Cas no 35046-68-5 (Tetramethylsuccinic anhydride)

Tetramethylsuccinic anhydride (TMSA) is a cyclic dicarboxylic anhydride with the molecular formula C8H12O3. It is characterized by its four methyl groups attached to the succinic anhydride backbone, enhancing steric hindrance and influencing reactivity. TMSA is primarily used as an intermediate in organic synthesis, particularly in the production of specialty polymers, resins, and fine chemicals. Its rigid structure contributes to improved thermal stability and mechanical properties in polymer applications. The anhydride functionality allows for reactions with nucleophiles, such as amines or alcohols, enabling crosslinking or functionalization. TMSA is valued for its purity, consistent performance, and suitability in high-precision chemical processes.
Tetramethylsuccinic anhydride structure
Tetramethylsuccinic anhydride structure
Product Name:Tetramethylsuccinic anhydride
CAS No:35046-68-5
MF:C8H12O3
MW:156.179082870483
MDL:MFCD00829208
CID:316385
PubChem ID:141941
Update Time:2025-10-13

Tetramethylsuccinic anhydride Chemical and Physical Properties

Names and Identifiers

    • 2,5-Furandione,dihydro-3,3,4,4-tetramethyl-
    • 3,3,4,4-tetramethyloxolane-2,5-dione
    • 2, dihydro-3,3,4,4-tetramethyl-
    • 2,2,3,3-tetramethylsuccinic anhydride
    • 3,3,4,4-tetramethylsuccinic anhydride
    • AC1L3K4B
    • CTK4H3447
    • Dihydro-3,3,4,4-tetramethyl-2,5-furandione
    • NCIOpen2_001580
    • NSC92363
    • teteramethylsuccinic anhydride
    • Tetramethyl-bernsteinsaeure-anhydrid
    • tetramethyl-succinic acid anhydride
    • Tetramethylsuccinic anhydride
    • 3,3,4,4-Tetramethyldihydrofuran-2,5-dione
    • MDL: MFCD00829208
    • Inchi: 1S/C8H12O3/c1-7(2)5(9)11-6(10)8(7,3)4/h1-4H3
    • InChI Key: KYZIXHLDWJBHDI-UHFFFAOYSA-N
    • SMILES: O1C(C(C)(C)C(C)(C)C1=O)=O

Computed Properties

  • Exact Mass: 156.07866
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 0

Experimental Properties

  • PSA: 43.37

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Tetramethylsuccinic anhydride Related Literature

Additional information on Tetramethylsuccinic anhydride

2,5-Furandione, dihydro-3,3,4,4-tetramethyl- (CAS No: 35046-68-5)

The compound 2,5-furandione, dihydro-3,3,4,4-tetramethyl- (CAS No: 35046-68-5) is a fascinating organic molecule with a unique structure and diverse applications. This compound belongs to the class of furan derivatives and has garnered significant attention in recent years due to its versatile properties and potential uses in various industries. The molecule consists of a furan ring with two ketone groups at positions 2 and 5 and four methyl groups attached to the dihydro positions at carbons 3 and 4. This arrangement imparts the compound with distinctive chemical and physical properties.

Recent studies have highlighted the biological activity of 2,5-furandione derivatives, particularly their role as antioxidants and anti-inflammatory agents. Researchers have explored the potential of this compound in the development of novel therapeutic agents for conditions such as neurodegenerative diseases and cardiovascular disorders. The methyl groups in the molecule contribute to its stability and solubility, making it an ideal candidate for pharmacological applications.

In the food industry, 2,5-furandione derivatives are widely used as flavor enhancers due to their ability to impart a pleasant taste profile to food products. The compound's aromatic properties make it particularly effective in enhancing the flavor of baked goods and beverages. Recent advancements in food chemistry have led to the development of more efficient methods for synthesizing this compound at an industrial scale.

The synthesis of 2,5-furandione, dihydro-3,3,4,4-tetramethyl- involves a multi-step process that typically begins with the oxidation of suitable furan precursors. Researchers have optimized reaction conditions to improve yield and purity. For instance, recent studies have demonstrated the use of microwave-assisted synthesis to accelerate the reaction process while maintaining product quality.

Environmental applications of this compound are another area of active research. Due to its ability to act as a biodegradable additive, it has been explored for use in eco-friendly packaging materials and biodegradable plastics. Scientists are investigating ways to enhance its biodegradability further while retaining its functional properties.

In conclusion, 2,5-furandione derivatives represent a promising class of compounds with applications across multiple industries. Ongoing research continues to uncover new potential uses for this compound while improving its synthesis and application methods. As advancements in chemistry and materials science progress, it is likely that this compound will play an increasingly important role in both industrial and therapeutic contexts.

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