Cas no 330792-75-1 (N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)aniline)

N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is a boronic ester derivative widely utilized as a key intermediate in Suzuki-Miyaura cross-coupling reactions. Its stable dioxaborolane moiety enhances handling and storage compared to boronic acids, while the phenylamine substituent facilitates incorporation into complex organic frameworks. This compound is particularly valuable in pharmaceutical and materials science research, enabling the synthesis of biaryl structures with high efficiency. Its crystalline solid form ensures consistent purity, and its compatibility with diverse reaction conditions makes it a versatile reagent. The product is typically characterized by NMR and HPLC to verify structural integrity and suitability for demanding synthetic applications.
N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)aniline structure
330792-75-1 structure
Product Name:N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)aniline
CAS No:330792-75-1
MF:C18H22BNO2
MW:295.1837849617
CID:2127508
PubChem ID:22347219
Update Time:2025-05-20

N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)aniline Chemical and Physical Properties

Names and Identifiers

    • N-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine
    • N-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
    • XMHGCOWOUZMADX-UHFFFAOYSA-N
    • MB18396
    • SCHEMBL1129188
    • DB-343911
    • BS-48423
    • EN300-12603598
    • 330792-75-1
    • CS-0356528
    • N-phenyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
    • 1-(Phenylamino)-benzene-4-boronic Acid Pinacol Ester
    • N-phenyl-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]amine
    • starbld0031634
    • E80459
    • N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)aniline
    • Inchi： 1S/C18H22BNO2/c1-17(2)18(3,4)22-19(21-17)14-10-12-16(13-11-14)20-15-8-6-5-7-9-15/h5-13,20H,1-4H3
    • InChI Key： XMHGCOWOUZMADX-UHFFFAOYSA-N
    • SMILES： O1B(C2C=CC(=CC=2)NC2C=CC=CC=2)OC(C)(C)C1(C)C

Computed Properties

  • Exact Mass: 295.1743591g/mol
  • Monoisotopic Mass: 295.1743591g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 22
  • Rotatable Bond Count: 3
  • Complexity: 355
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 30.5

N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)aniline Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
ChemScence
CS-0356528-5g
N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
 330792-75-1
5g
 $69.0 2022-04-27
ChemScence
CS-0356528-25g
N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
 330792-75-1
25g
 $211.0 2022-04-27
Aaron
AR00CN1D-10g
N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
 330792-75-1 95%
10g
 $104.00 2025-02-13
Aaron
AR00CN1D-100mg
N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
 330792-75-1 95%
100mg
 $6.00 2025-02-13
Aaron
AR00CN1D-250mg
N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
 330792-75-1 95%
250mg
 $9.00 2025-02-13
Aaron
AR00CN1D-1g
N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
 330792-75-1 95%
1g
 $18.00 2025-02-13
Aaron
AR00CN1D-5g
N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
 330792-75-1 95%
5g
 $64.00 2025-02-13
Aaron
AR00CN1D-25g
N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
 330792-75-1 95%
25g
 $200.00 2025-02-13
1PlusChem
1P00CMT1-1g
N-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
 330792-75-1 95%
1g
 $20.00 2024-05-05
1PlusChem
1P00CMT1-5g
N-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
 330792-75-1 95%
5g
 $63.00 2024-05-05

N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)aniline Related Literature

Additional information on N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)aniline

Comprehensive Overview of N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)aniline (CAS No. 330792-75-1)

N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)aniline, with the CAS number 330792-75-1, is a highly specialized boronic ester derivative that has garnered significant attention in the fields of organic synthesis, pharmaceutical research, and material science. This compound is particularly valued for its role as a key intermediate in Suzuki-Miyaura cross-coupling reactions, a widely used method for forming carbon-carbon bonds. Its unique boron-containing structure makes it a versatile building block for the development of advanced drug candidates and functional materials.

The growing interest in N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)aniline is driven by its applications in targeted drug delivery systems and bioconjugation. Researchers are increasingly exploring its potential in designing proteolysis-targeting chimeras (PROTACs), a cutting-edge therapeutic approach that has become a hot topic in cancer research. Additionally, its stability and reactivity under mild conditions make it a preferred choice for high-throughput screening and combinatorial chemistry.

From an industrial perspective, CAS 330792-75-1 is often utilized in the synthesis of OLED materials and organic semiconductors, aligning with the global push toward sustainable electronics. Its compatibility with green chemistry principles has also made it a subject of interest for companies aiming to reduce environmental impact. Recent studies highlight its role in developing energy-efficient lighting solutions, a topic frequently searched in scientific databases and patent filings.

One of the most frequently asked questions about N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)aniline revolves around its synthetic scalability and purity standards. Advanced purification techniques, such as column chromatography and recrystallization, are often employed to achieve the high purity required for pharmaceutical-grade applications. Furthermore, its storage conditions and shelf life are critical considerations for laboratories and manufacturers, as improper handling can affect its reactivity and yield.

In the context of academic research, this compound is frequently cited in studies exploring boron-based therapeutics and catalysis. Its molecular structure allows for precise modifications, enabling scientists to tailor its properties for specific applications. For instance, its incorporation into fluorescent probes has opened new avenues in bioimaging and diagnostics, addressing the rising demand for non-invasive medical technologies.

The market demand for CAS 330792-75-1 is expected to grow steadily, driven by its expanding applications in personalized medicine and smart materials. As AI-driven drug discovery gains traction, the need for reliable chemical intermediates like this compound is projected to increase. Companies specializing in custom synthesis and contract research are actively investing in its production to meet the needs of biotech startups and academic institutions.

In summary, N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)aniline (330792-75-1) represents a critical component in modern chemical innovation. Its multifaceted applications, from drug development to advanced materials, underscore its importance in both scientific research and industrial processes. As the scientific community continues to uncover its potential, this compound is poised to play a pivotal role in shaping the future of molecular engineering and sustainable technology.

330792-75-1 (N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)aniline) Related Products

Recommended suppliers
Suzhou Genelee Bio-Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Suzhou Genelee Bio-Technology Co., Ltd.
ASIACHEM I&E (JIANGSU) CO., LTD
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
ASIACHEM I&E (JIANGSU) CO., LTD
Shandong Feiyang Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shandong Feiyang Chemical Co., Ltd
Shenzhen Yaoyuan R&D Center Co.,Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shenzhen Yaoyuan R&D Center Co.,Ltd
Shanghai Joy Biotech Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shanghai Joy Biotech Ltd