• 1. Evidence of rutile-to-anatase photo-induced electron transfer in mixed-phase TiO2 by solid-state NMR spectroscopy?
  Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
• 2. Empowering microfluidics by micro-3D printing and solution-based mineral coating?
  Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
• 3. Fast-pulsing NMR techniques for the detection of weak interactions: successful natural abundance probe of hydrogen bonds in peptides?
  Amandine Altmayer-Henzien,Valérie Declerck,David J. Aitken,Ewen Lescop,Denis Merlet,Jonathan Farjon Org. Biomol. Chem., 2013,11, 7611-7615
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Phenylmethylamines

4-(Aminomethyl)benzyldimethylamine Dihydrochloride: A Comprehensive Overview

The compound 4-(Aminomethyl)benzyldimethylamine Dihydrochloride (CAS No. 34490-85-2) is a significant chemical entity with diverse applications in various fields, including pharmaceuticals, agrochemicals, and materials science. This compound is characterized by its unique structure, which combines an aminomethyl group attached to a benzyl ring and two methylamine groups, forming a dihydrochloride salt. Its chemical formula is C10H16N2·2HCl, and it exhibits a molecular weight of 217.68 g/mol.

Recent studies have highlighted the potential of 4-(Aminomethyl)benzyldimethylamine Dihydrochloride in drug delivery systems due to its ability to act as a pH-responsive carrier. Researchers have demonstrated that this compound can encapsulate hydrophobic drugs and release them in a controlled manner under specific pH conditions, making it a promising candidate for targeted drug delivery applications. This property is attributed to the compound's ability to form stable micellar structures in aqueous solutions, which can encapsulate drug molecules and protect them from premature degradation.

In addition to its role in drug delivery, 4-(Aminomethyl)benzyldimethylamine Dihydrochloride has been explored for its potential in the synthesis of advanced materials. For instance, recent advancements in polymer chemistry have utilized this compound as a building block for the creation of stimuli-responsive polymers. These polymers exhibit reversible changes in their physical properties in response to external stimuli such as temperature or pH, opening new avenues for applications in sensors, actuators, and smart textiles.

The synthesis of 4-(Aminomethyl)benzyldimethylamine Dihydrochloride typically involves multi-step reactions, including alkylation and quaternization processes. Recent optimizations in synthetic protocols have focused on improving yield and purity while reducing environmental impact. For example, researchers have developed eco-friendly methods using microwave-assisted synthesis or catalytic systems that minimize the use of hazardous solvents and reagents.

From an analytical standpoint, the characterization of 4-(Aminomethyl)benzyldimethylamine Dihydrochloride has been enhanced by advanced spectroscopic techniques such as NMR and mass spectrometry. These methods provide detailed insights into the compound's molecular structure and stability under various conditions. Furthermore, computational chemistry approaches have been employed to predict the compound's behavior in different chemical environments, aiding in the design of more efficient synthetic pathways and applications.

Looking ahead, the demand for 4-(Aminomethyl)benzyldimethylamine Dihydrochloride is expected to grow due to its versatility across multiple industries. Its role as an intermediate in pharmaceutical synthesis, combined with its potential in advanced materials science, positions it as a key compound for future innovations. As research continues to uncover new applications and optimize existing ones, this compound will likely play an increasingly important role in both academic and industrial settings.

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• 4788-37-8(N-Ethyl-N-methylbenzylamine)
• 1875-92-9(Benzenemethanamine,N,N-dimethyl-, hydrochloride (1:1))
• 14800-26-1(Benzenemethanaminium,N,N-dimethyl-N-(phenylmethyl)-)
• 102-05-6(Dibemethine)
• 14800-24-9(Benzenemethanaminium,N,N,N-trimethyl-)
• 16846-81-4(1,4-Benzenedimethanaminium,N1,N1,N1,N4,N4,N4-hexamethyl-, bromide (1:2))
• 56-93-9(Benzyltrimethylammonium chloride)
• 111865-47-5(Benzyl trimethyl ammonium tribromide)