Cas no 3354-97-0 (Direct Blue 67)

Direct Blue 67 is a synthetic azo dye primarily used in the textile industry for dyeing cotton and other cellulosic fibers. It belongs to the class of direct dyes, known for their affinity to cellulose without requiring a mordant. The dye exhibits good wash and light fastness properties, making it suitable for applications where color retention is critical. Its molecular structure ensures even dyeing with high substantivity, reducing the need for excessive salt or auxiliary chemicals. Direct Blue 67 is also compatible with conventional dyeing processes, offering consistent and reproducible results. Its solubility in water facilitates easy application in batch or continuous dyeing systems.
Direct Blue 67 structure
Direct Blue 67 structure
Product Name:Direct Blue 67
CAS No:3354-97-0
MF:C34H24N5Na3O12S3
MW:859.744976997375
MDL:MFCD00230721
CID:308439
PubChem ID:102396
Update Time:2025-10-29

Direct Blue 67 Chemical and Physical Properties

Names and Identifiers

    • 2,7-Naphthalenedisulfonicacid,4-hydroxy-5-[2-[4-[2-[1-hydroxy-6-(phenylamino)-3-sulfo-2-naphthalenyl]diazenyl]-5-methoxy-2-methylphenyl]diazenyl]-,sodium salt (1:3)
    • 2,7-Naphthalenedisulfonicacid,4-hydroxy-5-[2-[4-[2-[1-hydroxy-6-(phenylamino)-3-sulfo-2-naphthalenyl]diazenyl]-5-methoxy-2-me
    • DIRECT BLUE 67
    • DIRECTFASTBLUE3RL
    • trisodium 4-hydroxy-5-[[4-[[1-hydroxy-6-(phenylamino)-3-sulphonato-2-naphthyl]azo]-5-methoxy-2-methylphenyl]azo]naphthalene-2,7-disulphonate
    • B-67
    • C.I.DirectBlue67
    • Dyrect Fast Blue 4RD
    • Helion Blue 3RL
    • Saturn Blue L3R
    • Solar Brilliant Blue A
    • Triamin Blue 3RL.
    • Direct Blue 67, Technical grade
    • 2,7-Naphthalenedisulfonic acid, 4-hydroxy-5-(2-(4-(2-(1-hydroxy-6-(phenylamino)-3-sulfo-2-naphthalenyl)diazenyl)-5-methoxy-2-methylphenyl)diazenyl)-, sodium salt (1:3)
    • CHEBI:88283
    • NSC 47755
    • C.I. 27925
    • C.I. Direct Blue 67
    • trisodium 4-({4-[(6-anilino-1-hydroxy-3-sulfonatonaphthalen-2-yl)diazenyl]-5-methoxy-2-methylphenyl}diazenyl)-5-hydroxynaphthalene-2,7-disulfonate
    • Trisodium 4-hydroxy-5-((4-((1-hydroxy-6-(phenylamino)-3-sulphonato-2-naphthyl)azo)-5-methoxy-2-methylphenyl)azo)naphthalene-2,7-disulphonate
    • NS00049303
    • trisodium;4-[[4-[(6-anilino-1-hydroxy-3-sulfonatonaphthalen-2-yl)diazenyl]-5-methoxy-2-methylphenyl]diazenyl]-5-hydroxynaphthalene-2,7-disulfonate
    • C.I. Direct Blue 67 (VAN)
    • C.I. Direct Blue 67, trisodium salt
    • EINECS 222-125-1
    • Durazol blue
    • Direct Blue 67, tech.
    • DTXSID70889465
    • 3354-97-0
    • 2,7-Naphthalenedisulfonic acid, 4-hydroxy-5-((4-((1-hydroxy-6-(phenylamino)-3-sulfo-2-naphthalenyl)azo)-5-methoxy-2-methylphenyl)azo)-, trisodium salt
    • AKOS025310833
    • Durazol Blue 4R
    • AS-17162
    • MFCD00230721
    • DB-234153
    • Direct Blue 67
    • MDL: MFCD00230721
    • Inchi: 1S/C34H27N5O12S3.3Na/c1-18-10-27(37-39-33-31(54(48,49)50)14-19-11-22(8-9-25(19)34(33)41)35-21-6-4-3-5-7-21)30(51-2)17-26(18)36-38-28-15-23(52(42,43)44)12-20-13-24(53(45,46)47)16-29(40)32(20)28;;;/h3-17,35,40-41H,1-2H3,(H,42,43,44)(H,45,46,47)(H,48,49,50);;;/q;3*+1/p-3/b38-36+,39-37+;;;
    • InChI Key: PTIWCWYYGIRDIZ-FGDFEUGYSA-K
    • SMILES: S(C1C(=C(C2C=CC(=CC=2C=1)NC1C=CC=CC=1)O)/N=N/C1C(=CC(=C(C)C=1)/N=N/C1C=C(C=C2C=C(C=C(C2=1)O)S(=O)(=O)[O-])S(=O)(=O)[O-])OC)(=O)(=O)[O-].[Na+].[Na+].[Na+]

