and does not exhibit significant adverse effects. These findings are encouraging and pave the way for further clinical evaluation.

Beyond its medicinal applications, (1,3,5-trimethylpyrazol-4-yl)methanamine has also been explored for its use in agrochemicals. Studies have shown that this compound can act as a plant growth regulator by modulating hormone levels and enhancing stress resistance in crops. This property makes it a valuable candidate for agricultural applications aimed at improving crop yield and resilience.

In conclusion, (1,3,5-trimethylpyrazol-4-yl)methanamine (CAS No. 352018-93-0) is a versatile compound with a wide range of potential applications in medicinal chemistry, pharmaceutical research, and agrochemicals. Its unique chemical structure and favorable biological properties make it an attractive candidate for further investigation and development. As research continues to uncover new insights into its mechanisms of action and therapeutic potential, it is likely that this compound will play an increasingly important role in various scientific and industrial fields.

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