Cas no 33406-96-1 (2-Chloro-5-fluorotoluene)

2-Chloro-5-fluorotoluene (CAS 2613-34-5) is a halogenated aromatic compound featuring both chloro and fluoro substituents on a toluene backbone. This structure imparts unique reactivity, making it a valuable intermediate in organic synthesis, particularly in pharmaceuticals and agrochemicals. The electron-withdrawing effects of the halogens enhance its utility in cross-coupling reactions, nucleophilic substitutions, and other functionalizations. Its high purity and stability under standard conditions ensure consistent performance in laboratory and industrial applications. The compound's well-defined physical and chemical properties, including boiling point and solubility, facilitate precise handling and integration into synthetic pathways. It is commonly used in the development of active pharmaceutical ingredients (APIs) and specialty chemicals.
2-Chloro-5-fluorotoluene structure
2-Chloro-5-fluorotoluene structure
Product Name:2-Chloro-5-fluorotoluene
CAS No:33406-96-1
MF:C7H6ClF
MW:144.573944568634
MDL:MFCD00040853
CID:54073
PubChem ID:118475
Update Time:2025-05-24

2-Chloro-5-fluorotoluene Chemical and Physical Properties

Names and Identifiers

    • 1-Chloro-4-fluoro-2-methylbenzene
    • 2-Chloro-5-fluorotoluene
    • 2-Chlor-5-fluor-toluol
    • 3-FLUORO-6-CHLOROTOLUENE
    • 5-fluoro-2-chlorotoluene
    • 6-Chlor-3-fluortoluol
    • Benzene,1-chloro-4-fluoro-2-methyl
    • AKOS005255218
    • NS00054625
    • F0001-0985
    • AC-13800
    • FT-0611822
    • J-508836
    • 33406-96-1
    • EINECS 251-508-6
    • EN300-153406
    • F11232
    • SCHEMBL600882
    • Benzene, 1-chloro-4-fluoro-2-methyl-
    • DTXSID10187053
    • CS-W013314
    • MFCD00040853
    • PS-11942
    • AM61461
    • 2-Chloro-5-fluorotoluene,98%
    • DB-023906
    • MDL: MFCD00040853
    • Inchi: 1S/C7H6ClF/c1-5-4-6(9)2-3-7(5)8/h2-4H,1H3
    • InChI Key: NIOGDCDTKPQEAT-UHFFFAOYSA-N
    • SMILES: ClC1C=CC(=CC=1C)F
    • BRN: 2041494

Computed Properties

  • Exact Mass: 144.01400
  • Monoisotopic Mass: 144.014
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 9
  • Rotatable Bond Count: 0
  • Complexity: 94.9
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: nothing
  • Topological Polar Surface Area: 0A^2

Experimental Properties

  • Color/Form: No data available
  • Density: 1.2000
  • Melting Point: No data available
  • Boiling Point: 156-157℃
  • Flash Point: 51℃
  • Refractive Index: 1.5000
  • PSA: 0.00000
  • LogP: 2.78750
  • Solubility: Not determined

2-Chloro-5-fluorotoluene Security Information

2-Chloro-5-fluorotoluene Customs Data

  • HS CODE:2903999090
  • Customs Data:

    China Customs Code:

    2903999090

    Overview:

    2903999090 Other aromatic halogenated derivatives. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:5.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

2-Chloro-5-fluorotoluene Pricemore >>

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2-Chloro-5-fluorotoluene Suppliers

Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:33406-96-1)2-Chloro-5-fluorotoluene
Order Number:1647769
Stock Status:in Stock
Quantity:Company Customization
Purity:98%
Pricing Information Last Updated:Monday, 14 April 2025 21:49
Price ($):discuss personally
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:33406-96-1)2-氯-5-氟甲苯
Order Number:LE1647769
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:31
Price ($):discuss personally

Additional information on 2-Chloro-5-fluorotoluene

Comprehensive Overview of 2-Chloro-5-fluorotoluene (CAS No. 33406-96-1): Properties, Applications, and Industry Insights

2-Chloro-5-fluorotoluene (CAS No. 33406-96-1) is a halogenated aromatic compound widely recognized for its versatility in organic synthesis and industrial applications. This chloro-fluorotoluene derivative combines the reactivity of chlorine and fluorine substituents on a toluene backbone, making it a valuable intermediate in pharmaceuticals, agrochemicals, and specialty chemicals. Its molecular formula, C7H6ClF, and precise structural features contribute to its unique physicochemical properties, including a boiling point of 160-162°C and a molecular weight of 144.57 g/mol.

In recent years, the demand for fluorinated toluene derivatives like 2-Chloro-5-fluorotoluene has surged due to their role in developing high-performance materials and active pharmaceutical ingredients (APIs). Researchers frequently search for "synthesis methods for 2-Chloro-5-fluorotoluene" or "CAS 33406-96-1 suppliers," reflecting its commercial and scientific relevance. The compound’s stability under mild conditions and compatibility with cross-coupling reactions (e.g., Suzuki or Heck reactions) further enhance its utility in modern synthetic chemistry.

From an environmental and regulatory perspective, 2-Chloro-5-fluorotoluene is subject to standard handling protocols for halogenated compounds. Industries emphasize "safe storage of chloro-fluorotoluene" and "33406-96-1 MSDS guidelines" to ensure compliance with global safety standards. Innovations in green chemistry have also spurred interest in optimizing its production processes to minimize waste and energy consumption, aligning with the sustainable chemical manufacturing trends.

The compound’s applications extend to the development of liquid crystal displays (LCDs) and electronic materials, where its fluorine moiety improves thermal stability and optical properties. Additionally, its use in crop protection agents highlights its agrochemical significance, addressing queries like "2-Chloro-5-fluorotoluene in pesticide formulation." Analytical techniques such as GC-MS and HPLC are commonly employed to verify its purity, a critical factor for end-users.

Market analyses indicate steady growth for halogenated intermediates, driven by advancements in pharmaceutical R&D and material science. As a result, CAS 33406-96-1 remains a focal point for suppliers and researchers alike. Future developments may explore its potential in bioconjugation or catalysis, further expanding its industrial footprint. For those sourcing this compound, verifying "technical specifications of 2-Chloro-5-fluorotoluene" and "33406-96-1 pricing trends" is recommended to ensure optimal procurement strategies.

Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:33406-96-1)2-Chloro-5-fluorotoluene
1647769
Purity:98%
Quantity:Company Customization
Price ($):Inquiry
Email
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:33406-96-1)2-氯-5-氟甲苯
LE1647769
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry
Email