Cas no 34171-43-2 ((2-Chloro-5-methylpyrimidin-4-yl)-dimethylamine)
(2-Chloro-5-methylpyrimidin-4-yl)-dimethylamine Chemical and Physical Properties
Names and Identifiers
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- 2-Chloro-N,N,5-trimethylpyrimidin-4-amine
- 2-Chlor-4-dimethylamino-5-methyl-pyrimidin
- 2-chloro-4-dimethylamino-5-methylpyrimidine
- 2-chloro-N,N,5-trimethylpyrimidin-4-amine(SALTDATA: FREE)
- 4-Pyrimidinamine,2-chloro-N,N,5-trimethyl
- DTXSID50187774
- CS-0359190
- Pyrimidine, 2-chloro-4-(dimethylamino)-5-methyl-
- DA-18580
- BS-36754
- BRN 0608293
- SCHEMBL4265514
- 5-Methyl-4-dimethylamino-2-chloropyrimidine
- AKOS006282984
- (2-Chloro-5-methyl-pyrimidin-4-yl)-dimethyl-amine
- MFCD01689696
- 2-chloro-4-dimethylamino-5-methyl pyrimidine
- CHEMBRDG-BB 4016714
- 2-Chloro-N,N,5-trimethyl-4-pyrimidinamine
- SB55596
- 2-chloro-N,N,5-trimethyl-pyrimidin-4-amine
- 2-Chloro-N,N,5-trimethylpyrimidin-4-amine, AldrichCPR
- 34171-43-2
- 4-Pyrimidinamine, 2-chloro-N,N,5-trimethyl-
- AM100684
- OMPXZZNLSYCISQ-UHFFFAOYSA-N
- 5-25-10-00196 (Beilstein Handbook Reference)
- G82812
- (2-Chloro-5-methylpyrimidin-4-yl)-dimethylamine
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- MDL： MFCD01689696
- Inchi： 1S/C7H10ClN3/c1-5-4-9-7(8)10-6(5)11(2)3/h4H,1-3H3
- InChI Key： OMPXZZNLSYCISQ-UHFFFAOYSA-N
- SMILES： ClC1=NC=C(C)C(=N1)N(C)C
Computed Properties
- Exact Mass: 171.05600
- Monoisotopic Mass: 171.056
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 11
- Rotatable Bond Count: 1
- Complexity: 129
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 29A^2
- XLogP3: 2
Experimental Properties
- Density: 1.207
- Boiling Point: 286.8°C at 760 mmHg
- Flash Point: 127.2°C
- Refractive Index: 1.567
- PSA: 29.02000
- LogP: 1.50440
(2-Chloro-5-methylpyrimidin-4-yl)-dimethylamine Customs Data
- HS CODE：2933599090
- Customs Data：
China Customs Code:
2933599090Overview:
2933599090. Other compounds with pyrimidine ring in structure(Including other compounds with piperazine ring on the structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
(2-Chloro-5-methylpyrimidin-4-yl)-dimethylamine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Fluorochem | 085119-1g |
2-Chloro-5-methyl-pyrimidin-4-yl)-dimethyl-amine |
34171-43-2 | 95% | 1g |
￡88.00 | 2022-03-01 | |
| Fluorochem | 085119-5g |
2-Chloro-5-methyl-pyrimidin-4-yl)-dimethyl-amine |
34171-43-2 | 95% | 5g |
￡257.00 | 2022-03-01 | |
| Fluorochem | 085119-10g |
2-Chloro-5-methyl-pyrimidin-4-yl)-dimethyl-amine |
34171-43-2 | 95% | 10g |
￡400.00 | 2022-03-01 | |
| Fluorochem | 085119-25g |
2-Chloro-5-methyl-pyrimidin-4-yl)-dimethyl-amine |
34171-43-2 | 95% | 25g |
￡794.00 | 2022-03-01 | |
| TRC | C993763-250mg |
(2-Chloro-5-methylpyrimidin-4-yl)-dimethylamine |
34171-43-2 | 250mg |
$ 50.00 | 2022-06-06 | ||
| TRC | C993763-500mg |
(2-Chloro-5-methylpyrimidin-4-yl)-dimethylamine |
34171-43-2 | 500mg |
$ 70.00 | 2022-06-06 | ||
| TRC | C993763-2.5g |
(2-Chloro-5-methylpyrimidin-4-yl)-dimethylamine |
34171-43-2 | 2.5g |
$ 295.00 | 2022-06-06 | ||
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | CBR00335-1G |
2-Chloro-N,N,5-trimethylpyrimidin-4-amine |
34171-43-2 | 1g |
￥2797.55 | 2023-11-10 | ||
| Chemenu | CM165233-5g |
2-chloro-N,N,5-trimethylpyrimidin-4-amine |
34171-43-2 | 95% | 5g |
$606 | 2021-08-05 | |
| Chemenu | CM165233-1g |
2-chloro-N,N,5-trimethylpyrimidin-4-amine |
34171-43-2 | 95% | 1g |
$119 | 2023-02-17 |
(2-Chloro-5-methylpyrimidin-4-yl)-dimethylamine Related Literature
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Domenico Lombardo,Gianmarco Munaò,Pietro Calandra,Luigi Pasqua,Maria Teresa Caccamo Phys. Chem. Chem. Phys., 2019,21, 11983-11991
