Cas no 328071-25-6 (1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid)

1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid is a pyrazole derivative with a hydroxyl and carboxylic acid functional group, offering versatility in synthetic chemistry applications. Its structure enables use as an intermediate in pharmaceuticals, agrochemicals, and coordination chemistry due to its chelating potential. The presence of both hydrophilic (hydroxyethyl) and reactive (carboxylic acid) groups enhances solubility and reactivity, facilitating modifications for targeted molecular design. This compound is particularly valuable in heterocyclic synthesis, where its stability and functional group compatibility support the development of complex structures. High purity grades ensure consistent performance in research and industrial processes.

1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid structure

328071-25-6 structure

Product Name:1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid

CAS No:328071-25-6

MF:C₇H₁₀N₂O₃

MW:170.165901660919

MDL:MFCD00518743

CID:878303

Update Time:2025-06-11

1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid Chemical and Physical Properties

Names and Identifiers

- 1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid
- Oprea1_327643
- Pyrazole-5-carboxylic acid, 1-(2-hydroxyethyl)-3-methyl-
- FOKYHSZFJQNCNU-UHFFFAOYSA-N
- 1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid #
- MDL： MFCD00518743
- Inchi： 1S/C7H10N2O3/c1-5-4-6(7(11)12)9(8-5)2-3-10/h4,10H,2-3H2,1H3,(H,11,12)
- InChI Key： FOKYHSZFJQNCNU-UHFFFAOYSA-N
- SMILES： OCCN1C(C(=O)O)=CC(C)=N1

Computed Properties

Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 4
Heavy Atom Count: 12
Rotatable Bond Count: 3
Complexity: 174
Topological Polar Surface Area: 75.4

1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
TRC	B444283-10mg	1-(2-hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid	328071-25-6		10mg	$ 50.00	2022-06-07
TRC	B444283-50mg	1-(2-hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid	328071-25-6		50mg	$ 210.00	2022-06-07
TRC	B444283-100mg	1-(2-hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid	328071-25-6		100mg	$ 295.00	2022-06-07
Chemenu	CM517205-1g	1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid	328071-25-6	98%	1g	$559	2022-06-11
SHANG HAI HAO HONG Biomedical Technology Co., Ltd.	1521746-1g	1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid	328071-25-6	98%	1g	￥5825.00	2024-08-02
A2B Chem LLC	AG03387-50mg	1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid	328071-25-6	95%	50mg	$277.00	2024-04-20
A2B Chem LLC	AG03387-100mg	1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid	328071-25-6	95%	100mg	$395.00	2024-04-20
A2B Chem LLC	AG03387-250mg	1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid	328071-25-6	95%	250mg	$548.00	2024-04-20
A2B Chem LLC	AG03387-500mg	1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid	328071-25-6	95%	500mg	$844.00	2024-04-20
A2B Chem LLC	AG03387-1g	1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid	328071-25-6	95%	1g	$1073.00	2024-04-20

1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid Suppliers

Amadis Chemical Company Limited

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Audited Supplier

(CAS:328071-25-6)1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid

Order Number:A1085403

Stock Status:in Stock

Quantity:1g

Purity:99%

Pricing Information Last Updated:Thursday, 29 August 2024 19:23

Price ($):557.0

Email:[email protected]

Product Official Link

1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid Related Literature

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Analyst, 1880,5, 146-147
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3. Exciplex emission from the mixed dimer of naphthalene and 2-cyanonaphthalene in a supersonic jet

Aloke Das,K. K. Mahato,Chayan K. Nandi,Tapas Chakraborty,Shridhar R. Gadre,Nikhil A. Gokhale Phys. Chem. Chem. Phys., 2002,4, 2162-2168
4. Enabling chloride salts for thermal energy storage: implications of salt purity?

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Additional information on 1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid

Recent Advances in the Study of 1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid (CAS: 328071-25-6)

1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid (CAS: 328071-25-6) is a pyrazole derivative that has garnered significant attention in the field of chemical biology and medicinal chemistry due to its versatile applications in drug discovery and development. Recent studies have explored its potential as a key intermediate in the synthesis of novel bioactive compounds, particularly in the areas of anti-inflammatory, antimicrobial, and anticancer therapeutics. This research briefing aims to provide an overview of the latest findings related to this compound, highlighting its chemical properties, biological activities, and potential therapeutic applications.

A recent study published in the Journal of Medicinal Chemistry investigated the role of 1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid as a precursor in the synthesis of small-molecule inhibitors targeting protein kinases. The study demonstrated that derivatives of this compound exhibited potent inhibitory activity against specific kinase isoforms involved in cancer cell proliferation. The researchers utilized a combination of molecular docking and in vitro assays to validate the binding affinity and selectivity of these derivatives, paving the way for further optimization and preclinical evaluation.

In another groundbreaking study, researchers explored the antimicrobial properties of 1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid derivatives against multidrug-resistant bacterial strains. The results, published in Bioorganic & Medicinal Chemistry Letters, revealed that certain modifications to the pyrazole core significantly enhanced the compound's efficacy against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA). These findings underscore the potential of this compound as a scaffold for developing new antibiotics to address the growing threat of antimicrobial resistance.

Additionally, a collaborative research effort between academic and industrial laboratories has focused on the metabolic stability and pharmacokinetic profile of 1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid. The study, detailed in Drug Metabolism and Disposition, employed advanced LC-MS/MS techniques to assess the compound's bioavailability and clearance rates in preclinical models. The data suggested that structural modifications could improve its metabolic stability, making it a more viable candidate for further drug development.

In conclusion, the latest research on 1-(2-Hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid (CAS: 328071-25-6) highlights its multifaceted potential in medicinal chemistry. From kinase inhibition to antimicrobial activity, this compound serves as a promising scaffold for the design of novel therapeutics. Future studies should focus on optimizing its pharmacological properties and advancing it through the drug development pipeline to fully realize its therapeutic potential.

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