Cas no 3483-12-3 (DL-dithiothreitol)

DL-dithiothreitol is a reducing agent that effectively cleaves disulfide bonds in proteins, allowing for the reduction and unfolding of complex molecular structures. Its high specificity and efficiency facilitate detailed structural analysis and purification of sensitive biomolecules, making it an essential tool in protein biochemistry research.
DL-dithiothreitol structure
DL-dithiothreitol structure
Product Name:DL-dithiothreitol
CAS No:3483-12-3
MF:C4H10O2S2
MW:154.250998973846
MDL:MFCD00004877
CID:44209
PubChem ID:329798930
Update Time:2026-05-14

DL-dithiothreitol Chemical and Physical Properties

Names and Identifiers

    • L-DTT
    • D-threo-1,4-Dimercapto-2,3-butanediol
    • 2,3-Butanediol, 1,4-dimercapto-, D-threo-
    • Cleland reagent
    • 1,4-Dithiothreitol
    • D-1,4-Dithiothreitol
    • D-Dtt
    • Sputolysin
    • Threitol, 1,4-dithio-
    • (R*,R*)-1,4-Dimercapto-2,3-butanediol
    • 1,4-Dithio-l-threitol
    • Cleland's reagent
    • Cleland regent
    • Clelands reagent
    • DL-1,4-Dithiothreitol
    • DL-Dithiothreitol (DTT)
    • DL-Dithiothreitol [for Electrophoresis]
    • 1,4-Dithio-DL-threitol
    • DITHIOTHREITOL
    • DL-Dithiothreitol
    • DTT
    • rac Dithiothreitol
    • DTT (DL-DITHIOTHREITOL)
    • (R,R)-Dithiothreitol
    • 2,3-Butanediol, 1,4-dimercapto-, (R*,R*)-
    • Cleland’s reagent
    • DL-1,4-Dithiothreitol, for Molecular biology, 1M solution in water
    • threo-1,4-Dimercapto-2,3-butanediol
    • cleland′s reagent
    • dithiothreitol, 1,4-
    • DL-2,3-Dihydroxy-1,4-butanedithiol
    • DL-1,4-Dimercapto-2,3-butanediol
    • DL-DTT
    • Threitol, 1,4-dithio- (7CI,8CI)
    • DL-1,4-Dimercapto-2,3-dihydroxybutane
    • DTT (threitol derivative)
    • Reagents, Cleland's
    • WR 34678
    • rac-Dithiothreitol
    • threo-2,3-Dihydroxy-1,4-butanedithiol
    • threo-2,3-Dihydroxy-1,4-dithiolbutane
    • 2,3-Butanediol,1,4-dimercapto-, (2R,3R)-rel-
    • (R,R)-Dithiothreitol; 2,3-Butanediol, 1,4-dimercapto-, (R*,R*)-; Dithiothreitol; DTT;
    • 2,3-Butanediol,1,4-dimercapto-, (R*,R*)-
    • Dithiotreitol
    • 1,4-Dimercaptobutane-2,3-diol
    • 1,4-Dithioerythritol
    • 1,4-disulfanylbutane-2,3-diol
    • 2,3-Butanediol, 1,4-dimercapto-
    • 1,4-dimercapto-2,3-butanediol
    • Threitol, 1,4-dithio-, DL-
    • Cleland's Reagent;DTE
    • L-1,4-Dithiothreitol
    • L-Dithiothreitol
    • 1,4-Bissulf
    • 1,4-Dithiothreitol (DTT)
    • RNase-free DTT Solution
    • DL-dithiothreitol
    • MDL: MFCD00004877
    • Inchi: 1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2
    • InChI Key: VHJLVAABSRFDPM-UHFFFAOYSA-N
    • SMILES: S([H])C([H])([H])C([H])(C([H])(C([H])([H])S[H])O[H])O[H]
    • BRN: 1719757

Computed Properties

  • Exact Mass: 154.01200
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 4
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 8
  • Rotatable Bond Count: 3
  • Complexity: 52
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 2
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • XLogP3: -0.4
  • Topological Polar Surface Area: 42.5

Experimental Properties

  • Color/Form: White powder
  • Density: 1.04?g/mL?at 20?°C
    1.035?g/mL?at 25?°C
  • Melting Point: 41-44?°C (lit.)
  • Boiling Point: 130°C/2mmHg(lit.)
  • Flash Point: Degrees Fahrenheit:235.4°F
    Degrees Celsius:113°C
  • Refractive Index: 1.5200 (estimate)
  • PH: 4.0-6.0 (20-25℃, 0.1m in H2O)
  • Solubility: H2O: 50?mg/mL, clear, colorless
  • Water Partition Coefficient: Soluble
  • Stability/Shelf Life: Stability Stable, but heat sensitive. Incompatible with strong oxidizing agents. Keep frozen at -20 to -10 C.
  • PSA: 118.06000
  • LogP: -0.43220
  • Merck: 3376
  • Sensitiveness: Air Sensitive
  • Color/Form: 1?M in H2O
  • Solubility: Not determined

DL-dithiothreitol Security Information

  • Symbol: GHS07
  • Prompt:warning
  • Signal Word:Warning
  • Hazard Statement: H302,H315,H319,H335
  • Warning Statement: P261,P305+P351+P338
  • Hazardous Material transportation number:NONH for all modes of transport
  • WGK Germany:3
  • Hazard Category Code: 22-36/37/38
  • Safety Instruction: S26-S37/39
  • FLUKA BRAND F CODES:3-10-16-23
  • RTECS:EK1610000
  • Hazardous Material Identification: Xn
  • TSCA:Yes
  • Storage Condition:2-8°C
  • Risk Phrases:R22; R36/37/38

DL-dithiothreitol Customs Data

  • HS CODE:2930909090
  • Customs Data:

    China Customs Code:

    2930909090

    Overview:

    2930909090. Other organic sulfur compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

DL-dithiothreitol Pricemore >>

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DL-dithiothreitol Suppliers

Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:3483-12-3)DL-Dithiothreitol
Order Number:sfd14408
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:36
Price ($):discuss personally
Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:3483-12-3)DL-dithiothreitol
Order Number:A822424
Stock Status:in Stock
Quantity:500g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 05:15
Price ($):571.0
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:3483-12-3)1,4-Dithio-DL-threitol
Order Number:LE3121;LE18824
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 11:43
Price ($):discuss personally

DL-dithiothreitol Spectrogram

1H NMR 300 MHz DMSO
1H NMR
13C NMR
13C NMR
Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:3483-12-3)DL-Dithiothreitol
sfd14408
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email
Amadis Chemical Company Limited
(CAS:3483-12-3)DL-dithiothreitol
A822424
Purity:99%
Quantity:500g
Price ($):571.0
Email