• 1. LXXVI.—The scission of diaryl ethers and related compounds by means of piperidine. Part II. The nitration of 2 : 4 : 4′-trichlorodiphenyl ether, and of 2 : 4-dichlorophenyl p-toluenesulphonate and benzoate
  Leslie George Groves,Eustace Ebenezer Turner,Gladys Irene Sharp J. Chem. Soc. 1929 512
• 2. Organic chemistry
  J. Chem. Soc. Abstr. 1909 96 A449

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Nitrobenzenes

Comprehensive Guide to Benzenamine,2,4-dichloro-5-nitro- (CAS No. 34033-44-8): Properties, Applications, and Market Insights

Benzenamine,2,4-dichloro-5-nitro- (CAS No. 34033-44-8) is a specialized nitro-substituted aromatic amine with significant industrial relevance. This compound, also known as 2,4-dichloro-5-nitroaniline, features a unique molecular structure combining chloro and nitro functional groups, making it valuable for synthetic chemistry applications. Its chemical formula C₆H₄Cl₂N₂O₂ and molecular weight of 207.01 g/mol position it as a key intermediate in organic synthesis.

The physicochemical properties of Benzenamine,2,4-dichloro-5-nitro- include a melting point range of 98-102°C and limited solubility in water but good solubility in organic solvents like ethanol and acetone. These characteristics make it particularly useful in dye manufacturing and pharmaceutical intermediates. Recent studies highlight its role in developing advanced materials, aligning with growing interest in sustainable chemistry solutions and green synthesis methods.

In industrial applications, CAS 34033-44-8 serves as a crucial building block for azo dyes and pigment production. The compound's nitro group enables important chemical transformations, while its chloro substituents provide stability to resulting molecules. This dual functionality answers frequent search queries about "versatile chemical intermediates" and "multi-functional aromatic compounds", topics trending in chemical research forums.

The global market for Benzenamine,2,4-dichloro-5-nitro- reflects steady growth, driven by demand from textile industries and specialty chemicals sectors. Manufacturers are increasingly focusing on high-purity grades to meet stringent quality requirements, particularly for electronic materials applications. This aligns with current industry searches for "high-performance chemical intermediates" and "specialty aromatic amines".

From a safety perspective, proper handling of 2,4-dichloro-5-nitroaniline requires standard laboratory precautions. While not classified as hazardous under normal conditions, its nitro aromatic nature warrants attention during storage and transportation. This information addresses common search terms like "chemical safety data" and "handling nitro compounds", which rank highly in chemical safety databases.

Research trends indicate growing interest in CAS 34033-44-8 for catalysis applications and material science innovations. The compound's unique electronic properties make it suitable for developing organic semiconductors, responding to searches about "conductive organic materials". Recent patents demonstrate its utility in creating advanced polymeric systems, a hot topic in materials science communities.

Environmental considerations for Benzenamine,2,4-dichloro-5-nitro- production emphasize waste minimization and energy-efficient processes. These aspects connect with popular searches about "green chemistry principles" and "sustainable chemical manufacturing". Industry leaders are adopting catalytic methods to improve the sustainability profile of this important intermediate.

Quality control for 34033-44-8 typically involves HPLC analysis and spectroscopic verification, addressing common quality-related queries. The compound's technical specifications often include purity ≥98% with controlled levels of isomeric impurities, important for researchers searching "analytical methods for nitroaromatics".

Future applications of 2,4-dichloro-5-nitroaniline may expand into agrochemical intermediates and electronic materials, according to recent market analyses. This projection responds to growing interest in "next-generation chemical intermediates" and aligns with investment trends in specialty chemicals. The compound's versatility continues to attract research attention across multiple disciplines.

For researchers and industry professionals, understanding the structure-activity relationship of Benzenamine,2,4-dichloro-5-nitro- remains crucial. Its molecular design offers valuable insights for developing novel compounds, addressing frequent searches about "rational chemical design" and "functional group effects" in organic synthesis.

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