• 1. Diels–Alder reactions between maleic anhydride and furan derivatives in supercritical CO2
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• 2. Chapter 18. Alicyclic chemistry
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acid esters
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Benzoic acid esters

Professional Introduction to 2-Furanmethanol,2-benzoate (CAS No. 34171-46-5)

2-Furanmethanol,2-benzoate, with the chemical formula C₁₀H₈O₃, is a significant compound in the realm of organic chemistry and pharmaceutical research. Its CAS number, 34171-46-5, identifies it as a distinct molecular entity with unique structural and functional properties. This compound has garnered attention due to its versatile applications in synthetic chemistry, drug development, and material science.

The structure of 2-Furanmethanol,2-benzoate consists of a furan ring substituted with a hydroxymethyl group and a benzoate moiety. This dual functionality makes it a valuable intermediate in the synthesis of more complex molecules. The furan ring, characterized by its oxygen-containing heterocycle, contributes to the compound's reactivity and potential biological activity. Meanwhile, the benzoate group introduces additional electronic and steric effects that can be exploited in medicinal chemistry.

In recent years, 2-Furanmethanol,2-benzoate has been extensively studied for its role in the development of novel therapeutic agents. Its derivatives have shown promise in various pharmacological applications, including anti-inflammatory, antimicrobial, and anticancer properties. The compound's ability to undergo diverse chemical transformations makes it an attractive scaffold for drug design. Researchers have leveraged its structural features to develop molecules with enhanced binding affinity and improved pharmacokinetic profiles.

One of the most compelling aspects of 2-Furanmethanol,2-benzoate is its utility in the synthesis of bioactive molecules. For instance, studies have demonstrated its use in creating furan-based analogs that exhibit potent inhibitory effects on specific enzymatic targets. These targets are often implicated in metabolic disorders and chronic diseases, making such compounds valuable candidates for further development. The benzoate moiety further enhances these properties by modulating solubility and metabolic stability.

The pharmaceutical industry has been particularly interested in 2-Furanmethanol,2-benzoate due to its potential as a precursor for active pharmaceutical ingredients (APIs). Researchers have explored its incorporation into various drug candidates, demonstrating its versatility in medicinal chemistry. For example, derivatives of this compound have been investigated for their ability to modulate neurotransmitter receptors, offering insights into potential treatments for neurological disorders.

Beyond pharmaceutical applications, 2-Furanmethanol,2-benzoate has found utility in other scientific domains. In materials science, its structural characteristics make it a candidate for developing functional polymers and coatings. These materials can exhibit unique properties such as enhanced durability or biodegradability, depending on the specific modifications applied.

The synthesis of 2-Furanmethanol,2-benzoate typically involves multi-step organic reactions that highlight modern synthetic methodologies. Advanced techniques such as catalytic hydrogenation and palladium-catalyzed cross-coupling reactions are often employed to construct the desired molecular framework efficiently. These synthetic approaches not only demonstrate the compound's synthetic accessibility but also showcase the latest advancements in organic chemistry.

Recent research has also focused on the computational modeling of 2-Furanmethanol,2-benzoate to predict its biological activity and optimize its pharmacological properties. Molecular docking studies have been particularly useful in identifying potential binding interactions with biological targets. These computational tools provide valuable insights into how structural modifications can enhance drug efficacy and reduce side effects.

The environmental impact of synthesizing and utilizing 2-Furanmethanol,2-benzoate is another area of growing interest. Sustainable chemistry principles are being applied to develop greener synthetic routes that minimize waste and reduce energy consumption. Such efforts align with global initiatives to promote environmentally responsible chemical manufacturing practices.

In conclusion, 2-Furanmethanol, 2-benzoate (CAS No. 34171-46-5) is a multifaceted compound with significant implications across multiple scientific disciplines. Its unique structural features make it a valuable intermediate in pharmaceutical research, while its derivatives offer promising leads for new therapeutics. Additionally, 2-Furanmethanol, 2-benzoate continues to be explored for applications in materials science and sustainable chemistry. As research progresses, this compound will likely remain at the forefront of scientific innovation.

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