Cas no 34451-66-6 (2-ethyl-2-hydroxybutanenitrile)

2-Ethyl-2-hydroxybutanenitrile is a nitrile compound featuring both hydroxyl and ethyl functional groups, making it a versatile intermediate in organic synthesis. Its structure allows for applications in the production of pharmaceuticals, agrochemicals, and specialty chemicals, where selective functionalization is required. The presence of the hydroxyl group enhances reactivity in condensation and substitution reactions, while the nitrile group offers opportunities for further derivatization, such as hydrolysis to carboxylic acids or reduction to amines. This compound is particularly useful in fine chemical synthesis due to its balanced reactivity and stability under controlled conditions. Proper handling and storage are essential to maintain its integrity.

2-ethyl-2-hydroxybutanenitrile structure

34451-66-6 structure

Product Name:2-ethyl-2-hydroxybutanenitrile

CAS No:34451-66-6

MF:C₆H₁₁NO

MW:113.157641649246

MDL:MFCD01737428

CID:1468754

PubChem ID:36832

Update Time:2025-06-08

2-ethyl-2-hydroxybutanenitrile Chemical and Physical Properties

Names and Identifiers

- 2-ethyl-2-hydroxybutyronitrile
- Butyronitrile, 2-ethyl-2-hydroxy-
- 3-Pentanone cyanohydrin
- BRN 1700508
- USAF A-17195
- 2-ethyl-2-hydroxybutanenitrile
- NS00029667
- ALBB-032359
- EN300-85615
- 2-hydroxy-2-ethylbutanenitrile
- 4-03-00-00855 (Beilstein Handbook Reference)
- A822244
- F8889-6324
- 34451-66-6
- EINECS 252-037-9
- AKOS009470620
- SCHEMBL1169619
- DTXSID10188025
- 2-ethyl-2-oxidanyl-butanenitrile
- 2-ethyl-2-hydroxy-butyronitrile
- Butanenitrile, 2-ethyl-2-hydroxy-
- LS-11980
- CS-0263221
- Q2Q4G4LA34
- MDL： MFCD01737428
- Inchi： 1S/C6H11NO/c1-3-6(8,4-2)5-7/h8H,3-4H2,1-2H3
- InChI Key： QWJRZIUNOYNJIQ-UHFFFAOYSA-N
- SMILES： OC(C#N)(CC)CC

Computed Properties

Exact Mass: 113.08413
Monoisotopic Mass: 113.084
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Heavy Atom Count: 8
Rotatable Bond Count: 2
Complexity: 107
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Topological Polar Surface Area: 44A^2
XLogP3: 1

Experimental Properties

Density: 0.954
Boiling Point: 214.4°C at 760 mmHg
Flash Point: 83.5°C
Refractive Index: 1.44
PSA: 44.02
LogP: 1.06108

2-ethyl-2-hydroxybutanenitrile Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
TRC	B439528-10mg	2-ethyl-2-hydroxybutanenitrile	34451-66-6		10mg	$ 50.00	2022-06-07
TRC	B439528-50mg	2-ethyl-2-hydroxybutanenitrile	34451-66-6		50mg	$ 160.00	2022-06-07
TRC	B439528-100mg	2-ethyl-2-hydroxybutanenitrile	34451-66-6		100mg	$ 250.00	2022-06-07
eNovation Chemicals LLC	Y1249429-1g	2-ethyl-2-hydroxybutyronitrile	34451-66-6	tech grade	1g	$1125	2024-06-06
Enamine	EN300-85615-0.05g	2-ethyl-2-hydroxybutanenitrile	34451-66-6	95.0%	0.05g	$135.0	2025-03-21
Enamine	EN300-85615-0.1g	2-ethyl-2-hydroxybutanenitrile	34451-66-6	95.0%	0.1g	$202.0	2025-03-21
Enamine	EN300-85615-0.25g	2-ethyl-2-hydroxybutanenitrile	34451-66-6	95.0%	0.25g	$289.0	2025-03-21
Enamine	EN300-85615-0.5g	2-ethyl-2-hydroxybutanenitrile	34451-66-6	95.0%	0.5g	$480.0	2025-03-21
Enamine	EN300-85615-1.0g	2-ethyl-2-hydroxybutanenitrile	34451-66-6	95.0%	1.0g	$614.0	2025-03-21
Enamine	EN300-85615-2.5g	2-ethyl-2-hydroxybutanenitrile	34451-66-6	95.0%	2.5g	$1202.0	2025-03-21

2-ethyl-2-hydroxybutanenitrile Suppliers

Amadis Chemical Company Limited

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(CAS:34451-66-6)2-ethyl-2-hydroxybutanenitrile

Order Number:A822244

Stock Status:in Stock

Quantity:1g

Purity:99%

Pricing Information Last Updated:Monday, 2 September 2024 16:09

Price ($):1076.0

Email:[email protected]

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Additional information on 2-ethyl-2-hydroxybutanenitrile

Introduction to 2-Ethyl-2-Hydroxybutanenitrile (CAS No 34451-66-6)

2-Ethyl-2-hydroxybutanenitrile, also known by its CAS registry number CAS No 34451-66-6, is a versatile organic compound with the molecular formula C?H??NO? and a molecular weight of 137.17 g/mol. This compound is a nitrile derivative with a hydroxyl group, making it a valuable intermediate in various chemical synthesis processes. Its structure consists of a four-carbon chain with a hydroxyl group and a nitrile group attached to the second carbon, along with an ethyl substituent on the same carbon, giving it the name 2-ethyl. This unique structure allows for a wide range of applications in different industries.

The synthesis of 2-ethyl-2-hydroxybutanenitrile typically involves multi-step reactions, often starting from simpler precursors such as alcohols or ketones, followed by nitrile formation through various methods like the Stephen reduction or other nitrile synthesis techniques. The compound's ability to undergo further functional group transformations makes it highly valuable in organic synthesis, particularly in the pharmaceutical and agrochemical industries.

In recent years, researchers have explored the use of 2-ethyl-2-hydroxybutanenitrile in the development of bioactive compounds. Studies have shown that this compound can serve as a building block for creating molecules with potential pharmacological activities, such as anti-inflammatory or antimicrobial properties. For instance, a study published in the Journal of Medicinal Chemistry highlighted its role in synthesizing derivatives that exhibit significant activity against certain bacterial strains.

Beyond its role in drug discovery, CAS No 34451-66-6 has also found applications in the field of polymer chemistry. Its nitrile group can be polymerized under specific conditions to form materials with unique mechanical properties, making it a candidate for advanced materials development. Recent advancements in polymerization techniques have further expanded its potential uses in this area.

The chemical stability and reactivity of 2-ethyl-2-hydroxybutanenitrile make it an ideal candidate for various industrial processes. Its ability to participate in both nucleophilic and electrophilic reactions allows for its integration into diverse chemical pathways, enhancing its utility across multiple sectors.

In conclusion, 2-Ethyl-2-Hydroxybutanenitrile (CAS No 34451-66-6) is a multifaceted compound with significant potential in contemporary chemical research and industrial applications. Its structural versatility and reactivity continue to drive innovation across various fields, making it an essential component in modern organic synthesis.

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