• 1. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?
  Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198
• 2. Emulsion soft templating of carbide-derived carbon nanospheres with controllable porosity for capacitive electrochemical energy storage?
  M. Zeiger,N. J?ckel,P. Strubel,L. Borchardt,R. Reinhold,W. Nickel,J. Eckert,V. Presser,S. Kaskel J. Mater. Chem. A, 2015,3, 17983-17990
• 3. Fast-pulsing NMR techniques for the detection of weak interactions: successful natural abundance probe of hydrogen bonds in peptides?
  Amandine Altmayer-Henzien,Valérie Declerck,David J. Aitken,Ewen Lescop,Denis Merlet,Jonathan Farjon Org. Biomol. Chem., 2013,11, 7611-7615
• 4. Evolution of dealloying induced strain in nanoporous gold crystals?
  Ross Harder,David C. Dunand,Ian McNulty Nanoscale, 2017,9, 5686-5693
• 5. Estimates of hydride ion stability in condensed systems: energy of formation and solvation in aqueous and polar-organic solvents
  Craig A. Kelly,David R. Rosseinsky Phys. Chem. Chem. Phys., 2001,3, 2086-2090

• Solvents and Organic Chemicals Organic Compounds Benzenoids Phenol ethers Anisoles

1-Bromo-2-Methoxy-4,5-Dimethylbenzene: A Comprehensive Overview

1-Bromo-2-Methoxy-4,5-Dimethylbenzene (CAS No. 33500-88-8) is a versatile aromatic compound with a unique substitution pattern on the benzene ring. This compound has garnered significant attention in recent years due to its potential applications in various fields, including organic synthesis, material science, and pharmacology. The molecule consists of a bromine atom at position 1, a methoxy group at position 2, and two methyl groups at positions 4 and 5 on the benzene ring. This specific arrangement of substituents imparts distinct chemical properties that make it valuable for both academic and industrial purposes.

The synthesis of 1-bromo-2-methoxy-4,5-dimethylbenzene has been extensively studied. Recent advancements in catalytic methods have enabled more efficient and environmentally friendly routes for its production. For instance, researchers have explored the use of palladium-catalyzed cross-coupling reactions to construct the desired substitution pattern. These methods not only improve yield but also reduce the environmental footprint compared to traditional bromination techniques.

One of the most notable applications of 1-bromo-2-methoxy-4,5-dimethylbenzene is in the field of organic synthesis as an intermediate for constructing complex aromatic molecules. Its bromine atom serves as an excellent leaving group, facilitating nucleophilic aromatic substitution reactions. This property has been exploited in the synthesis of various biologically active compounds, including pharmaceutical agents and agrochemicals.

Recent studies have also highlighted the potential of 1-bromo-2-methoxy-4,5-dimethylbenzene in materials science. For example, derivatives of this compound have been investigated as precursors for advanced materials such as conductive polymers and organic semiconductors. The methyl groups at positions 4 and 5 contribute to the molecule's stability and electronic properties, making it a promising candidate for these applications.

In terms of pharmacology, 1-bromo-2-methoxy-4,5-dimethylbenzene has shown potential as a lead compound for drug discovery. Its substitution pattern allows for fine-tuning of pharmacokinetic properties such as solubility and bioavailability. Researchers have explored its role in inhibiting key enzymes involved in metabolic pathways, offering new avenues for therapeutic development.

The toxicological profile of 1-bromo-2-methoxy-4,5-dimethylbenzene has also been a subject of recent research. Studies indicate that while the compound exhibits moderate toxicity in acute exposure scenarios, its chronic effects require further investigation. Regulatory bodies are closely monitoring its use to ensure compliance with safety standards.

Looking ahead, the demand for 1-bromo-2-methoxy-4,5-dimethylbenzene is expected to grow due to its versatility and expanding range of applications. Ongoing research is focused on optimizing its synthesis pathways and exploring novel uses in emerging fields such as green chemistry and sustainable materials development.

• 51699-89-9(2,6-Dibromo-4-methylanisole)
• 725227-63-4(Benzene,1-bromo-5-ethyl-2-methoxy-4-methyl-)
• 103260-55-5(2-Bromo-1-ethoxy-4-methylbenzene)
• 95740-49-1(1-bromo-2-methoxy-4-methylbenzene)
• 22002-45-5(3-Bromo-4-methoxy toluene)
• 22802-39-7(2-Bromo-4,5-dimethylphenol)
• 17100-64-0((4-Bromo-3-methoxyphenyl)methanol)
• 162269-87-6(Benzene, 1-bromo-2-(methoxymethoxy)-4,5-dimethyl-)
• 39763-70-7(Benzene, 1,1'-oxybis[2-bromo-4,5-dimethyl-)
• 38493-59-3(3-Bromo-4-methoxybenzyl Alcohol)