• 1. Aggregation-induced emission based on a fluorinated macrocycle: visualizing spontaneous and ultrafast solid-state molecular motions at room temperature via F?F interactions?
  Mei Zhang,Jingjing Guo,Tingting Liu,Zhanyu He,Majeed Irfan,Zujin Zhao,Zhuo Zeng J. Mater. Chem. C, 2020,8, 14919-14924
• 2. An automatic determination of thoria in thoria-urania mixtures
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• 3. Aggregation behaviour of biocompatible choline carboxylate ionic liquids and their interactions with biomolecules through experimental and theoretical investigations?
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• Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds Amines Alkanolamines

Comprehensive Guide to 1,4-Diaminobutane-2,3-diol (CAS No. 32798-38-2): Properties, Applications, and Innovations

1,4-Diaminobutane-2,3-diol (CAS No. 32798-38-2) is a versatile organic compound with a unique molecular structure, combining both amine and hydroxyl functional groups. This diol-amine hybrid has garnered significant attention in pharmaceutical, biochemical, and material science research due to its potential as a chiral building block and multifunctional linker. Its systematic name, 2,3-dihydroxy-1,4-butanediamine, reflects its symmetrical diol and diamine configuration, which enables diverse reactivity patterns.

In recent years, the demand for specialty diamines and polyol derivatives like 1,4-diaminobutane-2,3-diol has surged, driven by trends in green chemistry and sustainable synthesis. Researchers frequently search for "biodegradable amine compounds" or "non-toxic diol applications," aligning with this compound's eco-friendly potential. Its ability to form hydrogen-bonded networks makes it valuable for designing self-assembling materials, a hot topic in nanotechnology forums.

The stereochemistry of 1,4-diaminobutane-2,3-diol (CAS No. 32798-38-2) is particularly intriguing. As a C2-symmetric molecule, it exists in three stereoisomeric forms: (2R,3R)-, (2S,3S)-, and the meso form. This property fuels its use in asymmetric catalysis and enantioselective synthesis, addressing the pharmaceutical industry's need for "chiral auxiliaries" and "stereocontrolled reactions." Computational studies suggest its conformational flexibility enhances molecular recognition in host-guest systems.

Industrial applications of 1,4-diaminobutane-2,3-diol span epoxy resin modifiers, chelating agents, and corrosion inhibitors. Its dual functionality allows crosslinking in water-soluble polymers, a feature explored in "smart hydrogel design" research. The compound's metal-coordination capacity also makes it relevant to "catalytic nanoparticle stabilization," a trending topic in materials science publications.

From a synthetic perspective, 1,4-diaminobutane-2,3-diol (CAS No. 32798-38-2) can be produced via bio-catalytic routes using engineered microorganisms—a response to the "enzymatic diamine production" search trend. Analytical characterization typically involves HPLC-MS and NMR spectroscopy, with its polar nature requiring specialized chromatographic methods. Recent patents highlight its derivatization into N-heterocyclic compounds for bioactive molecule development.

Ongoing research explores 1,4-diaminobutane-2,3-diol's role in carbon capture technologies, leveraging its CO2 absorption capacity—a timely application given climate change concerns. Its low cytotoxicity profile (as per OECD 423 guidelines) supports biomedical uses, including drug delivery vectors and tissue engineering scaffolds. These applications align with frequent searches for "biocompatible amine polymers" in academic databases.

The commercial availability of 1,4-diaminobutane-2,3-diol (CAS No. 32798-38-2) remains limited to specialty chemical suppliers, with purity grades ranging from 95% to 99.5%. Storage recommendations emphasize anhydrous conditions to prevent diol hydration or amine oxidation. Market analyses predict growth in its derivatives sector, particularly for photoresist additives in semiconductor manufacturing—addressing the "electronic chemicals market" search trend.

Future directions for 1,4-diaminobutane-2,3-diol research include computational property prediction using AI-assisted models and continuous flow synthesis optimization. Its potential in ionic liquid formulations for battery electrolytes responds to "energy storage materials" search volumes. As regulatory frameworks evolve, this compound's REACH compliance and life cycle assessment data will become increasingly important for industrial adoption.

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