Cas no 350997-56-7 (3-Methylthiophene-2-carbohydrazide)

3-Methylthiophene-2-carbohydrazide structure
350997-56-7 structure
Product Name:3-Methylthiophene-2-carbohydrazide
CAS No:350997-56-7
MF:C6H8N2OS
MW:156.205519676208
MDL:MFCD01993658
CID:873537
PubChem ID:2760084
Update Time:2025-10-29

3-Methylthiophene-2-carbohydrazide Chemical and Physical Properties

Names and Identifiers

    • 3-Methylthiophene-2-carbohydrazide
    • 3-methyl-2-thiophenecarbohydrazide
    • 3-Methyl-thiophene-2-carboxylic acid hydrazide
    • AC1MC1VR
    • AC1Q2GHN
    • ALBB-002529
    • CTK7F0955
    • MolPort-000-157-561
    • SureCN2482673
    • BBL016100
    • MVROGAXPQMISQI-UHFFFAOYSA-N
    • CS-0217030
    • VS-05138
    • DTXSID30375016
    • EN300-66540
    • 2-Thiophenecarboxylicacid,3-methyl-,hydrazide(9CI)
    • G19201
    • MFCD01993658
    • SY079881
    • SB85969
    • SCHEMBL2482673
    • AKOS000184650
    • VTT
    • 350997-56-7
    • STK317643
    • MDL: MFCD01993658
    • Inchi: 1S/C6H8N2OS/c1-4-2-3-10-5(4)6(9)8-7/h2-3H,7H2,1H3,(H,8,9)
    • InChI Key: MVROGAXPQMISQI-UHFFFAOYSA-N
    • SMILES: S1C=CC(C)=C1C(NN)=O

Computed Properties

  • Exact Mass: 156.03584
  • Monoisotopic Mass: 156.036
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 2
  • Complexity: 140
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.8
  • Topological Polar Surface Area: 83.4?2

Experimental Properties

  • Density: 1.273
  • Refractive Index: 1.6
  • PSA: 55.12

3-Methylthiophene-2-carbohydrazide Security Information

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Additional information on 3-Methylthiophene-2-carbohydrazide

3-Methylthiophene-2-carbohydrazide (CAS No. 350997-56-7): Properties, Applications, and Market Insights

3-Methylthiophene-2-carbohydrazide (CAS No. 350997-56-7) is a specialized organic compound that has garnered significant attention in pharmaceutical and agrochemical research. This heterocyclic compound belongs to the thiophene family, characterized by a five-membered ring containing sulfur. The presence of both methyl and carbohydrazide functional groups makes it a versatile building block for various synthetic applications.

The molecular structure of 3-Methylthiophene-2-carbohydrazide offers unique reactivity patterns that researchers are actively exploring. Recent studies highlight its potential as a precursor for heterocyclic drug development, particularly in creating novel antimicrobial agents and enzyme inhibitors. The compound's thiophene core contributes to its electron-rich properties, which are valuable in designing pharmaceutical intermediates with improved bioavailability.

In the context of current research trends, 3-Methylthiophene-2-carbohydrazide aligns with the growing demand for sustainable chemistry solutions. Scientists are investigating its role in green synthesis methods, where its relatively stable nature allows for milder reaction conditions compared to traditional alternatives. This aspect is particularly relevant as the chemical industry shifts toward eco-friendly production processes.

The compound's physical and chemical properties make it suitable for various laboratory applications. With a molecular weight of 156.21 g/mol, 3-Methylthiophene-2-carbohydrazide typically appears as a white to off-white crystalline powder. Its solubility profile shows moderate dissolution in polar organic solvents while being less soluble in water, a characteristic that researchers consider when designing reaction systems.

Market analysis indicates rising interest in thiophene derivatives like 3-Methylthiophene-2-carbohydrazide, driven by expanding pharmaceutical R&D budgets worldwide. The compound's structural versatility allows for diverse modifications, making it valuable for medicinal chemistry applications. Industry reports suggest that the global market for such specialized heterocyclic compounds will continue growing at a steady pace through 2030.

Quality control measures for 3-Methylthiophene-2-carbohydrazide typically involve advanced analytical techniques. High-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy are commonly employed to verify purity and structural integrity. These rigorous standards ensure the compound meets the requirements for research-grade chemicals in academic and industrial settings.

From a safety perspective, proper handling procedures should be followed when working with 3-Methylthiophene-2-carbohydrazide. While not classified as highly hazardous, standard laboratory precautions including proper ventilation and personal protective equipment are recommended. Material Safety Data Sheets (MSDS) provide detailed guidance on storage conditions and handling protocols for this compound.

The synthesis of 3-Methylthiophene-2-carbohydrazide typically involves multi-step organic reactions starting from commercially available thiophene precursors. Recent advancements in catalytic processes have improved the yield and purity of the final product. These methodological improvements contribute to the compound's increasing availability for research purposes.

In the pharmaceutical sector, 3-Methylthiophene-2-carbohydrazide has shown promise as a scaffold for developing new bioactive molecules. Its molecular framework allows for strategic modifications that can enhance binding affinity to biological targets. This characteristic is particularly valuable in drug discovery programs targeting infectious diseases and metabolic disorders.

The compound's relevance extends to material science applications as well. Researchers are exploring its potential in developing organic electronic materials, where the thiophene moiety contributes to charge transport properties. This interdisciplinary application demonstrates the broad utility of 3-Methylthiophene-2-carbohydrazide across scientific fields.

As analytical techniques advance, new characterization data for 3-Methylthiophene-2-carbohydrazide continues to emerge. Recent publications have provided more detailed insights into its spectroscopic properties and crystalline structure. These findings help researchers better understand the compound's behavior in various chemical environments.

Looking ahead, the scientific community anticipates expanded applications for 3-Methylthiophene-2-carbohydrazide in emerging fields such as bioconjugation chemistry and molecular imaging. The compound's functional groups offer multiple sites for selective modification, making it adaptable to cutting-edge research needs. This flexibility positions it as a valuable tool for future chemical innovations.

For researchers sourcing 3-Methylthiophene-2-carbohydrazide, it's important to verify supplier credentials and product specifications. Reputable chemical suppliers typically provide batch-specific analytical data and proper documentation. The compound is generally available in research quantities, with lead times varying based on current demand and production schedules.

In conclusion, 3-Methylthiophene-2-carbohydrazide (CAS No. 350997-56-7) represents an important heterocyclic building block with diverse applications in modern chemistry. Its unique structural features and reactivity profile continue to inspire innovative research across multiple disciplines. As scientific understanding of this compound grows, so too does its potential to contribute to significant advancements in pharmaceutical and material sciences.

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