Cas no 33342-05-1 (Gliquidone)
Gliquidone is a second-generation sulfonylurea oral hypoglycemic agent used primarily in the management of type 2 diabetes mellitus. It functions by stimulating insulin secretion from pancreatic β-cells, thereby reducing blood glucose levels. Gliquidone is distinguished by its short half-life and rapid elimination, minimizing the risk of prolonged hypoglycemia. It is metabolized primarily in the liver, with ~95% excreted via bile, making it suitable for patients with mild to moderate renal impairment. The drug exhibits high selectivity for sulfonylurea receptors, enhancing its efficacy and safety profile. Its flexible dosing and low hypoglycemic risk make it a practical option for glycemic control in eligible patients.
Gliquidone structure
Product Name:Gliquidone
CAS No:33342-05-1
MF:C27H33N3O6S
MW:527.632426023483
MDL:MFCD00631870
CID:54060
PubChem ID:87560715
Update Time:2025-05-27
Gliquidone Chemical and Physical Properties
Names and Identifiers
-
- Gliquidone
- 1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylurea
- Beglynor
- Beglynora
- glikvidon
- Gliquidona
- Gliquidonum
- Glurenorm
- glycvidon
- 3-Cyclohexyl-1-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-isoquinolin-2-yl)ethyl]phenyl]sulfonyl-urea
- AR-DF 26
- Glurenorm (TN)
- BPBio1_001191
- HMS3652O05
- 1-cyclohexyl-3-({4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]benzene}sulfonyl)urea
- EN300-708770
- S3151
- A821736
- ARDF-26
- 4,4-dimethyl-1,3-dioxo-3,4-dihydroisoquinolin
- N-(cyclohexylcarbamoyl)-4-(2-(7-methoxy-
- GLIQUIDONE [INN]
- Benzenesulfonamide, N-[(cyclohexylamino)carbonyl]-4-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolinyl)ethyl]-; AR-DF 26; ARDF 26SE; Beglynor; Gliquidone; Glurenorm
- BDBM50248247
- Benzenesulfonamide, N-((cyclohexylamino)carbonyl)-4-(2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolinyl)ethyl)-
- CCG-220991
- ARDF 26
- NCGC00179315-01
- AB00513989_07
- Gliquidone [INN:BAN]
- D02430
- Z56785257
- UNII-C7C2QDD75P
- AB00513989
- Prestwick0_000991
- Tox21_110629_1
- 3-cyclohexyl-1-({4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]benzene}sulfonyl)urea
- -2(1H)-yl)ethyl)benzenesulfonamide
- Prestwick2_000991
- NCGC00016819-03
- Gliquidone, 98%
- T72318
- Prestwick3_000991
- CHEMBL383634
- SR-01000833866
- BSPBio_001081
- SR-01000833866-2
- 1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-2-isoquinolinyl)ethyl]phenyl]sulfonylurea
- AC-23356
- HMS3715G03
- HMS2098G03
- CHEBI:93416
- MLS000881123
- SW197285-3
- CAS-33342-05-1
- DTXSID4023096
- FT-0630570
- HY-B1114
- G0332
- BCP11927
- SMR000685793
- 1-CYCLOHEXYL-3-(((P-(2-(3,4-DIHYDRO-7-METHOXY-4,4-DIMETHYL-1,3-DIOXO-2(1H)-ISOQUINOLYL)ETHYL)PHENYL)SULFONYL)UREA
- NCGC00016819-06
- DTXCID403096
- 1-Cyclohexyl-3-(p-beta-(4,4-dimethyl-2-methoxy-1,3-(2H,4H)-isoquinolinedione-2-yl)phenethyl)sulfonylurea
- NCGC00016819-01
- Q5569924
- EINECS 251-463-2
- 1-Cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-2-isoquinolyl)ethyl]phenyl]sulfonyl-urea;Gliquidone
- NCGC00016819-02
- MLS002154087
- BRD-K80396088-001-03-9
- MLS000881174
- Gliquidone (INN)
- N-(Cyclohexylcarbamoyl)-4-(2-(7-methoxy-4,4-dimethyl-1,3-dioxo-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)benzenesulfonamide
- Prestwick1_000991
- Gliquidonum [INN-Latin]
- J-019153
- AKOS001037880
- 1-Cyclohexyl-3-((p-(2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolyl)ethyl)phenyl)sulfonyl)urea
- Tox21_110629
- Gliquidona [INN-Spanish]
- BRN 1559726
- NS00007815
- DB01251
- GLIQUIDONE [MART.]
- N-cyclohexylcarbamoyl-4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-1,2,3,4- tetrahydroisoquinolin-2-yl)ethyl]benzenesulfonamide
- 1-cyclohexyl-3-{4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]benzenesulfonyl}urea
- GLIQUIDONE [MI]
- SCHEMBL37769
- CS-4646
- HMS1571G03
- ARDF 26 SE
- MFCD00631870
- Gliquidone,(S)
- HMS2964J06
- C7C2QDD75P
- Gliquidon
- N-[(cyclohexylamino)carbonyl]-4-{2-[4,4-dimethyl-7-(methyloxy)-1,3-dioxo-3,4-dihydroisoquinolin-2(1H)-yl]ethyl}benzenesulfonamide
- GLIQUIDONE [WHO-DD]
- NCGC00016819-05
- SPBio_002972
- KS-5239
- 33342-05-1
- Oprea1_069443
- 62783-47-5
- BRD-K80396088-001-12-0
- Glurenor
- N-cyclohexylcarbamoyl-4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]benzenesulfonamide
- Gliquidona (INN-Spanish)
- Gliquidone (AR-DF26)
- Gliquidonum (INN-Latin)
- LLJFMFZYVVLQKT-UHFFFAOYSA-N
- 3-cyclohexyl-1-((4-(2-(7-methoxy-4,4-dimethyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl)benzene)sulfonyl)urea
- SCHEMBL26496471
- GLIQUIDONE (MART.)