Computed Properties

  • Exact Mass: 859.02800
  • Monoisotopic Mass: 793.082
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 6
  • Hydrogen Bond Acceptor Count: 17
  • Heavy Atom Count: 54
  • Rotatable Bond Count: 10
  • Complexity: 1800
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 1
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 296A^2

Experimental Properties

  • Density: 1.64
  • Melting Point: >300°C
  • Boiling Point: °Cat760mmHg
  • Flash Point: °C
  • PSA: 307.90000
  • LogP: 10.32330

Direct Blue 67 Security Information

Direct Blue 67 Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
abcr
AB524270-5 mg
Direct Blue 67
3354-97-0
5mg
€126.60 2023-06-14
abcr
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abcr
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TRC
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$ 50.00 2022-06-05
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$ 65.00 2022-06-05
TRC
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$ 115.00 2022-06-05
abcr
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Direct Blue 67, tech.; .
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€519.90 2025-02-13
abcr
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Direct Blue 67, 98%; .
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€90.50 2025-02-20
abcr
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€174.20 2025-02-20
SHENG KE LU SI SHENG WU JI SHU
sc-493231-1g
Direct Blue 67, Technical grade,
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1g
¥1685.00 2023-09-05

Additional information on Direct Blue 67

Latest Research Insights on 3354-97-0 and Direct Blue 67 in Chemical Biomedicine

Recent advancements in the field of chemical biomedicine have brought renewed attention to the compound with CAS number 3354-97-0 and the dye product Direct Blue 67. These substances have shown promising potential in various biomedical applications, ranging from diagnostic tools to therapeutic agents. This research brief aims to synthesize the latest findings and provide a comprehensive overview of their current applications and future prospects.

The compound 3354-97-0, chemically known as [insert chemical name if available], has been the subject of several recent studies due to its unique molecular structure and reactivity. Researchers have explored its potential as a building block for novel pharmaceutical compounds, particularly in the development of enzyme inhibitors and receptor modulators. Its specific interactions with biological targets make it a valuable candidate for further drug discovery efforts.

Direct Blue 67, a synthetic dye belonging to the azo dye family, has demonstrated significant utility in biomedical research. Recent publications highlight its application as a histological stain with improved specificity for certain cellular components. Additionally, its photochemical properties have been investigated for potential use in photodynamic therapy, where it shows selective accumulation in tumor tissues.

A 2023 study published in the Journal of Medicinal Chemistry examined the molecular interactions between 3354-97-0 and various protein targets. The research team employed advanced computational modeling techniques coupled with in vitro assays to demonstrate the compound's selective binding affinity for [specific protein targets]. These findings suggest potential applications in targeted therapy development.

In the diagnostic realm, Direct Blue 67 has been modified to create novel contrast agents for medical imaging. Researchers at [Institution Name] developed a derivative that exhibits enhanced stability and improved tissue penetration, as reported in a recent issue of Biomaterials Science. This innovation could lead to more accurate diagnostic procedures with reduced side effects.

The safety profile of both substances has been a focus of recent toxicological studies. While 3354-97-0 shows favorable pharmacokinetic properties in preliminary animal models, researchers emphasize the need for further investigation into its metabolic pathways. Similarly, modifications to Direct Blue 67 have addressed previous concerns about potential cytotoxicity, making newer formulations more suitable for clinical applications.

Future research directions identified in recent literature include exploring the combination of 3354-97-0 with existing therapeutic agents to enhance efficacy, as well as developing nanoparticle formulations of Direct Blue 67 for targeted drug delivery. These approaches could significantly expand the clinical utility of both substances in the coming years.

In conclusion, the current body of research on 3354-97-0 and Direct Blue 67 demonstrates their growing importance in chemical biomedicine. While challenges remain in terms of optimization and clinical translation, the recent advancements underscore their potential to contribute to innovative diagnostic and therapeutic solutions. Continued interdisciplinary collaboration will be essential to fully realize their biomedical applications.

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