Cas no 34052-90-9 (1,3-Bis(4,5-dihydrooxazol-2-yl)benzene)

1,3-Bis(4,5-dihydrooxazol-2-yl)benzene is a bifunctional oxazoline derivative featuring a benzene core symmetrically substituted with two oxazoline rings. This compound serves as a versatile ligand precursor in coordination chemistry and catalysis, particularly in asymmetric synthesis. Its rigid aromatic backbone enhances steric and electronic control, while the oxazoline moieties provide strong chelating ability to transition metals, such as palladium, copper, and nickel. The compound exhibits excellent stability under various reaction conditions and is widely employed in enantioselective transformations, including C-C bond-forming reactions and hydrogenations. Its modular structure allows for further functionalization, making it valuable in designing tailored catalytic systems for high-precision organic synthesis.
1,3-Bis(4,5-dihydrooxazol-2-yl)benzene structure
34052-90-9 structure
Product Name:1,3-Bis(4,5-dihydrooxazol-2-yl)benzene
CAS No:34052-90-9
MF:C12H12N2O2
MW:216.235882759094
MDL:MFCD00191606
CID:54181
PubChem ID:87564420
Update Time:2025-11-01

1,3-Bis(4,5-dihydrooxazol-2-yl)benzene Chemical and Physical Properties

Names and Identifiers

    • 1,3-Bis(4,5-dihydro-2-oxazolyl)benzene
    • 1,3-Phenylene-bis-oxazoline
    • 2,2'-(1,3-Phenylene)bis-2-oxazolin
    • 1,3-PBO
    • 1,3-PHENYLENBISOXAZOLINE
    • 2,2'-(1,3-Phenylene)bis(2-oxazoline)
    • 4,5,4',5'-tetrahydro-2,2'-m-phenylene-bis-oxazole
    • bisdihydrooxazolylbenzene
    • 1,3-Bis(4,5-dihydrooxazol-2-yl)benzene
    • Oxazole, 2,2'-(1,3-phenylene)bis[4,5-dihydro-
    • 2-[3-(4,5-Dihydro-1,3-oxazol-2-yl)phenyl]-4,5-dihydro-1,3-oxazole
    • 2,2'-(1,3-Phenylene)bis-2-oxazoline
    • CBDivE_014641
    • PubChem14603
    • 1,3-bis-(4,5-Dihydro-2-oxazolyl)benzene
    • 1,3-phenylenebis(2-oxazoline)
    • HMOZDINWBHMBSQ-UHFFFAOYSA-
    • HMOZDINWBHMBSQ-UHFFFAOYSA-N
    • AMY10792
    • AS-15426
    • 2,2'-(m-Phenylene)bis(2-oxazoline)
    • Oxazole, 2,2'-(1,3-phenylene)bis(4,5-dihydro-
    • NS00077701
    • L10055
    • MFCD00191606
    • AKOS024438239
    • SCHEMBL105809
    • InChI=1/C12H12N2O2/c1-2-9(11-13-4-6-15-11)8-10(3-1)12-14-5-7-16-12/h1-3,8H,4-7H2
    • 4,5-dihydro-2-(3-(4,5-dihydrooxazol-2-yl)phenyl)oxazole
    • 34052-90-9
    • FT-0606563
    • 2,2'-(1,3-phenylene)-bis(2-oxazoline)
    • SY039334
    • 2-[3-(4,5-Dihydro-1,3-oxazol-2-yl)phenyl]-4,5-dihydro-1,3-oxazole #
    • CS-0085575
    • DTXSID40885570
    • A822057
    • B1511
    • DB-020053
    • 1,3-Phenylene-bis-oxazoline; 2,2'-(1,3-Phenylene)bis-2-oxazolin
    • DTXCID801024936
    • MDL: MFCD00191606
    • Inchi: 1S/C12H12N2O2/c1-2-9(11-13-4-6-15-11)8-10(3-1)12-14-5-7-16-12/h1-3,8H,4-7H2
    • InChI Key: HMOZDINWBHMBSQ-UHFFFAOYSA-N
    • SMILES: O1CCN=C1C1C=CC=C(C=1)C1=NCCO1

Computed Properties

  • Exact Mass: 216.09000
  • Monoisotopic Mass: 216.089877630g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 2
  • Complexity: 295
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 1
  • Topological Polar Surface Area: 43.2

Experimental Properties

  • Color/Form: Powder
  • Density: 1.45
  • Melting Point: 146.0 to 149.0 deg-C
  • Boiling Point: 403.5°C at 760 mmHg
  • Flash Point: 208°C
  • PSA: 43.18000
  • LogP: 0.11140
  • Solubility: Not determined