- N-[(cyclohexylamino)carbonyl]-4-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxoisoquinolin-2(1h)-yl)ethyl]benzenesulfonamide
- A10BB08
- N-cyclohexylcarbamoyl-4-(2-(7-methoxy-4,4-dimethyl-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl)benzenesulfonamide
- N-(Cyclohexylcarbamoyl)-4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-3,4-dihydroisoquinolin-2(1H)-yl)ethyl]benzenesulfonamide
- DB-366405
- 1ST10097
-
- MDL： MFCD00631870
- Inchi： 1S/C27H33N3O6S/c1-27(2)23-14-11-20(36-3)17-22(23)24(31)30(25(27)32)16-15-18-9-12-21(13-10-18)37(34,35)29-26(33)28-19-7-5-4-6-8-19/h9-14,17,19H,4-8,15-16H2,1-3H3,(H2,28,29,33)
- InChI Key： LLJFMFZYVVLQKT-UHFFFAOYSA-N
- SMILES： S(C1C=CC(=CC=1)CCN1C(C2C=C(C=CC=2C(C)(C)C1=O)OC)=O)(NC(NC1CCCCC1)=O)(=O)=O
- BRN： 1559726
Computed Properties
- Exact Mass: 527.20900
- Monoisotopic Mass: 527.209
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 9
- Heavy Atom Count: 37
- Rotatable Bond Count: 9
- Complexity: 948
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 130A^2
- XLogP3: 4.6
Experimental Properties
- Color/Form: Powder
- Density: 1.34
- Melting Point: 177.0 to 188.3 deg-C
- Boiling Point: °Cat760mmHg
- Flash Point: °C
- Refractive Index: 1.624
- Solubility: biological extracorporealIn Vitro:H2O< 0.1 mg/mL(insoluble)
- PSA: 130.26000
- LogP: 5.31900
- Merck: 4443
Gliquidone Security Information
- Signal Word：Warning
- Hazard Statement： H315; H319; H335
- Warning Statement： P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501
- Safety Instruction： 24/25
- RTECS：DB1584250
- Storage Condition：Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month
Gliquidone Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| YUN NAN XI LI SHENG WU JI SHU GU FEN Co., Ltd. | BBP80154-5mg |
Gliquidone |
33342-05-1 | 98.0% | 5mg |
￥100 | 2021-05-07 | |
| MedChemExpress | HY-B1114-10mM*1mLinDMSO |
Gliquidone |
33342-05-1 | 99.52% | 10mM*1mLinDMSO |
￥550 | 2023-07-26 | |
| MedChemExpress | HY-B1114-50mg |
Gliquidone |
33342-05-1 | 99.52% | 50mg |
￥500 | 2024-04-18 | |
| MedChemExpress | HY-B1114-100mg |
Gliquidone |
33342-05-1 | 99.52% | 100mg |
￥600 | 2024-04-18 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | G129565-5g |
Gliquidone |
33342-05-1 | ≥98% | 5g |
￥990.90 | 2023-09-02 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | G129565-1g |
Gliquidone |
33342-05-1 | ≥98% | 1g |
￥340.90 | 2023-09-02 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | LG0367-1g |
Gliquidone |
33342-05-1 | ≥98% | 1g |
￥510元 | 2023-09-15 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | LG0367-5g |
Gliquidone |
33342-05-1 | ≥98% | 5g |
￥1620元 | 2023-09-15 | |
| DC Chemicals | DCG-021-20 mg |
Gliquidone |
33342-05-1 | >98%, Standard References Grade | 20mg |
$280.0 | 2022-02-28 | |
| S e l l e c k ZHONG GUO | S3151-10mM (1mL in DMSO) |
Gliquidone |
33342-05-1 | 99.97% | 10mM (1mL in DMSO) |
￥736.94 | 2023-09-15 |
Gliquidone Suppliers
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:33342-05-1)Gliquidone
Order Number:sfd2616
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:33
Price ($):discuss personally
Email:[email protected]
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:33342-05-1)Gliquidone
Order Number:LE10395
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:03
Price ($):discuss personally
Email:[email protected]
Gliquidone Related Literature
-
Zhigui Zhou,Jialing Zhang,Wei Zhang,Yu Bai,Huwei Liu Analyst 2011 136 2613
-
Lina Jia,Yang Yu,Mengwei Wang,Hanzhi Ouyang,Junbo Gong CrystEngComm 2019 21 1617
-
Xuan Wang,Juan-Juan Zhao,Qian Zhang,Xing-Cai Wang,Yu-Ying Zhang,Jie-Jie Zhou,Yi Lv,Yong-Jie Yu,Hai-Yan Fu,Yuanbin She Anal. Methods 2021 13 1731
-
Margarida Estudante,Gra?a Soveral,José G. Morais,Leslie Z. Benet Med. Chem. Commun. 2016 7 1462
-
Mengdi Wang,Yan Liang,Keqi Chen,Maolong Wang,Xuehua Long,HongLing Liu,Yong Sun,Bin He Nanoscale 2022 14 2119
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