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Abdelaziz Houmam,Emad M. Hamed Chem. Commun., 2012,48, 11328-11330
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David White,Sean R. Stowell Biomater. Sci., 2017,5, 463-474
-
Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126
Additional information on (2-Chloro-5-methylpyrimidin-4-yl)-dimethylamine
Recent Advances in the Study of (2-Chloro-5-methylpyrimidin-4-yl)-dimethylamine (CAS: 34171-43-2) in Chemical Biology and Pharmaceutical Research
The compound (2-Chloro-5-methylpyrimidin-4-yl)-dimethylamine (CAS: 34171-43-2) has recently garnered significant attention in the field of chemical biology and pharmaceutical research due to its potential applications in drug discovery and development. This heterocyclic compound, characterized by its pyrimidine core and dimethylamine substituent, has been the subject of various studies aimed at exploring its biological activity, synthetic utility, and therapeutic potential. In this research brief, we summarize the latest findings related to this compound, focusing on its role as a key intermediate in medicinal chemistry and its emerging applications in targeted therapies.
Recent studies have highlighted the importance of (2-Chloro-5-methylpyrimidin-4-yl)-dimethylamine as a versatile building block in the synthesis of biologically active molecules. Its structural features make it particularly valuable for the development of kinase inhibitors, which are a major focus in oncology research. For instance, researchers have utilized this compound to synthesize novel derivatives that exhibit potent inhibitory activity against specific kinases involved in cancer cell proliferation. These findings underscore the compound's potential as a scaffold for designing next-generation anticancer agents.
In addition to its applications in oncology, (2-Chloro-5-methylpyrimidin-4-yl)-dimethylamine has shown promise in the development of antiviral and anti-inflammatory agents. A recent study published in the Journal of Medicinal Chemistry demonstrated that derivatives of this compound exhibit significant activity against viral proteases, suggesting its utility in addressing emerging viral infections. Furthermore, its anti-inflammatory properties have been explored in the context of autoimmune diseases, with preliminary results indicating its ability to modulate key inflammatory pathways.
The synthetic accessibility of (2-Chloro-5-methylpyrimidin-4-yl)-dimethylamine has also been a topic of recent investigation. Advances in green chemistry have led to the development of more efficient and environmentally friendly synthetic routes for this compound. Researchers have reported improved yields and reduced waste generation through the use of catalytic methods and solvent-free conditions. These innovations not only enhance the scalability of production but also align with the growing emphasis on sustainable practices in pharmaceutical manufacturing.
Looking ahead, the potential of (2-Chloro-5-methylpyrimidin-4-yl)-dimethylamine extends beyond its current applications. Ongoing research is exploring its use in the development of targeted drug delivery systems and as a probe for studying biological mechanisms at the molecular level. With its unique chemical properties and demonstrated biological activity, this compound is poised to play a pivotal role in advancing drug discovery efforts across multiple therapeutic areas. As such, continued investment in research and development is essential to fully realize its potential in addressing unmet medical needs.
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