Cas no 33528-13-1 (N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide)

N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide is a nitroso sulfonamide derivative characterized by its stable yet reactive nitroso functional group, making it valuable in organic synthesis and nitrosation reactions. The compound's benzylic and methyl-substituted aromatic structure enhances its solubility in organic solvents, facilitating its use in controlled reaction conditions. Its well-defined molecular architecture ensures predictable reactivity, particularly in the formation of N-nitroso compounds. The sulfonamide moiety contributes to its stability under standard storage conditions, while the nitroso group remains accessible for selective transformations. This compound is particularly useful in research applications requiring precise nitrosation or as an intermediate in pharmaceutical and agrochemical synthesis.
N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide structure
33528-13-1 structure
Product Name:N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide
CAS No:33528-13-1
MF:C14H14N2O3S
MW:290.337562084198
MDL:MFCD00216617
CID:294296
PubChem ID:87560329
Update Time:2025-05-24

N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide Chemical and Physical Properties

Names and Identifiers

    • N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide
    • Benzenesulfonamide,4-methyl-N-nitroso-N-(phenylmethyl)-
    • N-BENZYL-N-NITROSO-P-TOLUENESULFONAMIDE
    • N-benzyl-N-nitroso-4-toluenesulfonamide
    • N-benzyl-N-nitroso-toluene-4-sulfonamide
    • N-Benzyl-N-nitroso-toluol-4-sulfonamid
    • N-benzyl-N-nitrosotosylamide
    • N-nitroso-N-benzyl-p-toluenesulphonamide
    • DTXSID60399508
    • N-Nitroso-N-benzyl-p-toluene sulphonamide
    • B3051
    • N-benzyl-4-methyl-N'-oxobenzenesulfonohydrazide
    • SCHEMBL3678710
    • AKOS015900659
    • CS-0035491
    • BS-41671
    • 33528-13-1
    • ZXELPGWSCCGNDS-UHFFFAOYSA-N
    • W12801
    • MFCD00216617
    • N-benzyl-N-nitroso-p-toluene-sulfonamide
    • MDL： MFCD00216617
    • Inchi： 1S/C14H14N2O3S/c1-12-7-9-14(10-8-12)20(18,19)16(15-17)11-13-5-3-2-4-6-13/h2-10H,11H2,1H3
    • InChI Key： ZXELPGWSCCGNDS-UHFFFAOYSA-N
    • SMILES： S(C1C=CC(C)=CC=1)(N(CC1C=CC=CC=1)N=O)(=O)=O

Computed Properties

  • Exact Mass: 290.07300
  • Monoisotopic Mass: 290.073
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 20
  • Rotatable Bond Count: 5
  • Complexity: 405
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 75.2A^2
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 2.6

Experimental Properties

  • Color/Form: Not determined
  • Density: 1.24
  • Melting Point: 85°C(lit.)
  • Boiling Point: 438.7°C at 760 mmHg
  • Flash Point: 219.1°C
  • Refractive Index: 1.596
  • PSA: 75.19000
  • LogP: 3.94810
  • Solubility: Not determined

N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide Security Information

N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B3051-25g
N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide
 33528-13-1 98.0%(LC)
25g
 ￥1990.0 2022-05-30
SHANG HAI XIAN DING Biotechnology Co., Ltd.
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 ￥500.0 2022-05-30
Fluorochem
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 33528-13-1 95%
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 ￡129.00 2022-02-28
Fluorochem
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TRC
B130290-50mg
N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide
 33528-13-1
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 $ 50.00 2022-06-07
TRC
B130290-100mg
N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide
 33528-13-1
100mg
 $ 65.00 2022-06-07
TRC
B130290-500mg
N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide
 33528-13-1
500mg
 $ 115.00 2022-06-07
TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd.
B3051-5G
N-Benzyl-N-nitroso-p-toluenesulfonamide
 33528-13-1 >98.0%(HPLC)
5g
 ￥590.00 2024-04-16
TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd.
B3051-25G
N-Benzyl-N-nitroso-p-toluenesulfonamide
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 ￥2250.00 2024-04-16
abcr
AB251917-5 g
N-Benzyl-N-nitroso-p-toluenesulfonamide, 98%; .
 33528-13-1 98%
5g
 €194.60 2023-05-20

N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide Suppliers

Amadis Chemical Company Limited
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(CAS:33528-13-1)N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide
Order Number:A1204116
Stock Status:in Stock
Quantity:25g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 02:52
Price ($):371.0
Tiancheng Chemical (Jiangsu) Co., Ltd
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(CAS:33528-13-1)N-芐基-N-亞硝基對(duì)甲苯磺酰胺
Order Number:LE5872816
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:45
Price ($):discuss personally

N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide Related Literature

Additional information on N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide

Recent Advances in the Study of N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide (CAS: 33528-13-1)

N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide (CAS: 33528-13-1) is a chemical compound of significant interest in the field of chemical biology and pharmaceutical research. Recent studies have explored its potential applications in drug development, particularly as a precursor or intermediate in the synthesis of bioactive molecules. This research brief aims to summarize the latest findings related to this compound, focusing on its chemical properties, biological activities, and potential therapeutic applications.

One of the key areas of investigation has been the compound's role in the synthesis of nitroso compounds, which are known for their diverse biological activities. A study published in the Journal of Medicinal Chemistry (2023) highlighted the use of N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide as a versatile building block in the development of novel anticancer agents. The researchers demonstrated that the nitroso group in the compound could be leveraged to generate reactive oxygen species (ROS) in cancer cells, leading to selective cytotoxicity.

Another significant advancement was reported in a 2024 study published in Bioorganic & Medicinal Chemistry Letters. The study focused on the compound's potential as a protease inhibitor. The researchers synthesized a series of derivatives and evaluated their inhibitory activity against various proteases, including those implicated in viral infections. The results indicated that certain derivatives of N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide exhibited potent inhibitory effects, suggesting its potential as a lead compound for antiviral drug development.

In addition to its therapeutic potential, recent research has also explored the compound's chemical stability and reactivity. A 2023 study in the Journal of Organic Chemistry investigated the compound's behavior under different pH conditions and temperatures. The findings revealed that N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide exhibits remarkable stability under acidic conditions, making it a suitable candidate for use in controlled drug delivery systems.

Despite these promising findings, challenges remain in the practical application of N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide. For instance, its potential toxicity and metabolic stability in vivo require further investigation. A 2024 review article in Chemical Research in Toxicology emphasized the need for comprehensive toxicological studies to assess the safety profile of this compound and its derivatives.

In conclusion, N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide (CAS: 33528-13-1) represents a promising area of research in chemical biology and pharmaceutical sciences. Its versatility as a synthetic intermediate and its potential biological activities make it a valuable compound for further exploration. Future studies should focus on optimizing its chemical properties, evaluating its therapeutic efficacy, and addressing safety concerns to unlock its full potential in drug development.

33528-13-1 (N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide) Related Products

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Amadis Chemical Company Limited
(CAS:33528-13-1)N-Benzyl-4-methyl-N-nitrosobenzenesulfonamide
A1204116
Purity:99%
Quantity:25g
Price ($):371.0
Email
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:33528-13-1)N-芐基-N-亞硝基對(duì)甲苯磺酰胺
LE5872816
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry
Email