• 1. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?
  Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198
• 2. Fatty acid positional distribution in colostrum and mature milk of women living in Inner Mongolia, North Jiangsu and Guangxi of China?
  Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245
• 3. Emerging investigator series: first-principles and thermodynamics comparison of compositionally-tuned delafossites: cation release from the (001) surface of complex metal oxides?
  Joseph W. Bennett,Diamond T. Jones,Blake G. Hudson,Joshua Melendez-Rivera,Robert J. Hamers,Sara E. Mason Environ. Sci.: Nano, 2020,7, 1642-1651
• 4. Establishing plasmon contribution to chemical reactions: alkoxyamines as a thermal probe?
  Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
• 5. Exchanged ligands on the surface of a giant cluster: [(MoO3)176(H2O)63(CH3OH)17Hn](32 – n)–
  Chem. Commun., 1998, 1501-1502

• Solvents and Organic Chemicals Organic Compounds Hydrocarbons

Comprehensive Analysis of 4-hydroxybenzene-1,3-dicarbonitrile (CAS No. 34133-58-9): Properties, Applications, and Industry Trends

4-hydroxybenzene-1,3-dicarbonitrile (CAS 34133-58-9), also known as 2,4-dicyanophenol, is a high-value aromatic nitrile derivative with a molecular formula of C₈H₄N₂O. This white to off-white crystalline powder has garnered significant attention in specialty chemical markets due to its unique electron-withdrawing cyano groups and hydroxyl functionality, making it a versatile intermediate for advanced material synthesis.

Recent Google Trends data reveals growing searches for "nitrile-based intermediates" and "high-performance polymer precursors", reflecting industry demand for compounds like 4-hydroxybenzene-1,3-dicarbonitrile. The compound's thermal stability (decomposition point >250°C) and solubility profile (soluble in polar aprotic solvents like DMF and DMSO) make it particularly valuable for researchers developing heat-resistant polymers and electronic materials.

In pharmaceutical applications, 34133-58-9 serves as a key building block for heterocyclic compound synthesis. Patent analysis shows its increasing use in developing bioactive molecules, particularly those targeting enzyme inhibition. The hydrogen bonding capability from its phenolic OH group combined with cyano group reactivity enables diverse molecular transformations, answering frequent search queries about "multifunctional pharmaceutical intermediates".

The material science sector utilizes 4-hydroxybenzene-1,3-dicarbonitrile in polyimide precursors and liquid crystal materials. Its incorporation into polymer backbones improves dielectric properties—a hot topic in 5G technology forums. Laboratory studies demonstrate that polymers derived from this compound exhibit exceptional dimensional stability under thermal stress, addressing industry needs for high-temperature adhesives and flexible circuit materials.

Environmental considerations have driven innovation in green synthesis routes for 34133-58-9. Recent publications highlight catalytic methods achieving >90% yields with reduced energy consumption, responding to searches for "sustainable nitrile chemistry". The compound's low bioaccumulation potential (log P ~1.2) and ready biodegradability in OECD tests make it an attractive alternative to halogenated intermediates.

Analytical characterization of 4-hydroxybenzene-1,3-dicarbonitrile typically involves HPLC purity analysis (typically >98%), FTIR spectroscopy (characteristic -CN stretch at 2230 cm^-1), and X-ray crystallography. These quality control aspects address common purchaser concerns about "nitrile compound specifications" and "material characterization methods".

Emerging applications include its use in organic semiconductor dopants and metal-organic frameworks (MOFs), particularly for gas storage materials. The compound's rigid planar structure and coordination sites enable construction of porous materials with tunable properties—a subject of numerous recent research papers and patent filings.

Market analysts project steady growth for aromatic dinitrile compounds like 34133-58-9, with CAGR of 5.2% through 2028. This aligns with increased demand for high-performance plastics in electric vehicles and advanced electronic encapsulation materials. Current technical literature emphasizes optimization of storage conditions (recommended desiccated at 2-8°C) and handling protocols to maintain product integrity.

Academic and industrial researchers frequently inquire about "scaling up 4-hydroxybenzene-1,3-dicarbonitrile production". Process chemistry studies suggest that continuous flow reactors can enhance yield and purity while reducing byproducts—an important consideration for cost-effective manufacturing of this specialty chemical.

In conclusion, 4-hydroxybenzene-1,3-dicarbonitrile (CAS 34133-58-9) represents a critical junction between traditional organic chemistry and cutting-edge material science. Its dual functionality continues to inspire innovations across multiple industries, from flexible electronics to targeted drug delivery systems, positioning it as a compound of enduring scientific and commercial importance.

• 69481-42-1(Benzonitrile, hydroxy-)
• 18495-14-2(2-Hydroxy-4-methylbenzonitrile)
• 4640-29-3(2,5-dihydroxybenzonitrile)
• 52449-77-1(2-Naphthalenecarbonitrile, 3-hydroxy-)
• 3816-66-8(3-Hydroxy-4-methylbenzonitrile)
• 64419-24-5(2,4-Dihydroxybenzonitrile)
• 57764-46-2(Benzonitrile,2,6-dihydroxy-)
• 611-20-1(2-Hydroxybenzonitrile)
• 4198-90-7(4-hydroxy-3,5-dimethylbenzonitrile)
• 52805-47-7(1-Naphthalenecarbonitrile, 2-hydroxy-)