1,3-Bis(4,5-dihydrooxazol-2-yl)benzene Security Information

1,3-Bis(4,5-dihydrooxazol-2-yl)benzene Customs Data

  • HS CODE:2934999090
  • Customs Data:

    China Customs Code:

    2934999090

    Overview:

    2934999090. Other heterocyclic compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1,3-Bis(4,5-dihydrooxazol-2-yl)benzene Pricemore >>

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1,3-Bis(4,5-dihydrooxazol-2-yl)benzene Production Method

1,3-Bis(4,5-dihydrooxazol-2-yl)benzene Suppliers

Suzhou Senfeida Chemical Co., Ltd
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(CAS:34052-90-9)1,3-Bis(4,5-dihydro-2-oxazolyl)benzene
Order Number:sfd7720
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:34
Price ($):discuss personally
Amadis Chemical Company Limited
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(CAS:34052-90-9)1,3-Bis(4,5-dihydrooxazol-2-yl)benzene
Order Number:A822057
Stock Status:in Stock
Quantity:500g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 05:15
Price ($):170.0

Additional information on 1,3-Bis(4,5-dihydrooxazol-2-yl)benzene

Comprehensive Overview of 1,3-Bis(4,5-dihydrooxazol-2-yl)benzene (CAS No. 34052-90-9)

1,3-Bis(4,5-dihydrooxazol-2-yl)benzene, identified by its CAS number 34052-90-9, is a specialized organic compound widely recognized for its unique structural properties and applications in advanced material science. This compound belongs to the class of bis-oxazoline derivatives, which are increasingly gaining attention due to their versatility in catalysis, polymer modification, and pharmaceutical intermediates. The presence of two oxazoline rings attached to a benzene core enhances its reactivity and binding capabilities, making it a valuable building block in synthetic chemistry.

In recent years, the demand for high-performance ligands and chiral auxiliaries has surged, driven by advancements in asymmetric synthesis and green chemistry. Researchers and industries are actively exploring compounds like 1,3-Bis(4,5-dihydrooxazol-2-yl)benzene for their ability to facilitate stereoselective reactions, a topic frequently searched in academic and industrial forums. Its role in metal-organic frameworks (MOFs) and coordination polymers has also been a focal point, aligning with the growing interest in sustainable materials and nanotechnology.

The compound's thermal stability and solubility profile make it suitable for diverse solvent systems, a feature often queried in chemical databases. Users frequently search for "solubility of bis-oxazoline derivatives" or "applications of CAS 34052-90-9," reflecting its relevance in both laboratory and industrial settings. Additionally, its potential in photoactive materials and catalysis has been highlighted in recent publications, addressing the need for eco-friendly alternatives in chemical manufacturing.

From a synthetic perspective, 1,3-Bis(4,5-dihydrooxazol-2-yl)benzene is often synthesized via cyclization reactions involving benzonitrile derivatives and amino alcohols. This process is a common subject in organic chemistry tutorials, with searches like "synthesis of bis-oxazoline ligands" trending among students and professionals. The compound's electron-rich nature further enables its use in cross-coupling reactions, a technique pivotal in drug discovery and material science.

In the context of polymer science, this compound serves as a chain extender or cross-linking agent, contributing to the mechanical strength and durability of engineered plastics. Queries such as "bis-oxazoline in polymer modification" underscore its industrial significance. Moreover, its compatibility with biodegradable polymers aligns with the global push toward sustainable packaging solutions, a hot topic in environmental science.

Safety and handling of CAS 34052-90-9 are also frequently discussed, with users seeking information on storage conditions and compatibility with other reagents. While not classified as hazardous, proper handling protocols are emphasized in technical datasheets, catering to the laboratory safety awareness trend. The compound's stability under ambient conditions is another advantage, reducing logistical challenges in procurement and storage.

In summary, 1,3-Bis(4,5-dihydrooxazol-2-yl)benzene (CAS No. 34052-90-9) is a multifaceted compound bridging gaps between academia and industry. Its applications in asymmetric synthesis, material science, and green chemistry resonate with current research priorities, making it a subject of continuous exploration and innovation.

Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:34052-90-9)1,3-Bis(4,5-dihydro-2-oxazolyl)benzene
sfd7720
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
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Amadis Chemical Company Limited
(CAS:34052-90-9)1,3-Bis(4,5-dihydrooxazol-2-yl)benzene
A822057
Purity:99%
Quantity:500g
Price ($):170.0
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