Cas no 351003-49-1 (5-chloro-2-fluorobenzene-1-sulfonyl chloride)

5-Chloro-2-fluorobenzene-1-sulfonyl chloride is a versatile sulfonylating agent used in organic synthesis and pharmaceutical intermediates. Its key advantages include high reactivity due to the sulfonyl chloride functional group, enabling efficient introduction of the sulfonyl moiety into target molecules. The chloro and fluoro substituents enhance its utility in fine chemical applications, offering selective reactivity for further derivatization. This compound is particularly valuable in the preparation of sulfonamides, sulfonate esters, and other sulfur-containing compounds. Its stability under controlled conditions ensures reliable handling and storage. Suitable for use in research and industrial settings, it serves as a key building block in medicinal chemistry and agrochemical development.

5-chloro-2-fluorobenzene-1-sulfonyl chloride structure

351003-49-1 structure

Product Name:5-chloro-2-fluorobenzene-1-sulfonyl chloride

CAS No:351003-49-1

MF:C₆H₃Cl₂FO₂S

MW:229.056222200394

MDL:MFCD03094221

CID:92792

PubChem ID:24879766

Update Time:2025-06-08

5-chloro-2-fluorobenzene-1-sulfonyl chloride Chemical and Physical Properties

Names and Identifiers

- 5-Chloro-2-fluorobenzene-1-sulfonyl chloride
- 5-CHLORO-2-FLUOROBENZENESULFONYL CHLORIDE
- 5-CHLORO-2-FLUOROBENZENESULPHONYL CHLORIDE
- 5-CHLORO-2-FLUOROBENZENSULPHONYL CHLORIDE
- 5-CHLORO-2-FLUOROBENZENESULFONYL CHLORI&
- Benzenesulfonyl chloride, 5-chloro-2-fluoro- (9CI)
- 5-CHLORO-2-FLUOROBENZENSULFONYL CHLORIDE
- 3-chloro-6-fluorobenzenesulfonyl chloride
- 5-chloro-2-fluoro-benzenesulfonyl Chloride
- 5-chloro-2-fluorophenylsulfonyl chloride
- PubChem5094
- 5-chloro-2-fluorobenzenesulfonylchloride
- Benzenesulfonyl chloride, 5-chloro-2-fluoro-
- OZKAHSNNKADHTK-UHFFFAOYSA-N
- SBB066481
- VZ30198
- TRA0056192
- chloro(5-chloro-2-fluoropheny
- 5-Chloro-2-fluorobenzenesulfonyl chloride, 97%
- CS-W012986
- PS-10901
- 5-chloranyl-2-fluoranyl-benzenesulfonyl chloride
- A822558
- DTXSID50380844
- SCHEMBL533050
- FT-0620241
- AMY40556
- AKOS000142313
- 351003-49-1
- J-019926
- MFCD03094221
- EN300-87064
- A12448
- DB-037967
- 5-chloro-2-fluorobenzene-1-sulfonyl chloride
- MDL： MFCD03094221
- Inchi： 1S/C6H3Cl2FO2S/c7-4-1-2-5(9)6(3-4)12(8,10)11/h1-3H
- InChI Key： OZKAHSNNKADHTK-UHFFFAOYSA-N
- SMILES： ClS(C1C(=CC=C(C=1)Cl)F)(=O)=O

Computed Properties

Exact Mass: 227.92100
Monoisotopic Mass: 227.921
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Heavy Atom Count: 12
Rotatable Bond Count: 1
Complexity: 249
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Surface Charge: 0
Tautomer Count: nothing
XLogP3: 2.7
Topological Polar Surface Area: 42.5

Experimental Properties

Color/Form: White or cream crystals
Density: 1.61
Melting Point: 41-44?°C (lit.)
Boiling Point: 283.6 ℃ at 760 mmHg
Flash Point: >110°(230℉)(lit.)
Refractive Index: 1.55
PSA: 42.52000
LogP: 3.48740
Sensitiveness: Moisture Sensitive
Solubility: React with water

5-chloro-2-fluorobenzene-1-sulfonyl chloride Security Information

Symbol:
Signal Word：Danger
Hazard Statement： H314
Warning Statement： P280-P305+P351+P338-P310
Hazardous Material transportation number：UN 3261 8/PG 2
WGK Germany：3
Hazard Category Code： 14-34
Safety Instruction： S22-S26-S36/37/39-S45
Hazardous Material Identification：
HazardClass：8
PackingGroup：II
Storage Condition：Inert atmosphere,2-8°C(BD3135)
Packing Group：II
Hazard Level：8
Safety Term：8
Packing Group：II
Risk Phrases：R14

5-chloro-2-fluorobenzene-1-sulfonyl chloride Customs Data

HS CODE：2904909090
Customs Data：

China Customs Code:
2904909090

Overview:

2904909090 Sulfonation of other hydrocarbons\nitrification\Nitrosative derivative(Whether halogenated or not). VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:5.5% general tariff:30.0%

Declaration elements:

Product Name, component content, use to

Summary:

HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

5-chloro-2-fluorobenzene-1-sulfonyl chloride Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
Fluorochem	013075-1g	5-Chloro-2-fluorobenzenesulfonyl chloride	351003-49-1	97%	1g	￡10.00	2022-03-01
Fluorochem	013075-5g	5-Chloro-2-fluorobenzenesulfonyl chloride	351003-49-1	97%	5g	￡14.00	2022-03-01
Fluorochem	013075-25g	5-Chloro-2-fluorobenzenesulfonyl chloride	351003-49-1	97%	25g	￡53.00	2022-03-01
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	C138712-1g	5-chloro-2-fluorobenzene-1-sulfonyl chloride	351003-49-1	≥97%	1g	￥87.90	2023-09-03
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	C138712-25g	5-chloro-2-fluorobenzene-1-sulfonyl chloride	351003-49-1	≥97%	25g	￥1100.90	2023-09-03
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.	C138712-5g	5-chloro-2-fluorobenzene-1-sulfonyl chloride	351003-49-1	≥97%	5g	￥275.90	2023-09-03
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.	R001413-1g	5-chloro-2-fluorobenzene-1-sulfonyl chloride	351003-49-1	98%	1g	￥68	2024-05-24
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.	R001413-5g	5-chloro-2-fluorobenzene-1-sulfonyl chloride	351003-49-1	98%	5g	￥96	2024-05-24
TRC	C584890-2.5g	5-Chloro-2-fluorobenzenesulfonyl chloride	351003-49-1		2.5g	$64.00	2023-05-18
TRC	C584890-5g	5-Chloro-2-fluorobenzenesulfonyl chloride	351003-49-1		5g	$75.00	2023-05-18

5-chloro-2-fluorobenzene-1-sulfonyl chloride Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd

Gold Member

Audited Supplier

(CAS:351003-49-1)5-氯-2-氟苯磺酰基氯

Order Number:LE1748408

Stock Status:in Stock

Quantity:25KG,200KG,1000KG

Purity:99%

Pricing Information Last Updated:Friday, 20 June 2025 12:35

Price ($):discuss personally

Email:[email protected]

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Related Categories

Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzenesulfonyl compounds Benzenesulfonyl halides

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Tiancheng Chemical (Jiangsu) Co., Ltd

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