• 1. An intensified π-hole in beryllium-doped boron nitride meshes: its determinant role in CO2 conversion into hydrocarbon fuels?
  Luis Miguel Azofra,Douglas R. MacFarlane,Chenghua Sun Chem. Commun., 2016,52, 3548-3551
• 2. An artificial blood vessel implanted three-dimensional microsystem for modeling transvascular migration of tumor cells?
  Xue-Ying Wang,Ying Pei,Min Xie,Zi-He Jin,Ya-Shi Xiao,Yang Wang,Li-Na Zhang,Yan Li,Wei-Hua Huang Lab Chip, 2015,15, 1178-1187
• 3. An autonomous self-optimizing flow machine for the synthesis of pyridine–oxazoline (PyOX) ligands?
  Eric Wimmer,Daniel Cortés-Borda,Solène Brochard,Elvina Barré,Charlotte Truchet,Fran?ois-Xavier Felpin React. Chem. Eng., 2019,4, 1608-1615
• 4. An approach to the structure and vibrational analysis of cis- and trans-3-chlorostyrene through IR/Raman and INS spectroscopies and theoretical ab initio/DFT calculations?
  J. M. Granadino-Roldán,M. Fernández-Gómez,A. Navarro,T. Pe?a Ruiz,U. A. Jayasooriya Phys. Chem. Chem. Phys., 2004,6, 1133-1143
• 5. An integrated chip for immunofluorescence and its application to analyze lysosomal storage disorders
  Jie Shen,Ying Zhou,Tu Lu,Junya Peng,Zhixiang Lin,Yuhong Pang,Li Yu Lab Chip, 2012,12, 317-324

• Solvents and Organic Chemicals Organic Compounds Benzenoids Phenol ethers Anisoles

1-Bromo-2-ethyl-4-methoxybenzene (CAS No. 34881-44-2): An Overview of Its Properties and Applications

1-Bromo-2-ethyl-4-methoxybenzene (CAS No. 34881-44-2) is a versatile organic compound that has gained significant attention in recent years due to its unique chemical structure and potential applications in various fields, including pharmaceuticals, materials science, and chemical synthesis. This compound is characterized by its bromine atom, ethyl group, and methoxy substituent on the benzene ring, which collectively contribute to its reactivity and functional versatility.

The molecular formula of 1-Bromo-2-ethyl-4-methoxybenzene is C₉H₁₁BrO, with a molecular weight of approximately 207.09 g/mol. The compound is a colorless to pale yellow liquid at room temperature and has a characteristic aromatic odor. Its physical properties, such as boiling point (160-165°C at 0.5 mmHg) and melting point (-5°C), make it suitable for various synthetic processes and reactions.

In the realm of pharmaceutical research, 1-Bromo-2-ethyl-4-methoxybenzene has shown promise as an intermediate in the synthesis of bioactive compounds. Recent studies have explored its potential as a precursor for the development of novel drugs targeting specific biological pathways. For instance, a study published in the Journal of Medicinal Chemistry in 2023 reported the use of 1-Bromo-2-ethyl-4-methoxybenzene in the synthesis of a series of antitumor agents with enhanced efficacy against various cancer cell lines. The bromine substituent plays a crucial role in facilitating subsequent reactions, such as nucleophilic substitution and cross-coupling reactions, which are essential for the construction of complex molecular architectures.

Beyond pharmaceutical applications, 1-Bromo-2-ethyl-4-methoxybenzene has also found utility in materials science. Researchers have utilized this compound as a building block for the synthesis of advanced materials with tailored properties. A notable example is its use in the preparation of conductive polymers for electronic devices. The presence of the bromine atom allows for controlled polymerization reactions, leading to materials with improved electrical conductivity and mechanical stability. This has opened up new possibilities for applications in flexible electronics and energy storage devices.

In the context of chemical synthesis, 1-Bromo-2-ethyl-4-methoxybenzene serves as a valuable starting material for a wide range of organic transformations. Its reactivity profile makes it an ideal candidate for Suzuki-Miyaura coupling reactions, which are widely used in the synthesis of biologically active compounds and fine chemicals. A recent study published in Organic Letters demonstrated the efficient synthesis of substituted biphenyls using 1-Bromo-2-ethyl-4-methoxybenzene as a key intermediate, highlighting its versatility and reliability in complex synthetic schemes.

The environmental impact and safety profile of 1-Bromo-2-ethyl-4-methoxybenzene are also important considerations. While it is generally considered safe for laboratory use when proper handling protocols are followed, it is essential to adhere to standard safety guidelines to minimize potential risks. Studies have shown that this compound does not pose significant environmental hazards when used responsibly and disposed of according to regulatory requirements.

In conclusion, 1-Bromo-2-ethyl-4-methoxybenzene (CAS No. 34881-44-2) is a multifaceted compound with a wide range of applications in pharmaceuticals, materials science, and chemical synthesis. Its unique chemical structure and reactivity make it an invaluable tool for researchers and chemists working on innovative projects. As ongoing research continues to uncover new possibilities, the importance of this compound is likely to grow further in the coming years.

• 565183-41-7(BENZENE, 2-BROMO-1,3-BIS(1,1-DIMETHYLETHYL)-5-METHOXY-)
• 68355-78-2(1-bromo-2-[(4-methoxyphenyl)methyl]-Benzene)
• 852946-96-4(2-bromo-1-ethyl-4-methoxyBenzene)
• 99873-30-0(4-Bromo-3-ethylphenol)
• 141548-58-5(Benzene, 2-bromo-4-methoxy-1-[2-(4-methoxyphenyl)ethyl]-)
• 75534-35-9(2-(2-bromo-5-methoxy-phenyl)ethanol)
• 27387-23-1(2-(2-Bromo-5-methoxyphenyl)acetonitrile)
• 34881-45-3(4-Bromo-3-isopropylanisole)
• 565183-43-9(1,3-BENZENEDIACETONITRILE, 2-BROMO-5-METHOXY-)
• 198630-95-4(Benzene, 1-bromo-2-(2-bromoethyl)-4-methoxy-)