Cas no 34450-16-3 (N1-Acetylspermidine Dihydrochloride)

N1-Acetylspermidine Dihydrochloride is a chemically modified derivative of spermidine, featuring acetylation at the N1 position and formulated as a dihydrochloride salt for enhanced stability and solubility. This compound is widely utilized in biochemical and pharmacological research due to its role in polyamine metabolism and cellular processes such as autophagy, proliferation, and differentiation. The dihydrochloride form ensures improved handling and storage characteristics, making it suitable for experimental applications requiring precise dosing. Its acetylated structure may influence bioavailability and metabolic pathways, offering insights into polyamine-related mechanisms. The product is typically characterized by high purity, ensuring reliability in research settings.
N1-Acetylspermidine Dihydrochloride structure
34450-16-3 structure
Product Name:N1-Acetylspermidine Dihydrochloride
CAS No:34450-16-3
MF:C9H23Cl2N3O
MW:260.20442032814
MDL:MFCD00058261
CID:919196
PubChem ID:214848
Update Time:2025-05-19

N1-Acetylspermidine Dihydrochloride Chemical and Physical Properties

Names and Identifiers

    • N(sup 1)-acetylspermidine dihydrochloride
    • N1-Acetylspermidine Dihydrochloride
    • N1-Acetylspermidine (hydrochloride)
    • N1-Acetylspermidine hydrochloride
    • SCHEMBL7517784
    • Acetamide, N-(3-((4-aminobutyl)amino)propyl)-, dihydrochloride
    • N(sup 1)-Acetylspermidine hydrochloride
    • n1-acetylspermidine 2hcl
    • N8-ACETYLSPERMIDINEDIHYDROCHLORIDE
    • N-[3-(4-aminobutylamino)propyl]acetamide dihydrochloride
    • N-[4-(3-aminopropylamino)butyl]acetamide,dihydrochloride
    • N-[3-[(4-Aminobutyl)amino]propyl]acetamide Hydrochloride (1:2)
    • N(sup 1)-Monoacetylspermidine dihydrochloride
    • HY-113056A
    • N-(3-(4-aminobutylamino)propyl)acetamide dihydrochloride
    • AKOS027322130
    • N-(3-((4-Aminobutyl)amino)propyl)acetamide diHCl
    • DB-244115
    • N-(3-((4-Aminobutyl)amino)propyl)acetamide dihydrochloride
    • MFCD00058261
    • CS-0108246
    • N-(3-((4-Aminobutyl)amino)propyl)acetamide 2HCl
    • BS-16922
    • N-[3-(4-aminobutylamino)propyl]acetamide;dihydrochloride
    • Acetamide, N-[3-[(4-aminobutyl)amino]propyl]-, dihydrochloride
    • 34450-16-3
    • MDL: MFCD00058261
    • Inchi: 1S/C9H21N3O.2ClH/c1-9(13)12-8-4-7-11-6-3-2-5-10;;/h11H,2-8,10H2,1H3,(H,12,13);2*1H
    • InChI Key: IVLOLMVLUOGVCZ-UHFFFAOYSA-N
    • SMILES: Cl.Cl.O=C(C)NCCCNCCCCN

Computed Properties

  • Exact Mass: 259.12209
  • Monoisotopic Mass: 187.168462
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 9
  • Complexity: 128
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 67.2

Experimental Properties

  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 380.5°C at 760 mmHg
  • Flash Point: 183.9°C
  • PSA: 67.15
  • Vapor Pressure: 0.0±0.8 mmHg at 25°C

N1-Acetylspermidine Dihydrochloride Security Information

N1-Acetylspermidine Dihydrochloride Pricemore >>

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$ 110.00 2023-09-09
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abcr
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N-(3-((4-Aminobutyl)amino)propyl)acetamide dihydrochloride, 95%; .
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SHANG HAI XIAN DING Biotechnology Co., Ltd.
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N1-Acetylspermidine Dihydrochloride Related Literature

Additional information on N1-Acetylspermidine Dihydrochloride

N1-Acetylspermidine Dihydrochloride (CAS No. 34450-16-3): A Comprehensive Guide to Its Properties and Applications

N1-Acetylspermidine Dihydrochloride (CAS No. 34450-16-3) is a chemically modified derivative of spermidine, a naturally occurring polyamine involved in critical cellular processes. This compound has garnered significant attention in biochemical and pharmacological research due to its unique properties and potential therapeutic applications. Researchers and pharmaceutical companies are increasingly interested in N1-Acetylspermidine Dihydrochloride for its role in modulating cellular metabolism and its implications in aging, autophagy, and neurodegenerative diseases.

The molecular structure of N1-Acetylspermidine Dihydrochloride includes an acetyl group attached to the N1 position of spermidine, enhancing its stability and bioavailability. This modification makes it a valuable tool in studying polyamine-related pathways. With the growing interest in longevity and anti-aging research, compounds like N1-Acetylspermidine Dihydrochloride are being explored for their potential to activate autophagy, a cellular recycling process linked to lifespan extension.

One of the most searched questions in scientific forums is: "What is the role of N1-Acetylspermidine Dihydrochloride in cellular health?" Studies suggest that this compound may influence gene expression, protein synthesis, and cell proliferation, making it a subject of interest in cancer research and regenerative medicine. Additionally, its dihydrochloride salt form ensures better solubility in aqueous solutions, facilitating laboratory and clinical applications.

In the context of neurodegenerative diseases, N1-Acetylspermidine Dihydrochloride has shown promise in preclinical studies. Researchers are investigating its ability to cross the blood-brain barrier and modulate polyamine levels, which are often dysregulated in conditions like Alzheimer's and Parkinson's disease. The compound's potential to enhance cognitive function and neuronal repair aligns with the current focus on brain health supplements and neuroprotective agents.

From a commercial perspective, the demand for N1-Acetylspermidine Dihydrochloride is rising due to its applications in cosmeceuticals and nutraceuticals. Skincare brands are exploring its anti-aging properties, while supplement manufacturers are incorporating it into formulations aimed at promoting cellular rejuvenation. This trend reflects the broader market shift towards bioactive compounds with scientifically backed benefits.

For laboratory use, N1-Acetylspermidine Dihydrochloride is available in high-purity grades, ensuring reproducibility in experiments. Its stability under standard storage conditions (room temperature, dry environment) makes it a convenient reagent for researchers. Common queries like "How to dissolve N1-Acetylspermidine Dihydrochloride?" are addressed by its high solubility in water and buffers, simplifying experimental protocols.

In summary, N1-Acetylspermidine Dihydrochloride (CAS No. 34450-16-3) is a versatile compound with broad applications in biochemistry, medicine, and consumer health. Its role in autophagy, neuroprotection, and anti-aging research positions it at the forefront of scientific innovation. As interest in longevity science and personalized medicine grows, this compound is likely to remain a key focus for researchers and industry professionals alike.

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